PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

---

6KDO	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y/M184V/F160M:DNA:lamivudine 5'-triphosphate ternary complex 分子名称: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2019-07-02 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.573 Å) 主引用文献 Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
7UJC	Raloxifene in Complex with Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutation 分子名称: Estrogen receptor, RALOXIFENE 著者 Hosfield, D.J, Greene, G.L, Fanning, S.W. 登録日 2022-03-30 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
7UJ8	Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with 4-Hydroxytamoxifen 分子名称: 4-HYDROXYTAMOXIFEN, Estrogen receptor 著者 Hosfield, D.J, Greene, G.L, Fanning, S.W. 登録日 2022-03-30 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.385 Å) 主引用文献 Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
7UJF	Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Methylated Lasofoxifene Derivative with Selective Estrogen Receptor Degrader Properties 分子名称: (5R,6S)-5-(4-{2-[(3S)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor 著者 Hosfield, D.J, Greene, G.L, Fanning, S.W. 登録日 2022-03-30 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
7UJW	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with a Methylated Lasofoxifene Derivative that Possesses Selective Estrogen Receptor Degrader Activities 分子名称: (5R,6S)-5-(4-{2-[(3S)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor 著者 Hosfield, D.J, Greene, G.L, Fanning, S.W. 登録日 2022-03-31 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
7UJM	Estrogen Receptor Alpha Ligand Binding Domain in Complex with a Methylated Lasofoxifene Derivative That Increases Receptor Resonance Time in the Nucleus of Breast Cancer Cells 分子名称: (5R,6S)-5-(4-{2-[(2R)-2-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor 著者 Hosfield, D.J, Greene, G.L, Fanning, S.W. 登録日 2022-03-31 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
7UJO	Estrogen Receptor Alpha Ligand Binding Domain in Complex with RU39411 分子名称: (9beta,11beta,17beta)-11-{4-[2-(dimethylamino)ethoxy]phenyl}estra-1,3,5(10)-triene-3,17-diol, Estrogen receptor, MAGNESIUM ION 著者 Hosfield, D.J, Greene, G.L, Fanning, S.W. 登録日 2022-03-31 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.449 Å) 主引用文献 Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
7UJY	Estrogen receptor alpha ligand binding domain Y537S mutant in complex with a methylated lasofoxifene derivative that enhances estrogen receptor alpha nuclear resonance time 分子名称: (5R,6S)-5-(4-{2-[(2R)-2-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor 著者 Hosfield, D.J, Greene, G.L, Fanning, S.W. 登録日 2022-03-31 公開日 2022-06-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
6KDM	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:entecavir 5'-triphosphate ternary complex 分子名称: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2019-07-02 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6KDN	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dGTP ternary complex 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2019-07-02 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6KDK	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2019-07-02 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6KDJ	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:lamivudine 5'-triphosphate ternary complex 分子名称: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2019-07-02 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
6I8T	THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH AN ISOINDOLINONE INHIBITOR 分子名称: (1~{R})-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1 著者 Casale, E, Papeo, G, Montagnoli, A. 登録日 2018-11-21 公開日 2019-05-01 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515. Acs Med.Chem.Lett., 10, 2019
7EQL	Crystal structure of (+)-pulegone reductase from Mentha piperita 分子名称: (+)-pulegone reductase 著者 Lin, W. 登録日 2021-05-03 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Functional Characterization and Structural Insights Into Stereoselectivity of Pulegone Reductase in Menthol Biosynthesis. Front Plant Sci, 12, 2021
7ETC	Crystal structure of AbHpaI-Zn-(4R)-KDGal complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: (4R,5R)-4,5,6-tris(oxidanyl)-2-oxidanylidene-hexanoic acid, 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETF	Crystal structure of AbHpaI-Mn-pyruvate-succinic semialdehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, 4-oxobutanoic acid, CALCIUM ION, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETB	Crystal structure of AbHpaI-Mn-pyruvate complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, MANGANESE (II) ION, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ET9	Crystal structure of AbHpaI-Zn-pyruvate complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, PYRUVIC ACID, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ET8	Crystal structure of thermostable AbHpaI, a class II metal dependent pyruvate aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETA	Crystal structure of AbHpaI-Co-pyruvate complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, COBALT (II) ION, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETG	Crystal structure of AbHpaI-Co-pyruvate-succinic semialdehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, 4-oxobutanoic acid, CALCIUM ION, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETD	Crystal structure of AbHpaI-Zn-(4S)-KDGlu complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 2-KETO-3-DEOXYGLUCONATE, 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETE	Crystal structure of AbHpaI-Mg-(4R)-KDGal complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: (4R,5R)-4,5,6-tris(oxidanyl)-2-oxidanylidene-hexanoic acid, 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETH	Crystal structure of AbHpaI-Zn-pyruvate-propionaldehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, PROPANAL, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021
7ETI	Crystal structure of AbHpaI-Zn-pyruvate-4-hydroxybenzaldehyde complex, Class II aldolase, HpaI from Acinetobacter baumannii 分子名称: 4-hydroxy-2-oxoheptanedioate aldolase, CALCIUM ION, P-HYDROXYBENZALDEHYDE, ... 著者 Watthaisong, P, Binlaeh, A, Jaruwat, A, Chaiyen, P, Chitnumsub, P, Maenpuen, S. 登録日 2021-05-12 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii. J.Biol.Chem., 297, 2021

<105106107108109110111112113114115116117118119120>