4UZG
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![BU of 4uzg by Molmil](/molmil-images/mine/4uzg) | Crystal structure of group B streptococcus pilus 2b backbone protein SAK_1440 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, SURFACE PROTEIN SPB1 | 著者 | Malito, E, Cozzi, R, Bottomley, M.J. | 登録日 | 2014-09-05 | 公開日 | 2015-05-13 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Structure and assembly of group B streptococcus pilus 2b backbone protein. PLoS ONE, 10, 2015
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7CJD
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9FQJ
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![BU of 9fqj by Molmil](/molmil-images/mine/9fqj) | E3 ligase Cbl-b in complex with a carbamate scaffold inhibitor (compound 12) | 分子名称: | 2-cyclopropyl-6-methyl-~{N}-[3-[(6~{S})-6-methyl-2-oxidanylidene-1,3-oxazinan-6-yl]phenyl]pyrimidine-4-carboxamide, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ... | 著者 | Schimpl, M. | 登録日 | 2024-06-17 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.563 Å) | 主引用文献 | Accelerated Discovery of a Carbamate Scaffold Cbl-b Inhibitor using Generative Models and Structure-Based Drug Design To be published
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7CW3
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![BU of 7cw3 by Molmil](/molmil-images/mine/7cw3) | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | 登録日 | 2020-08-27 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CMD
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2B7T
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![BU of 2b7t by Molmil](/molmil-images/mine/2b7t) | Structure of ADAR2 dsRBM1 | 分子名称: | Double-stranded RNA-specific editase 1 | 著者 | Stefl, R, Xu, M, Skrisovska, L, Emeson, R.B, Allain, F.H.-T. | 登録日 | 2005-10-05 | 公開日 | 2006-03-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. Structure, 14, 2006
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7CW2
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![BU of 7cw2 by Molmil](/molmil-images/mine/7cw2) | Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 (subregion around icosahedral 5-fold vertex) | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | 登録日 | 2020-08-27 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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2B7V
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![BU of 2b7v by Molmil](/molmil-images/mine/2b7v) | Structure of ADAR2 dsRBM2 | 分子名称: | Double-stranded RNA-specific editase 1 | 著者 | Stefl, R, Xu, M, Skrisovska, L, Emeson, R.B, Allain, F.H.-T. | 登録日 | 2005-10-05 | 公開日 | 2006-03-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. Structure, 14, 2006
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9FQI
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![BU of 9fqi by Molmil](/molmil-images/mine/9fqi) | E3 ligase Cbl-b in complex with a lactam scaffold inhibitor (compound 7) | 分子名称: | 8-[3-[(4~{R})-4-methyl-2-oxidanylidene-piperidin-4-yl]phenyl]-3-[[(3~{S})-3-methylpiperidin-1-yl]methyl]-5-(trifluoromethyl)-1$l^{4},7,8-triazabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ... | 著者 | Schimpl, M. | 登録日 | 2024-06-17 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Accelerated Discovery of a Carbamate Scaffold Cbl-b Inhibitor using Generative Models and Structure-Based Drug Design To be published
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9FQH
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![BU of 9fqh by Molmil](/molmil-images/mine/9fqh) | E3 ligase Cbl-b in complex with a triazolone core inhibitor (compound 1) | 分子名称: | 8-[3-[3-methyl-1-(4-methyl-1,2,4-triazol-3-yl)cyclobutyl]phenyl]-3-[[(3~{S})-3-methylpiperidin-1-yl]methyl]-5-(trifluoromethyl)-1$l^{4},7,8-triazabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, E3 ubiquitin-protein ligase CBL-B, SODIUM ION, ... | 著者 | Schimpl, M. | 登録日 | 2024-06-17 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.786 Å) | 主引用文献 | Accelerated Discovery of a Carbamate Scaffold Cbl-b Inhibitor using Generative Models and Structure-Based Drug Design To be published
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9F7X
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7CW0
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![BU of 7cw0 by Molmil](/molmil-images/mine/7cw0) | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | 登録日 | 2020-08-27 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CVZ
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![BU of 7cvz by Molmil](/molmil-images/mine/7cvz) | Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | 登録日 | 2020-08-27 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CVY
