7M8H
 
 | | Structure of Memo1 C244S metal binding site mutant at 1.75A | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Boniecki, M.T, Uhlemann, E.E, Dmitriev, O.Y. | | 登録日 | 2021-03-29 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | MEMO1 binds iron and modulates iron homeostasis in cancer cells.
Elife, 13, 2024
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4P7X
 | | L-pipecolic acid-bound L-proline cis-4-hydroxylase | | 分子名称: | (2S)-piperidine-2-carboxylic acid, 2-OXOGLUTARIC ACID, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ... | | 著者 | Shomura, Y, Koketsu, K, Moriwaki, K, Hayashi, M, Mitsuhashi, S, Hara, R, Kino, K, Higuchi, Y. | | 登録日 | 2014-03-28 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Refined Regio- and Stereoselective Hydroxylation of l-Pipecolic Acid by Protein Engineering of l-Proline cis-4-Hydroxylase Based on the X-ray Crystal Structure.
Acs Synth Biol, 4, 2015
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1ABE
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4P7W
 | | L-proline-bound L-proline cis-4-hydroxylase | | 分子名称: | 2-OXOGLUTARIC ACID, COBALT (II) ION, L-proline cis-4-hydroxylase, ... | | 著者 | Shomura, Y, Koketsu, K, Moriwaki, K, Hayashi, M, Mitsuhashi, S, Hara, R, Kino, K, Higuchi, Y. | | 登録日 | 2014-03-28 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Refined Regio- and Stereoselective Hydroxylation of l-Pipecolic Acid by Protein Engineering of l-Proline cis-4-Hydroxylase Based on the X-ray Crystal Structure.
Acs Synth Biol, 4, 2015
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4PB4
 | | D-threo-3-hydroxyaspartate dehydratase H351A mutant complexed with 2-amino maleic acid | | 分子名称: | 2-amino maleic acid, D-threo-3-hydroxyaspartate dehydratase, MAGNESIUM ION, ... | | 著者 | Yasutake, Y, Matsumoto, Y, Wada, M. | | 登録日 | 2014-04-11 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate.
Appl.Microbiol.Biotechnol., 99, 2015
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7TAZ
 | | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor | | 分子名称: | 2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, Reverse transcriptase p51, Reverse transcriptase/ribonuclease H | | 著者 | Snyder, A.A, Risener, C.J, Kirby, K.A, Sarafianos, S.G. | | 登録日 | 2021-12-21 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor
To Be Published
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6L2F
 | | Crystal structure of a cupin protein (tm1459, H54AH58A mutant) in copper (Cu) substituted form | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, COPPER (II) ION, ... | | 著者 | Fujieda, N, Ichihashi, H, Nishikawa, Y, Kurisu, G, Itoh, S. | | 登録日 | 2019-10-03 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Cupin Variants as a Macromolecular Ligand Library for Stereoselective Michael Addition of Nitroalkanes.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6L2D
 | | Crystal structure of a cupin protein (tm1459) in copper (Cu) substituted form | | 分子名称: | COPPER (II) ION, Cupin_2 domain-containing protein | | 著者 | Fujieda, N, Ichihashi, H, Nishikawa, Y, Kurisu, G, Itoh, S. | | 登録日 | 2019-10-03 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.198 Å) | | 主引用文献 | Cupin Variants as a Macromolecular Ligand Library for Stereoselective Michael Addition of Nitroalkanes.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6L2E
 | | Crystal structure of a cupin protein (tm1459, H52A mutant) in copper (Cu) substituted form | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, Cupin_2 domain-containing protein | | 著者 | Fujieda, N, Ichihashi, H, Nishikawa, Y, Kurisu, G, Itoh, S. | | 登録日 | 2019-10-03 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.201 Å) | | 主引用文献 | Cupin Variants as a Macromolecular Ligand Library for Stereoselective Michael Addition of Nitroalkanes.
Angew.Chem.Int.Ed.Engl., 59, 2020
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4R20
 | | Zebra fish cytochrome P450 17A2 with Abiraterone | | 分子名称: | Abiraterone, Cytochrome P450 family 17 polypeptide 2, MERCURY (II) ION, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2014-08-08 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
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2YHG
 | | Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism | | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Hehemann, J.H, Marsters, C, Boraston, A.B. | | 登録日 | 2011-04-30 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Ab initio phasing of a nucleoside hydrolase-related hypothetical protein from Saccharophagus degradans that is associated with carbohydrate metabolism.
