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6ST6
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BU of 6st6 by Molmil
Crystal Structure of Domain Swapped Trp Repressor V58I Variant
分子名称: ISOPROPYL ALCOHOL, Trp operon repressor
著者Sprenger, J, Lawson, C.L, Carey, J, Drouard, F, von Wachenfeldt, C, Schulz, A, Linse, S, Lo Leggio, L.
登録日2019-09-10
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan.
Acta Crystallogr.,Sect.F, 77, 2021
6SCX
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BU of 6scx by Molmil
Crystal structure of the catalytic domain of human NUDT12 in complex with 7-methyl-guanosine-5'-triphosphate
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CADMIUM ION, Peroxisomal NADH pyrophosphatase NUDT12
著者McCarthy, A.A, Chen, K.M, Wu, H, Li, L, Homolka, D, Gos, P, Fleury-Olela, F, Pillai, R.S.
登録日2019-07-25
公開日2020-01-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.
Cell Rep, 29, 2019
6SIP
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BU of 6sip by Molmil
Fragment AZ-011 binding at the p53pT387/14-3-3 sigma interface
分子名称: 14-3-3 protein sigma, 7-methoxy-1-benzothiophene-2-carboximidamide, CHLORIDE ION, ...
著者Leysen, S, Wolter, M, Guillory, X, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C.
登録日2019-08-10
公開日2020-06-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.600447 Å)
主引用文献Fragment-based Differential Targeting of PPI Stabilizer Interfaces.
J.Med.Chem., 63, 2020
6JIZ
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BU of 6jiz by Molmil
Apo structure of an imine reductase at 1.76 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, 3-ethylheptane, 6-phosphogluconate dehydrogenase NAD-binding protein, ...
著者Li, H, Wu, L, Zheng, G.W, Zhou, J.H.
登録日2019-02-24
公開日2020-02-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.763 Å)
主引用文献Apo structure of an imine reductase at 1.76 Angstrom resolution
To Be Published
6JP6
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BU of 6jp6 by Molmil
The X-ray structure of yeast tRNA methyltransferase complex of Trm7 and Trm734 essential for 2'-O-methylation at the first position of anticodon in specific tRNAs
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, tRNA (cytidine(34)/guanosine(34)-2'-O)-methyltransferase, ...
著者Hirata, A, Okada, K, Yoshii, K, Shiraisi, H, Saijo, S, Yonezawa, K, Sihimzu, N, Hori, H.
登録日2019-03-26
公開日2019-10-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.
Nucleic Acids Res., 47, 2019
6SCG
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BU of 6scg by Molmil
Structure of AdhE form 1
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aldehyde-alcohol dehydrogenase, ...
著者Lovering, A.L, Bragginton, E.
登録日2019-07-24
公開日2020-08-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献High-resolution structure of the alcohol dehydrogenase domain of the bifunctional bacterial enzyme AdhE.
Acta Crystallogr.,Sect.F, 76, 2020
6SCZ
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BU of 6scz by Molmil
Mycobacterium tuberculosis alanine racemase inhibited by DCS
分子名称: (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者de Chiara, C, Purkiss, A, Prosser, G, Homsak, M, de Carvalho, L.P.S.
登録日2019-07-26
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition.
Nat.Chem.Biol., 16, 2020
6JQH
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BU of 6jqh by Molmil
Crystal structure of MaDA
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MaDA
著者Du, X.X, Lei, X.G.
登録日2019-03-31
公開日2020-04-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis.
Nat.Chem., 12, 2020
6SKY
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BU of 6sky by Molmil
FAT and kinase domain of CtTel1
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1
著者Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P.
登録日2019-08-16
公開日2019-10-30
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
6SN1
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BU of 6sn1 by Molmil
Crystal structure of the human INTS13-INTS14 complex
分子名称: Integrator complex subunit 13, Integrator complex subunit 14, SULFATE ION
著者Jonas, S, Sabath, K, Staeubli, M.L.
登録日2019-08-23
公開日2020-07-22
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.
Nat Commun, 11, 2020
6SNI
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BU of 6sni by Molmil
Cryo-EM structure of nanodisc reconstituted yeast ALG6 in complex with 6AG9 Fab
分子名称: 6AG9-Fab heavy chain, 6AG9-Fab light chain, CHOLESTEROL HEMISUCCINATE, ...
著者Bloch, J.S, Pesciullesi, G, Boilevin, J, Nosol, K, Irobalieva, R.N, Darbre, T, Aebi, M, Kossiakoff, A.A, Reymond, J.L, Locher, K.P.
登録日2019-08-24
公開日2020-03-11
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and mechanism of the ER-based glucosyltransferase ALG6.