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![BU of 7cvy by Molmil](/molmil-images/mine/7cvy) | Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124 | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | 登録日 | 2020-08-27 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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4V7G
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![BU of 4v7g by Molmil](/molmil-images/mine/4v7g) | Crystal Structure of Lumazine Synthase from Bacillus Anthracis | 分子名称: | 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION | 著者 | Morgunova, E, Illarionov, B, Saller, S, Popov, A, Sambaiah, T, Bacher, A, Cushman, M, Fischer, M, Ladenstein, R. | 登録日 | 2009-09-16 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase from Bacillus anthracis. Acta Crystallogr.,Sect.D, 66, 2010
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9FWX
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![BU of 9fwx by Molmil](/molmil-images/mine/9fwx) | Crystal structure of BRD4 BD1 with MEN1404BS. | 分子名称: | 3-methyl-~{N}-(2-phenylethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-amine, Bromodomain-containing protein 4 | 著者 | Bader, G, Kessler, D. | 登録日 | 2024-07-01 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Probing Protein-Ligand Methyl-pi Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups. J.Med.Chem., 2024
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7C5E
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![BU of 7c5e by Molmil](/molmil-images/mine/7c5e) | Crystal structure of Keap1 in complex with fumarate (FUM) | 分子名称: | ACETATE ION, FUMARIC ACID, Kelch-like ECH-associated protein 1, ... | 著者 | Padmanabhan, B, Unni, S, Deshmukh, P. | 登録日 | 2020-05-19 | 公開日 | 2020-08-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1. Febs J., 288, 2021
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7C60
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![BU of 7c60 by Molmil](/molmil-images/mine/7c60) | Crystal structure of Keap1 in complex with monoethyl fumarate (MEF) | 分子名称: | (~{Z})-4-ethoxy-4-oxidanylidene-but-2-enoic acid, ACETATE ION, Kelch-like ECH-associated protein 1, ... | 著者 | Padmanabhan, B, Unni, S, Deshmukh, P, Krishnappa, G. | 登録日 | 2020-05-21 | 公開日 | 2020-08-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1. Febs J., 288, 2021
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6YEF
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![BU of 6yef by Molmil](/molmil-images/mine/6yef) | 70S initiation complex with assigned rRNA modifications from Staphylococcus aureus | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... | 著者 | Fatkhullin, B, Golubev, A, Khusainov, I, Yusupova, G, Yusupov, M. | 登録日 | 2020-03-24 | 公開日 | 2021-01-27 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 angstrom resolution. Febs Lett., 594, 2020
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6YST
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![BU of 6yst by Molmil](/molmil-images/mine/6yst) | Structure of the P+9 ArfB-ribosome complex with P/E hybrid tRNA in the post-hydrolysis state | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | 登録日 | 2020-04-23 | 公開日 | 2020-08-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nat Commun, 11, 2020
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6YSS
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![BU of 6yss by Molmil](/molmil-images/mine/6yss) | Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | 登録日 | 2020-04-23 | 公開日 | 2020-08-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nat Commun, 11, 2020
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7O9K
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![BU of 7o9k by Molmil](/molmil-images/mine/7o9k) | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Valentin Gese, G, Hallberg, B.M. | 登録日 | 2021-04-16 | 公開日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun, 12, 2021
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7O9M
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![BU of 7o9m by Molmil](/molmil-images/mine/7o9m) | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Valentin Gese, G, Hallberg, B.M. | 登録日 | 2021-04-16 | 公開日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural basis for late maturation steps of the human mitoribosomal large subunit. Nat Commun, 12, 2021
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6YSU
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![BU of 6ysu by Molmil](/molmil-images/mine/6ysu) | Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | 登録日 | 2020-04-23 | 公開日 | 2020-08-19 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nat Commun, 11, 2020
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8EJI
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![BU of 8eji by Molmil](/molmil-images/mine/8eji) | |