7TAZ

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor

Summary for 7TAZ

• Entry DOI: 10.2210/pdb7taz/pdb
• Descriptor: Reverse transcriptase/ribonuclease H, Reverse transcriptase p51, 2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, ... (4 entities in total)
• Functional Keywords: reverse transcriptase, hiv-1, polymerase, nnrti, vm-1500, elsulfavirine, viral protein, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 2
• Total formula weight: 114659.00

Authors

Snyder, A.A.,Risener, C.J.,Kirby, K.A.,Sarafianos, S.G. (deposition date: 2021-12-21, release date: 2023-04-12, Last modification date: 2023-10-25)

• Primary citation: Snyder, A.A.,Risener, C.J.,Kirby, K.A.,Stefan, S.G.; Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)