PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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7LNL	Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem 分子名称: (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC 著者 Furey, I, Palzkill, T, Sankaran, B, Hu, L, Prasad, B.V.V. 登録日 2021-02-07 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 beta-lactamase. J.Biol.Chem., 296, 2021
2VCT	Glutathione transferase A2-2 in complex with delta-4-andostrene-3-17- dione 分子名称: 4-ANDROSTENE-3-17-DIONE, GLUTATHIONE S-TRANSFERASE A2 著者 Tars, K, Olin, B, Mannervik, B. 登録日 2007-09-27 公開日 2008-10-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for Featuring of Steroid Isomerase Activity in Alpha Class Glutathione Transferases. J.Mol.Biol., 397, 2010
7LHE	Structure of full-length IP3R1 channel reconstituted into lipid nanodisc in the apo-state 分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION 著者 Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. 登録日 2021-01-22 公開日 2021-06-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of type 1 IP3R channel in a lipid bilayer Commun Biol, 4, 2021
7LPS	Crystal structure of DDB1-CRBN-ALV1 complex bound to Helios (IKZF2 ZF2) 分子名称: 3-[3-[[1-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2,5-bis(oxidanylidene)pyrrol-3-yl]amino]phenyl]-~{N}-(3-chloranyl-4-methyl-phenyl)propanamide, DNA damage-binding protein 1, Protein cereblon, ... 著者 Nowak, R.P, Fischer, E.S. 登録日 2021-02-12 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.78 Å) 主引用文献 Acute pharmacological degradation of Helios destabilizes regulatory T cells. Nat.Chem.Biol., 17, 2021
8UXX	Arp2/3 branch junction complex, BeFx state 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Chavali, S.S, Chou, S.Z, Sindelar, C.V. 登録日 2023-11-11 公開日 2024-01-31 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
1O6V	Internalin (INLA, Listeria monocytogenes) - functional domain, uncomplexed 分子名称: CALCIUM ION, INTERNALIN A 著者 Schubert, W.-D, Urbanke, C, Ziehm, T, Beier, V, Machner, M.P, Domann, E, Wehland, J, Chakraborty, T, Heinz, D.W. 登録日 2002-10-16 公開日 2002-12-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of Internalin, a Major Invasion Protein of Listeria Monocytogenes, in Complex with its Human Receptor E-Cadherin Cell(Cambridge,Mass.), 111, 2002
7LHF	Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state 分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION 著者 Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. 登録日 2021-01-22 公開日 2021-06-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Cryo-EM structure of type 1 IP3R channel in a lipid bilayer Commun Biol, 4, 2021
5EIR	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, SULFATE ION, ... 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-10-30 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
8U7V	Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by GTP, ATP, IMP, and NAD+, interface-centered 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Calise, S.J, Kollman, J.M. 登録日 2023-09-15 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
2VLK	The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain 分子名称: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... 著者 Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y. 登録日 2008-01-15 公開日 2008-01-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain Immunity, 28, 2008
1ODS	Cephalosporin C deacetylase from Bacillus subtilis 分子名称: CEPHALOSPORIN C DEACETYLASE, CHLORIDE ION, MAGNESIUM ION 著者 Vincent, F, Charnock, S.J, Verschueren, K.H.G, Turkenburg, J.P, Scott, D.J, Offen, W.A, Roberts, S, Pell, G, Gilbert, H.J, Brannigan, J.A, Davies, G.J. 登録日 2003-02-20 公開日 2003-07-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multifunctional Xylooligosaccharide/Cephalosporin C Deacetylase Revealed by the Hexameric Structure of the Bacillus Subtilis Enzyme at 1.9A Resolution J.Mol.Biol., 330, 2003
4NAA	Crystal structure of UVB photoreceptor UVR8 from Arabidopsis thaliana and UV-induced structural changes at 120K 分子名称: MAGNESIUM ION, Ultraviolet-B receptor UVR8 著者 Yang, X, Zeng, X, Ren, Z, Zhao, K.H. 登録日 2013-10-22 公開日 2016-10-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Dynamic Crystallography Reveals Early Signalling Events in Ultraviolet Photoreceptor UVR8. Nat Plants, 1, 2015
4NBA	Carbazole-bound oxygenase with Ile262 replaced by Val and ferredoxin complex of carbazole 1,9a-dioxygenase 分子名称: 9H-CARBAZOLE, FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Ashikawa, Y, Usami, Y, Inoue, K, Nojiri, H. 登録日 2013-10-23 公開日 2014-03-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of the divergent oxygenation reactions catalyzed by the rieske nonheme iron oxygenase carbazole 1,9a-dioxygenase. Appl.Environ.Microbiol., 80, 2014
