PDB: 343 件ウェブページステータス検索Chemie searchBIRD

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2GEQ	Crystal Structure of a p53 Core Dimer Bound to DNA 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*CP*GP*TP*GP*AP*GP*CP*AP*TP*GP*CP*TP*CP*AP*C)-3', Cellular tumor antigen p53, ... 著者 Ho, W.C, Fitzgerald, M.X, Marmorstein, R. 登録日 2006-03-20 公開日 2006-05-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the p53 Core Domain Dimer Bound to DNA. J.Biol.Chem., 281, 2006
2CGA	BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION 分子名称: CHYMOTRYPSINOGEN A 著者 Wang, D, Bode, W, Huber, R. 登録日 1987-01-16 公開日 1987-04-16 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution. J.Mol.Biol., 185, 1985
3VGC	GAMMA-CHYMOTRYPSIN L-NAPHTHYL-1-ACETAMIDO BORONIC ACID ACID INHIBITOR COMPLEX 分子名称: GAMMA CHYMOTRYPSIN, L-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, SULFATE ION 著者 Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. 登録日 1997-05-01 公開日 1997-11-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
2GCH	REFINED CRYSTAL STRUCTURE OF GAMMA-CHYMOTRYPSIN AT 1.9 ANGSTROMS RESOLUTION 分子名称: GAMMA-CHYMOTRYPSIN A 著者 Cohen, G.H, Davies, D.R, Silverton, E.W. 登録日 1980-05-21 公開日 1980-07-09 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Refined crystal structure of gamma-chymotrypsin at 1.9 A resolution. Comparison with other pancreatic serine proteases. J.Mol.Biol., 148, 1981
2GCT	STRUCTURE OF GAMMA-CHYMOTRYPSIN IN THE RANGE PH 2.0 TO PH 10.5 SUGGESTS THAT GAMMA-CHYMOTRYPSIN IS A COVALENT ACYL-ENZYME ADDUCT AT LOW PH 分子名称: GAMMA-CHYMOTRYPSIN A, SULFATE ION, TETRAPEPTIDE ADDUCT 著者 Dixon, M.M, Matthews, B.W. 登録日 1990-09-04 公開日 1991-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH. Int.J.Biol.Macromol., 13, 1991
2H1L	The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex 分子名称: Cellular tumor antigen p53, Large T antigen, ZINC ION 著者 Lilyestrom, W, Klein, M.G, Chen, X.S. 登録日 2006-05-16 公開日 2006-09-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev., 20, 2006
4IBW	Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R in sequence-specific complex with DNA 分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), ... 著者 Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.791 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IBQ	Human p53 core domain with hot spot mutation R273C 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... 著者 Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IJT	Human p53 core domain with hot spot mutation R273H (form II) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cellular tumor antigen p53, ... 著者 Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-23 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IBS	Human p53 core domain with hot spot mutation R273H (form I) 分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, ZINC ION 著者 Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
2PCX	Crystal structure of p53DBD(R282Q) at 1.54-angstrom Resolution 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Tu, C, Shaw, G, Ji, X. 登録日 2007-03-30 公開日 2008-04-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Impact of low-frequency hotspot mutation R282Q on the structure of p53 DNA-binding domain as revealed by crystallography at 1.54 angstroms resolution. Acta Crystallogr.,Sect.D, 64, 2008
4IBT	Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Diskin-Posner, Y, Eldar, A, Rozenberg, H, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
2JET	Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin. 分子名称: CHYMOTRYPSINOGEN B CHAIN A, CHYMOTRYPSINOGEN B CHAIN B, CHYMOTRYPSINOGEN B CHAIN C 著者 Jelinek, B, Katona, G, Fodor, K, Venekei, I, Graf, L. 登録日 2007-01-22 公開日 2007-09-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Crystal Structure of a Trypsin-Like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin. Protein J., 27, 2008
2VYR	Structure of human MDM4 N-terminal domain bound to a single domain antibody 分子名称: HUMAN SINGLE DOMAIN ANTIBODY, MDM4 PROTEIN, SULFATE ION 著者 Yu, G.W, Vaysburd, M, Allen, M.D, Settanni, G, Fersht, A.R. 登録日 2008-07-28 公開日 2008-11-25 最終更新日 2013-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of Human Mdm4 N-Terminal Domain Bound to a Single-Domain Antibody. J.Mol.Biol., 385, 2009
2OCJ	Human p53 core domain in the absence of DNA 分子名称: P53 TUMOR SUPPRESSOR, ZINC ION 著者 Wang, Y, Rosengarth, A, Luecke, H. 登録日 2006-12-20 公開日 2007-03-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the human p53 core domain in the absence of DNA. Acta Crystallogr.,Sect.D, 63, 2007
2P52	mouse p53 DNA-binding domain in zinc-free oxidized state 分子名称: Cellular tumor antigen p53 著者 Kwon, E, Kim, D.Y, Suh, S.W, Kim, K.K. 登録日 2007-03-14 公開日 2008-01-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the mouse p53 core domain in zinc-free state. Proteins, 70, 2008
2QC3	Crystal structure of MCAT from Mycobacterium tuberculosis 分子名称: ACETIC ACID, Malonyl CoA-acyl carrier protein transacylase 著者 Li, Z, Huang, Y, Ge, J, Bartlam, M, Wang, H, Rao, Z. 登録日 2007-06-19 公開日 2007-08-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models. J.Mol.Biol., 371, 2007
2QEJ	Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... 著者 Ramsland, P.A, Willoughby, N, Trist, H.M, Farrugia, W, Hogarth, P.M, Fraser, J.D, Wines, B.D. 登録日 2007-06-26 公開日 2007-09-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1 Proc.Natl.Acad.Sci.Usa, 104, 2007
2IOO	Crystal structure of the mouse p53 core domain 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. 登録日 2006-10-10 公開日 2006-12-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallogr.,Sect.D, 62, 2006
4IBZ	Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation T284R 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... 著者 Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4IBU	Human p53 core domain with hot spot mutation R273C and second-site suppressor mutation T284R in sequence-specific complex with DNA 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cellular tumor antigen p53, ... 著者 Eldar, A, Rozenberg, H, Diskin-Posner, Y, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
2IOI	Crystal structure of the mouse p53 core domain at 1.55 A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ZINC ION 著者 Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. 登録日 2006-10-10 公開日 2006-12-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallogr.,Sect.D, 62, 2006
2IOM	Mouse p53 core domain soaked with 2-propanol 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ISOPROPYL ALCOHOL, ... 著者 Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. 登録日 2006-10-10 公開日 2006-12-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2P8O	Crystal Structure of a Benzohydroxamic Acid/Vanadate complex bound to chymotrypsin A 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Moulin, A, Bell, J.H, Pratt, R.F, Ringe, D. 登録日 2007-03-22 公開日 2007-05-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic Acid: structure of the inert complex and its mechanistic interpretation. Biochemistry, 46, 2007
4KVP	Human p53 Core Domain Mutant V157F 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Wallentine, B.D, Wang, Y, Luecke, H. 登録日 2013-05-22 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue. Acta Crystallogr.,Sect.D, 69, 2013

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