Proteins, 79, 2011
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2ZL8
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1Y54
 | | Crystal structure of the native class C beta-lactamase from Enterobacter cloacae 908R complexed with BRL42715 | | 分子名称: | (7R)-6-FORMYL-7-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC ACID, Beta-lactamase | | 著者 | Michaux, C, Charlier, P, Frere, J.-M, Wouters, J. | | 登録日 | 2004-12-02 | | 公開日 | 2005-03-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of BRL 42715, C6-(N1-Methyl-1,2,3-triazolylmethylene)penem, in Complex with Enterobactercloacae 908R beta-Lactamase: Evidence for a Stereoselective Mechanism from Docking Studies
J.Am.Chem.Soc., 127, 2005
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4R21
 | | Zebra fish cytochrome P450 17A2 with Progesterone | | 分子名称: | Cytochrome P450 family 17 polypeptide 2, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2014-08-08 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
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4R1Z
 | | Zebra fish cytochrome P450 17A1 with Abiraterone | | 分子名称: | Abiraterone, Cyp17a1 protein, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2014-08-08 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
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1B5E
 | | DCMP HYDROXYMETHYLASE FROM T4 | | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, PROTEIN (DEOXYCYTIDYLATE HYDROXYMETHYLASE) | | 著者 | Song, H.K, Sohn, S.H, Suh, S.W. | | 登録日 | 1999-01-06 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of deoxycytidylate hydroxymethylase from bacteriophage T4, a component of the deoxyribonucleoside triphosphate-synthesizing complex.
EMBO J., 18, 1999
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7KQ8
 | | Structure of iron bound MEMO1 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | | 著者 | Boniecki, M.T, Uhlemann, E.E, Dmitriev, O.Y. | | 登録日 | 2020-11-13 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | MEMO1 binds iron and modulates iron homeostasis in cancer cells.
Elife, 13, 2024
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7KR9
 | | Bifunctional enzyme GlmU bound to Zn(II) | | 分子名称: | ACETYL COENZYME *A, Bifunctional protein GlmU, CALCIUM ION, ... | | 著者 | Maher, M.J. | | 登録日 | 2020-11-19 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model.
Cell Rep, 38, 2022
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1B5D
 | | DCMP Hydroxymethylase from T4 (Intact) | | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, PROTEIN (DEOXYCYTIDYLATE HYDROXYMETHYLASE) | | 著者 | Song, H.K, Sohn, S.H, Suh, S.W. | | 登録日 | 1999-01-06 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of deoxycytidylate hydroxymethylase from bacteriophage T4, a component of the deoxyribonucleoside triphosphate-synthesizing complex.
EMBO J., 18, 1999
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4OZW
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1XK5
 | | Crystal structure of the m3G-cap-binding domain of snurportin1 in complex with a m3GpppG-cap dinucleotide | | 分子名称: | 2,2,7-TRIMETHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, snurportin-1 | | 著者 | Strasser, A, Dickmanns, A, Luehrmann, R, Ficner, R. | | 登録日 | 2004-09-27 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for m(3)G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1
Embo J., 24, 2005
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4PB3
 | | D-threo-3-hydroxyaspartate dehydratase H351A mutant | | 分子名称: | D-threo-3-hydroxyaspartate dehydratase, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Yasutake, Y, Matsumoto, Y, Wada, M. | | 登録日 | 2014-04-11 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insights into the substrate stereospecificity of D-threo-3-hydroxyaspartate dehydratase from Delftia sp. HT23: a useful enzyme for the synthesis of optically pure L-threo- and D-erythro-3-hydroxyaspartate.
Appl.Microbiol.Biotechnol., 99, 2015
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8JKU
 | | Ancestral imine reductase N559 | | 分子名称: | Ancestral imine reductase N559, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zhu, X.X, Zheng, G.W. | | 登録日 | 2023-06-01 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction.
Nat Commun, 15, 2024
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9CTE
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6V8T
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