2PCX

Crystal structure of p53DBD(R282Q) at 1.54-angstrom Resolution

Summary for 2PCX

• Entry DOI: 10.2210/pdb2pcx/pdb
• Related: 1TSR 1UOL 2AC0 2ADY 2AHI 2ATA
• Descriptor: Cellular tumor antigen p53, ZINC ION (3 entities in total)
• Functional Keywords: p53, p53 hotspots, p53 dna-binding domain, p53dbd, p53dbd(r282q), transcription
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• Total number of polymer chains: 1
• Total formula weight: 24871.61

Authors

Tu, C.,Shaw, G.,Ji, X. (deposition date: 2007-03-30, release date: 2008-04-08, Last modification date: 2023-08-30)

• Primary citation: Tu, C.,Tan, Y.H.,Shaw, G.,Zhou, Z.,Bai, Y.,Luo, R.,Ji, X.; Impact of low-frequency hotspot mutation R282Q on the structure of p53 DNA-binding domain as revealed by crystallography at 1.54 angstroms resolution.; Acta Crystallogr.,Sect.D, 64:471-477, 2008; PubMed: 18453682; DOI: 10.1107/S0907444908003338

Experimental method

X-RAY DIFFRACTION (1.54 Å)