8VK9
 
 | | Structure of UbV.d2.3 in complex with Ube2d2-S22R | | 分子名称: | GLYCEROL, Ubiquitin variant D2.3, Ubiquitin-conjugating enzyme E2 D2 | | 著者 | Middleton, A.J. | | 登録日 | 2024-01-08 | | 公開日 | 2024-09-25 | | 最終更新日 | 2024-12-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and biophysical characterisation of ubiquitin variants that inhibit the ubiquitin conjugating enzyme Ube2d2.
Febs J., 291, 2024
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8SYC
 | | Crystal structure of PDE3B in complex with GSK4394835A | | 分子名称: | MAGNESIUM ION, [3-[(4,7-dimethoxyquinolin-2-yl)carbonylamino]-5-[methyl-(phenylmethyl)carbamoyl]phenyl]-oxidanyl-oxidanylidene-boron, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B | | 著者 | Concha, N.O, Nolte, R. | | 登録日 | 2023-05-25 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library.
J.Med.Chem., 67, 2024
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8T1M
 | | Novel Domain of Unknown Function Solved with AlphaFold | | 分子名称: | DUF1842 domain-containing protein | | 著者 | Miller, J.E, Agdanowski, M.P, Cascio, D, Sawaya, M.R, Yeates, T.O. | | 登録日 | 2023-06-02 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography.
Acta Crystallogr D Struct Biol, 80, 2024
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8IVL
 | | FABP7 complexed with Cholesterol | | 分子名称: | CHOLESTEROL, Fatty acid-binding protein, brain | | 著者 | Wei, P.C, Zhao, K, Yin, L. | | 登録日 | 2023-03-28 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
J.Cell Biol., 223, 2024
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8BA0
 | | Drosophila melanogaster complex I in the Twisted state (Dm2) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | | 著者 | Agip, A.N.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | | 登録日 | 2022-10-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
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8IVF
 | | FABP7 complexed with 25-HC | | 分子名称: | 25-HYDROXYCHOLESTEROL, Fatty acid-binding protein, brain | | 著者 | Wei, P.C, Zhao, K, Yin, L. | | 登録日 | 2023-03-27 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
J.Cell Biol., 223, 2024
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8B9Z
 | | Drosophila melanogaster complex I in the Active state (Dm1) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | | 登録日 | 2022-10-10 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
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4WBH
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4WDI
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6M14
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8VJT
 | | Structure of the poly-UG quadruplex (GUGUGU)4 | | 分子名称: | POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*U)-3'), SODIUM ION | | 著者 | Bingman, C.A, Montemayor, E.J, Roschdi, S, Nomura, Y, Butcher, S.E. | | 登録日 | 2024-01-08 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.052 Å) | | 主引用文献 | Self-assembly and condensation of intermolecular poly(UG) RNA quadruplexes.
Nucleic Acids Res., 52, 2024
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6M0Q
 | | Hydroxylamine oxidoreductase from Nitrosomonas europaea | | 分子名称: | Aerobic hydroxylamine oxidoreductase, DI(HYDROXYETHYL)ETHER, HEME C, ... | | 著者 | Fujiwara, T, Fujimoto, Z, Nishigaya, Y, Yamazaki, T. | | 登録日 | 2020-02-22 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Juglone, a plant-derived 1,4-naphthoquinone, binds to hydroxylamine oxidoreductase and inhibits the electron transfer to cytochrome c 554.
Appl.Environ.Microbiol., 89, 2023
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6M0P
 | | Hydroxylamine oxidoreductase in complex with juglone | | 分子名称: | 5-hydroxynaphthalene-1,4-dione, Aerobic hydroxylamine oxidoreductase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Fujiwara, T, Fujimoto, Z, Nishigaya, Y, Yamazaki, T. | | 登録日 | 2020-02-22 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Juglone, a plant-derived 1,4-naphthoquinone, binds to hydroxylamine oxidoreductase and inhibits the electron transfer to cytochrome c 554.
Appl.Environ.Microbiol., 89, 2023
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4UUI
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8FU5
 | | Crystal structure of Fe-CAO1 in complex with piceatannol | | 分子名称: | BENZOIC ACID, Carotenoid oxygenase, FE (II) ION, ... | | 著者 | Kiser, P.D. | | 登録日 | 2023-01-16 | | 公開日 | 2024-08-07 | | 最終更新日 | 2025-04-09 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Spectroscopy and crystallography define carotenoid oxygenases as a new subclass of mononuclear non-heme Fe II enzymes.
J.Biol.Chem., 2025
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8FU2
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4URG
 | | Crystal Structure of GGDEF domain from T.maritima (active-like dimer) | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE | | 著者 | Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J. | | 登録日 | 2014-06-30 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
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6M2D
 | | MUL1-RING domain | | 分子名称: | Mitochondrial ubiquitin ligase activator of NFKB 1, SULFATE ION, ZINC ION | | 著者 | Lee, S.O, Ryu, K.S, Chi, S.-W. | | 登録日 | 2020-02-27 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | | 主引用文献 | MUL1-RING recruits the substrate, p53-TAD as a complex with UBE2D2-UB conjugate.
Febs J., 2022
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8V2U
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6M2C
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8V2M
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4URQ
 | | Crystal Structure of GGDEF domain (I site mutant) from T.maritima | | 分子名称: | DIGUANYLATE CYCLASE | | 著者 | Deepthi, A, Liew, C.W, Liang, Z.X, Swamianthan, K, Lescar, J. | | 登録日 | 2014-07-01 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
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1CSS
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4V07
 | | Dimeric pseudorabies virus protease pUL26N at 2.1 A resolution | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, UL26 | | 著者 | Zuehlsdorf, M, Werten, S, Palm, G.J, Hinrichs, W. | | 登録日 | 2014-09-11 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease
Plos Pathog., 11, 2015
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3NPZ
 | | Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL) | | 分子名称: | Prolactin, Prolactin receptor | | 著者 | Van Agthoven, J, England, P, Goffin, V, Broutin, I. | | 登録日 | 2010-06-29 | | 公開日 | 2010-10-06 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010
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