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5X57
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Structure of GAR domain of ACF7
分子名称: Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, NICKEL (II) ION
著者Yang, F, Wang, T, Zhang, Y, Wu, X.Y.
登録日2017-02-15
公開日2017-07-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics.
Nat Commun, 8, 2017
2MOT
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BU of 2mot by Molmil
Backbone Structure of Actin Depolymerizing Factor (ADF) of Toxoplasma gondii Based on Prot3DNMR Approach
分子名称: Actin depolymerizing factor ADF
著者Kumar, D, Raikwal, N, Raval, I, Jaiswal, N, Shukla, V, Arora, A.
登録日2014-05-05
公開日2015-05-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Prot3DNMR: A Simple and Swift Strategy for Backbone Structure Determination of Proteins by NMR
To be Published
7O7I
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BU of 7o7i by Molmil
Crystal structure of the human HIPK3 kinase domain
分子名称: 1,2-ETHANEDIOL, Homeodomain-interacting protein kinase 3
著者Kaltheuner, I.H, Anand, K, Geyer, M.
登録日2021-04-13
公開日2021-11-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.
Nat Commun, 12, 2021
4LHX
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BU of 4lhx by Molmil
Crystal structure of nucleotide-free Rab8:Rabin8
分子名称: Rab-3A-interacting protein, Ras-related protein Rab-8A, SULFATE ION
著者Guo, Z, Hou, X.M, Goody, R.S, Itzen, A.
登録日2013-07-01
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
5LJ6
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BU of 5lj6 by Molmil
Structure of Aggregatibacter actinomycetemcomitans MacB bound to ATPyS (P6522)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Macrolide export ATP-binding/permease protein MacB
著者Crow, A.
登録日2016-07-18
公開日2017-11-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LJ7
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BU of 5lj7 by Molmil
Structure of Aggregatibacter actinomycetemcomitans MacB bound to ATP (P21)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Macrolide export ATP-binding/permease protein MacB
著者Crow, A.
登録日2016-07-18
公開日2017-11-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5YRN
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BU of 5yrn by Molmil
Structure of RIP2 CARD domain
分子名称: Receptor-interacting serine/threonine-protein kinase 2
著者Wu, B, Gong, Q.
登録日2017-11-09
公開日2018-11-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of RIP2 activation and signaling.
Nat Commun, 9, 2018
5YZ0
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BU of 5yz0 by Molmil
Cryo-EM Structure of human ATR-ATRIP complex
分子名称: ATR-interacting protein, Serine/threonine-protein kinase ATR
著者Rao, Q, Liu, M, Tian, Y, Wu, Z, Wang, H, Wang, J, Xu, Y.
登録日2017-12-11
公開日2018-01-31
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM structure of human ATR-ATRIP complex.
Cell Res., 28, 2018
5ENH
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BU of 5enh by Molmil
Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with compound-12 N11528 (SGC - Diamond I04-1 fragment screening)
分子名称: PH-interacting protein, ~{N}-[(2,6-dimethoxyphenyl)methyl]ethanamide
著者Krojer, T, Talon, R, Collins, P, Bradley, A, Cox, O, Szykowska, A, Burgess-Brown, N, Brennan, P, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F, Structural Genomics Consortium (SGC)
登録日2015-11-09
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain.
Chem Sci, 7, 2016
5ENI
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BU of 5eni by Molmil
Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with compound-13 N11537 (SGC - Diamond I04-1 fragment screening)
分子名称: PH-interacting protein, ~{N}-[[2,6-bis(chloranyl)phenyl]methyl]-2-oxidanyl-ethanamide
著者Krojer, T, Talon, R, Collins, P, Bradley, A, Cox, O, Szykowska, A, Burgess-Brown, N, Brennan, P, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F, Structural Genomics Consortium (SGC)
登録日2015-11-09
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain.
Chem Sci, 7, 2016
3M9V
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BU of 3m9v by Molmil
X-ray Structure of a KijD3 in Complex with dTDP
分子名称: FAD-dependent oxidoreductase, THYMIDINE-5'-DIPHOSPHATE
著者Bruender, N.A, Thoden, J.B, Holden, H.M.
登録日2010-03-22
公開日2010-04-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray structure of kijd3, a key enzyme involved in the biosynthesis of D-kijanose.
Biochemistry, 49, 2010
4WDC
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BU of 4wdc by Molmil
High-resolution crystal structure of water-soluble FraC (mutation F16P)
分子名称: Fragaceatoxin C
著者Caaveiro, J.M.M, Morante, K, Tsumoto, K.
登録日2014-09-08
公開日2015-03-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献A Pore-Forming Toxin Requires a Specific Residue for Its Activity in Membranes with Particular Physicochemical Properties
J.Biol.Chem., 290, 2015
3VWI
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BU of 3vwi by Molmil
High resolution crystal structure of FraC in the monomeric form
分子名称: AMMONIUM ION, CHLORIDE ION, Fragaceatoxin C, ...
著者Tanaka, K, Morante, K, Caaveiro, J.M.M, Gonzalez-Manas, J.M, Tsumoto, K.
登録日2012-08-23
公開日2013-08-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
6LUF
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BU of 6luf by Molmil
Trans-acting mutant Y290A of the central AAA+ domain of the flagellar regulatory protein FlrC
分子名称: ADENOSINE-5'-DIPHOSPHATE, Flagellar regulatory protein C
著者Dasgupta, J, Chakraborty, S.