Nature, 579, 2020
6SYC
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BU of 6syc by Molmil
Crystal structure of the lysozyme in presence of bromophenol blue at pH 6.5
分子名称: CHLORIDE ION, IMIDAZOLE, Lysozyme, ...
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2019-09-27
公開日2020-09-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Lysozyme crystals dyed with bromophenol blue: where has the dye gone?
Acta Crystallogr D Struct Biol, 76, 2020
6SD5
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BU of 6sd5 by Molmil
Structure of the RBM2 inner ring of Salmonella flagella MS-ring protein FliF with 22-fold symmetry applied
分子名称: Flagellar M-ring protein
著者Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M.
登録日2019-07-26
公開日2020-03-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation.
Nat Microbiol, 5, 2020
6SFA
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BU of 6sfa by Molmil
Trypanosoma cruzi farnesyl diphosphate synthase apo structure with Mn ions
分子名称: Farnesyl diphosphate synthase, MANGANESE (II) ION, SULFATE ION
著者Magari, F, Heine, A, Klebe, G.
登録日2019-08-01
公開日2020-08-26
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Trypanosoma cruzi farnesyl diphosphate synthase apo structure with Mn ions
To Be Published
6RUU
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BU of 6ruu by Molmil
Pseudokinase domain of human IRAK3
分子名称: GLYCEROL, Interleukin-1 receptor-associated kinase 3, MERCURY (II) ION, ...
著者Lange, S.M, Kulathu, Y, Cohen, P.
登録日2019-05-29
公開日2020-09-09
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation.
Structure, 29, 2021
6I09
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BU of 6i09 by Molmil
Crystal structure of RlpA SPOR domain from Pseudomonas aeruginosa in complex with denuded glycan obtained by soaking
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-beta-D-glucopyranoside, Endolytic peptidoglycan transglycosylase RlpA
著者Alcorlo, M, Hermoso, J.A.
登録日2018-10-25
公開日2019-11-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division.
Nat Commun, 10, 2019
6I0A
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BU of 6i0a by Molmil
Crystal structure of RlpA SPOR domain from Pseudomonas aeruginosa in complex with nuded glycan obtained by co-crystallization
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-beta-D-glucopyranoside, Endolytic peptidoglycan transglycosylase RlpA
著者Alcorlo, M, Hermoso, J.A.
登録日2018-10-25
公開日2019-11-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division.
Nat Commun, 10, 2019
3BHO
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BU of 3bho by Molmil
Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im with Ap4A
分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Cleavage and polyadenylation specificity factor subunit 5
著者Coseno, M, Doublie, S.
登録日2007-11-28
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the 25 kDa subunit of human cleavage factor Im.
Nucleic Acids Res., 36, 2008
6S47
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BU of 6s47 by Molmil
Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1
分子名称: 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V.
登録日2019-06-26
公開日2019-07-24
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
Nucleic Acids Res., 47, 2019
6HI0
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BU of 6hi0 by Molmil
Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine
分子名称: 1,2-ETHANEDIOL, 5'-O-(N-(L-seryl)-Sulfamoyl)uridine, CALCIUM ION, ...
著者Pang, L, De Graef, S, Weeks, S.D, Strelkov, S.V.
登録日2018-08-29
公開日2019-12-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
6HE3
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BU of 6he3 by Molmil
Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine
分子名称: 1,2-ETHANEDIOL, 5'-O-(N-(L-seryl)-sulfamoyl)cytidine, SODIUM ION, ...
著者Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D.
登録日2018-08-20
公開日2019-12-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
6RGQ
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BU of 6rgq by Molmil
Human 20S Proteasome
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Toste Rego, A, da Fonseca, P.C.A.
登録日2019-04-17
公開日2019-09-04
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Characterization of Fully Recombinant Human 20S and 20S-PA200 Proteasome Complexes.
Mol.Cell, 76, 2019
6HM8
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BU of 6hm8 by Molmil
Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of enterovirus-D68 (fusion protein)
分子名称: Genome polyprotein, Golgi resident protein GCP60
著者Klima, M, Boura, E.
登録日2018-09-12
公開日2019-07-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.277 Å)
主引用文献Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites.
Plos Pathog., 15, 2019
6HHY
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BU of 6hhy by Molmil
Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine
分子名称: 1,2-ETHANEDIOL, 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine, CALCIUM ION, ...
著者Pang, L, De Graef, S, Weeks, S.D, Strelkov, S.V.
登録日2018-08-29
公開日2019-12-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
6R70
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Endogeneous native human 20S proteasome
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Schmidli, C, Albiez, S, Rima, L, Righetto, R, Mohammed, I, Oliva, P, Kovacik, L, Stahlberg, H, Braun, T.
登録日2019-03-28
公開日2019-07-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Microfluidic protein isolation and sample preparation for high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 116, 2019

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件を2025-07-09に公開中

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