4IN4	Crystal structure of cpd 15 bound to Keap1 Kelch domain 分子名称: 2-({5-[(2,4-dimethylphenyl)sulfonyl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide, Kelch-like ECH-associated protein 1, PHOSPHATE ION 著者 Silvian, L, Marcotte, D. 登録日 2013-01-03 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism. Bioorg.Med.Chem., 21, 2013
4NBS	The structure of aIF2gamma subunit H20F from archaeon Sulfolobus solfataricus complexed with GDPCP 分子名称: FORMIC ACID, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... 著者 Kravchenko, O.V, Nikonov, O.S, Arhipova, V.I, Stolboushkina, E.A, Gabdulkhakov, A.G, Nikulin, A.D, Garber, M.B, Nikonov, S.V. 登録日 2013-10-23 公開日 2014-10-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.305 Å) 主引用文献 The structure of aIF2gamma subunit H20F from archaeon Sulfolobus solfataricus complexed with GDPCP To be Published
5ENL	INHIBITION OF ENOLASE: THE CRYSTAL STRUCTURES OF ENOLASE-CA2+-PHOSPHOGLYCERATE AND ENOLASE-ZN2+-PHOSPHOGLYCOLATE COMPLEXES AT 2.2-ANGSTROMS RESOLUTION 分子名称: 2-PHOSPHOGLYCERIC ACID, CALCIUM ION, ENOLASE 著者 Lebioda, L, Stec, B. 登録日 1990-11-13 公開日 1992-04-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Inhibition of enolase: the crystal structures of enolase-Ca2(+)- 2-phosphoglycerate and enolase-Zn2(+)-phosphoglycolate complexes at 2.2-A resolution. Biochemistry, 30, 1991
3G5H	Crystallographic analysis of cytochrome P450 cyp121 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Belin, P, Le Du, M.H, Gondry, M. 登録日 2009-02-05 公開日 2009-04-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
8U7M	Human retinal variant phosphomimetic IMPDH1(595)-S477D free octamer bound by GTP, ATP, IMP, and NAD+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... 著者 Calise, S.J, Kollman, J.M. 登録日 2023-09-15 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly. J.Cell Biol., 223, 2024
4MTW	Thermolysin in complex with UBTLN36 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Krimmer, S.G, Heine, A, Klebe, G. 登録日 2013-09-20 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Methyl, Ethyl, Propyl, Butyl: Futile But Not for Water, as the Correlation of Structure and Thermodynamic Signature Shows in a Congeneric Series of Thermolysin Inhibitors. Chemmedchem, 4, 2014
2VBM	Tailspike protein of bacteriophage Sf6 complexed with tetrasaccharide 分子名称: MAGNESIUM ION, MANGANESE (II) ION, PHOSPHATE ION, ... 著者 Mueller, J.J, Barbirz, S, Freiberg, A, Seckler, R, Heinemann, U. 登録日 2007-09-14 公開日 2008-04-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Intersubunit Active Site between Supercoiled Parallel Beta Helices in the Trimeric Tailspike Endorhamnosidase of Shigella Flexneri Phage Sf6. Structure, 16, 2008
2V2T	X-ray structure of a NF-kB p50-RelB-DNA complex 分子名称: 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3', NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT, TRANSCRIPTION FACTOR RELB 著者 Moorthy, A.K, Huang, D.B, Wang, V.Y, Vu, D, Ghosh, G. 登録日 2007-06-07 公開日 2007-07-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 X-Ray Structure of a NF-kappaB p50/Relb/DNA Complex Reveals Assembly of Multiple Dimers on Tandem kappaB Sites. J.Mol.Biol., 373, 2007
7RF9	O2-, PLP-dependent desaturase Plu4 intermediate-bound enzyme 分子名称: (2E)-5-carbamimidamido-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}pentanoic acid, 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, ... 著者 Hoffarth, E.R, Ryan, K.S. 登録日 2021-07-13 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.926 Å) 主引用文献 A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc.Natl.Acad.Sci.USA, 118, 2021
2V6L	Molecular Model of a Type III Secretion System Needle 分子名称: MXIH 著者 Deane, J.E, Roversi, P, Cordes, F.S, Johnson, S, Kenjale, R, Daniell, S, Booy, F, Picking, W.L, Picking, W.D, Blocker, A.J, Lea, S.M. 登録日 2007-07-19 公開日 2007-07-31 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Molecular model of a type III secretion system needle: Implications for host-cell sensing. Proc. Natl. Acad. Sci. U.S.A., 103, 2006
4IDD	Structure of the Fragaria x ananassa enone oxidoreductase in complex with NADPH and EHMF 分子名称: (2R)-2-ethyl-4-hydroxy-5-methylfuran-3(2H)-one, 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Schiefner, A, Skerra, A. 登録日 2012-12-12 公開日 2013-04-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for the enzymatic formation of the key strawberry flavor compound 4-hydroxy-2,5-dimethyl-3(2H)-furanone J.Biol.Chem., 288, 2013
3FXT	Crystal structure of the N-terminal domain of human NUDT6 分子名称: GLYCEROL, Nucleoside diphosphate-linked moiety X motif 6 著者 Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Siponen, M.I, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC) 登録日 2009-01-21 公開日 2009-03-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the N-terminal domain of human NUDT6 To be Published

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