登録日2020-01-27
公開日2020-03-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Oligomerization of flagellar regulatory protein FlrC is essential for cis-mediated ATP binding while c-di-GMP prefers its monomeric state
To Be Published
4NQ0
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BU of 4nq0 by Molmil
Structural insights into yeast histone chaperone Hif1: a scaffold protein recruiting protein complexes to core histones
分子名称: HAT1-interacting factor 1
著者Liu, H, Zhang, M, He, W, Zhu, Z, Teng, M, Gao, Y, Niu, L.
登録日2013-11-23
公開日2014-07-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into yeast histone chaperone Hif1: a scaffold protein recruiting protein complexes to core histones
Biochem.J., 462, 2014
8JT3
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BU of 8jt3 by Molmil
Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Arg
分子名称: (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-arginine, ACETATE ION, CrmG, ...
著者Su, K, Zhang, Y, Xu, J, Liu, J.
登録日2023-06-21
公開日2023-08-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Co-crystal structure provides insights on transaminase CrmG recognition amino donor L-Arg.
Biochem.Biophys.Res.Commun., 675, 2023
1WS1
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BU of 1ws1 by Molmil
Structure analysis of peptide deformylase from Bacillus cereus
分子名称: ACTINONIN, NICKEL (II) ION, Peptide deformylase 1
著者Moon, J.H, Park, J.K, Kim, E.E.
登録日2004-10-29
公開日2005-09-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure analysis of peptide deformylase from Bacillus cereus
Proteins, 61, 2005
6OVM
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BU of 6ovm by Molmil
Crystal Structure of the Pseudomonas capeferrum Anti-sigma Regulator PupR C-terminal Cell-surface Signaling Domain in Complex with the Outer Membrane Transporter PupB N-terminal Signaling Domain (SeMet)
分子名称: Ferric-pseudobactin BN7/BN8 receptor, L(+)-TARTARIC ACID, Siderophore-interacting protein
著者Jensen, J.L, Colbert, C.L.
登録日2019-05-08
公開日2020-03-04
最終更新日2020-05-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of cell-surface signaling by a conserved sigma regulator in Gram-negative bacteria.
J.Biol.Chem., 295, 2020
5BT1
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BU of 5bt1 by Molmil
histone chaperone Hif1 playing with histone H2A-H2B dimer
分子名称: HAT1-interacting factor 1, Histone H2A.1, Histone H2B.1
著者Liu, H, Zhang, M, Gao, Y, Teng, M, Niu, L.
登録日2015-06-02
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer
Structure, 24, 2016
2RT5
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BU of 2rt5 by Molmil
Structural insights into the recruitment of SMRT by the co-repressor SHARP under phosphorylative regulation
分子名称: Msx2-interacting protein, peptide from Silencing mediator of retinoic acid and thyroid hormone receptor
著者Mikami, S, Kanaba, T, Mishima, M.
登録日2013-04-22
公開日2013-12-04
最終更新日2022-08-24
実験手法SOLUTION NMR
主引用文献Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.
Structure, 22, 2014
3A4S
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BU of 3a4s by Molmil
The crystal structure of the SLD2:Ubc9 complex
分子名称: NFATC2-interacting protein, SUMO-conjugating enzyme UBC9
著者Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M.
登録日2009-07-14
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
5COS
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BU of 5cos by Molmil
Crystal Structure of the Cytoplasmic Domain of the Pseudomonas putida Anti-sigma Factor PupR
分子名称: Siderophore-interacting protein
著者Jensen, J.L, Colbert, C.L.
登録日2015-07-20
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.019 Å)
主引用文献Mechanistic Implications of the Unique Structural Features and Dimerization of the Cytoplasmic Domain of the Pseudomonas Sigma Regulator, PupR.
Biochemistry, 54, 2015
1YSM
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BU of 1ysm by Molmil
NMR Structure of N-terminal domain (Residues 1-77) of Siah-Interacting Protein.
分子名称: Calcyclin-binding protein
著者Bhattacharya, S, Lee, Y.T, Michowski, W, Jastrzebska, B, Filipek, A, Kuznicki, J, Chazin, W.J.
登録日2005-02-08
公開日2005-07-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Modular Structure of SIP Facilitates Its Role in Stabilizing Multiprotein Assemblies.
Biochemistry, 44, 2005
4WHN
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BU of 4whn by Molmil
Structure of toxin-activating acyltransferase (TAAT)
分子名称: ApxC, CITRIC ACID
著者Crow, A, Greene, N.P, Hughes, C, Koronakis, V.
登録日2014-09-23
公開日2015-06-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of a bacterial toxin-activating acyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
6OVK
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BU of 6ovk by Molmil
Crystal Structure of the Pseudomonas capeferrum Anti-sigma Regulator PupR C-terminal Cell-surface Signaling Domain in Complex with the Outer Membrane Transporter PupB N-terminal Signaling Domain
分子名称: Ferric-pseudobactin BN7/BN8 receptor, L(+)-TARTARIC ACID, Siderophore-interacting protein
著者Jensen, J.L, Colbert, C.L.
登録日2019-05-08
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献Structural basis of cell-surface signaling by a conserved sigma regulator in Gram-negative bacteria.
J.Biol.Chem., 295, 2020

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