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7TBM
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Composite structure of the dilated human nuclear pore complex (NPC) generated with a 37A in situ cryo-ET map of CD4+ T cell NPC
分子名称: DDX19, NUP107 CTD, NUP107 NTD, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-12-22
公開日2022-06-15
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (37 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
6V2D
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Crystal Structure of chromodomain of CDYL2 in complex with inhibitor UNC3866
分子名称: Chromodomain Y-like protein 2, UNC3866, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2019-11-22
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
7TBK
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Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC
分子名称: NUP107 CTD, NUP107 NTD, NUP133, ...
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-12-22
公開日2022-06-15
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (37 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7TBI
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BU of 7tbi by Molmil
Composite structure of the S. cerevisiae nuclear pore complex (NPC)
分子名称: Dyn2, Nic96 R1, Nic96 R2, ...
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-12-22
公開日2022-06-15
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (25 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7T70
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Co-crystal structure of SARS-CoV-2 Mpro C145A with substrate peptide 4/5
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Shaqra, A.M, Schiffer, C.A.
登録日2021-12-14
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance.
Nat Commun, 13, 2022
6V38
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BU of 6v38 by Molmil
Cryo-EM structure of Ca2+-bound hsSlo1 channel
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ...
著者Tao, X, MacKinnon, R.
登録日2019-11-25
公開日2019-12-25
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
7TBJ
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BU of 7tbj by Molmil
Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC
分子名称: NUP107 CTD, NUP107 NTD, NUP133, ...
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-12-22
公開日2022-06-22
最終更新日2022-06-29
実験手法ELECTRON MICROSCOPY (23 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7TBL
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BU of 7tbl by Molmil
Composite structure of the human nuclear pore complex (NPC) cytoplasmic face generated with a 12A cryo-ET map of the purified HeLa cell NPC
分子名称: DDX19, ELYS, GLE1, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-12-22
公開日2022-06-22
最終更新日2022-06-29
実験手法ELECTRON MICROSCOPY (23 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7SQ1
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BU of 7sq1 by Molmil
BG505.MD39TS Env trimer in complex with Fab from antibody C05
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ...
著者Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J.
登録日2021-11-04
公開日2022-06-22
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Nat Commun, 13, 2022
6V63
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BU of 6v63 by Molmil
SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Actin, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2019-12-04
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
7TFB
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BU of 7tfb by Molmil
P. polymyxa GS(14)-Q-GlnR peptide
分子名称: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.28 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7T67
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BU of 7t67 by Molmil
SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Byrne, P.O, McLellan, J.S.
登録日2021-12-13
公開日2022-08-24
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
7TA6
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BU of 7ta6 by Molmil
Trimer-to-Monomer Disruption of Tumor Necrosis Factor-alpha (TNF-alpha) by unnatural alpha/beta-peptide-1
分子名称: 1,2-ETHANEDIOL, AMINO GROUP, Alpha/Beta-peptide-1, ...
著者Niu, J, Bingman, C.A, Gellman, S.H.
登録日2021-12-20
公開日2022-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-alpha Signaling.
J.Am.Chem.Soc., 144, 2022
8AJQ
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BU of 8ajq by Molmil
Crystal structure of PA2722 from Pseudomonas aeruginosa PAO1
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CENP-V/GFA domain-containing protein, GLYCEROL, ...
著者Popp, M.A, Blankenfeldt, W.
登録日2022-07-28
公開日2022-10-05
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structure of PA2722 from P. aeruginosa PAO1
To Be Published
7TF9
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BU of 7tf9 by Molmil
L. monocytogenes GS(14)-Q-GlnR peptide
分子名称: C-tail peptide of Glutamine synthetase repressor, GLUTAMINE, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
6V8S
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BU of 6v8s by Molmil
Crystal structure of Ara h 8.0201
分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, Ara h 8 allergen isoform, SULFATE ION
著者Pote, S, Offermann, L.R, Hurlburt, B.K, McBride, J.K, Chruszcz, M.
登録日2019-12-12
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Ara h 8.0201
To Be Published
7TFA
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BU of 7tfa by Molmil
P. polymyxa GS(12)-Q-GlnR peptide
分子名称: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.07 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7SRV
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BU of 7srv by Molmil
Metal dependent activation of Plasmodium falciparum M17 aminopeptidase (inactive form), spacegroup P22121
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Webb, C.T, McGowan, S.
登録日2021-11-08
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A metal ion-dependent conformational switch modulates activity of the Plasmodium M17 aminopeptidase.
J.Biol.Chem., 298, 2022
7TF6
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BU of 7tf6 by Molmil
S. aureus GS(12)-Q-GlnR peptide
分子名称: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.15 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TFC
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BU of 7tfc by Molmil
B. subtilis GS(14)-Q-GlnR peptide
分子名称: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (1.96 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TDV
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BU of 7tdv by Molmil
Crystal structure of S. aureus glutamine synthetase in Met-Sox-P/ADP transition state complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
著者Schumacher, M.A.
登録日2022-01-03
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
6V8W
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BU of 6v8w by Molmil
CDYL2 chromodomain in complex with a synthetic peptide
分子名称: Chromodomain Y-like protein 2, IVA-PHE-ALA-PHE-5T3-SER-NH2, UNKNOWN ATOM OR ION
著者Dong, C, Tempel, W, James, L.I, Lamb, K.N, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2019-12-12
公開日2020-01-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
7T3M
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BU of 7t3m by Molmil
SARS-CoV-2 S (Spike Glycoprotein) D614G with Three (3) RBDs Up, Bound to Antibody 2-7 scFv, composite map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2-7 scFv, ...
著者Byrne, P.O, McLellan, J.S.
登録日2021-12-08
公開日2022-08-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
7SNQ
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BU of 7snq by Molmil
Hexamer HIV-1 CA in complex with CPSF6 peptide and IP6 ligand
分子名称: CHLORIDE ION, Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, ...
著者Bester, S.M, Kvaratskhelia, M.
登録日2021-10-28
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection.
Nat Commun, 13, 2022
6V6W
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BU of 6v6w by Molmil
Crystal structure of antibody 438-B11 DSS mutant (Cys98A-100aA) in complex with an uncleaved prefusion optimized (UFO) soluble BG505 trimer and Fab 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy chain, ...
著者Kumar, S, Wilson, I.A.
登録日2019-12-06
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite
Sci Adv, 6, 2020

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件を2024-08-28に公開中

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