PDB: 304 件ウェブページステータス検索Chemie searchBIRD

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1U5A	Plasmodium falciparum lactate dehydrogenase complexed with 3,5-dihydroxy-2-naphthoic acid 分子名称: 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase 著者 Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. 登録日 2004-07-27 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol.Biochem.Parasitol., 142, 2005
1U4S	Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedisulphonic acid 分子名称: L-lactate dehydrogenase, NAPHTHALENE-2,6-DISULFONIC ACID 著者 Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. 登録日 2004-07-26 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol.Biochem.Parasitol., 142, 2005
1WZE	Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus 分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. 登録日 2005-03-04 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for alteration of cofactor specificity of malate dehydrogenase from Thermus flavus to be published
1UXI	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface 分子名称: FUMARIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
1UXH	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface 分子名称: FUMARIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
1UXG	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface. 分子名称: FUMARIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
1UXJ	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface 分子名称: CADMIUM ION, CHLORIDE ION, MALATE DEHYDROGENASE, ... 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
1WZI	Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus 分子名称: Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. 登録日 2005-03-05 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for alteration of cofactor specificity of malate dehydrogenase from Thermus flavus to be published
1UXK	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface 分子名称: CADMIUM ION, CHLORIDE ION, MALATE DEHYDROGENASE, ... 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
1V6A	Crystal Structure of L-lactate dehydrogenase from Cyprinus carpio 分子名称: L-lactate dehydrogenase A chain, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose 著者 Watanabe, K, Motoshima, H. 登録日 2003-11-28 公開日 2005-02-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of L-lactate dehydrogenase from Cyprinus carpio To be Published
1T2E	Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase, ... 著者 Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. 登録日 2004-04-21 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
1T26	Plasmodium falciparum lactate dehydrogenase complexed with NADH and 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase 著者 Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. 登録日 2004-04-20 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
1U4O	Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2,6-DICARBOXYNAPHTHALENE, L-lactate dehydrogenase 著者 Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. 登録日 2004-07-26 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol.Biochem.Parasitol., 142, 2005
1U5C	Plasmodium falciparum lactate dehydrogenase complexed with 3,7-dihydroxynaphthalene-2-carboxylic acid and NAD+ 分子名称: 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. 登録日 2004-07-27 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol.Biochem.Parasitol., 142, 2005
1XIV	Plasmodium falciparum lactate dehydrogenase complexed with 2-({4-chloro-[hydroxy(methoxy)methyl]cyclohexyl}amino)ethane-1,1,2-triol 分子名称: 2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL, GLYCEROL, L-lactate dehydrogenase 著者 Conners, R, Cameron, A, Read, J.A, Schambach, F, Sessions, R.B, Brady, R.L. 登録日 2004-09-22 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase MOL.BIOCHEM.PARASITOL., 142, 2005
1UR5	Stabilization of a Tetrameric Malate Dehydrogenase by Introduction of a Disulfide Bridge at the Dimer/Dimer Interface 分子名称: CADMIUM ION, CHLORIDE ION, MALATE DEHYDROGENASE, ... 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2003-10-27 公開日 2003-11-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Stabilization of a Tetrameric Malate Dehydrogenase by Introduction of a Disulfide Bridge at the Dimer-Dimer Interface J.Mol.Biol., 334, 2003
4M49	Lactate Dehydrogenase A in complex with a substituted pyrazine inhibitor compound 18 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-(5-amino-6-{[(1R)-1-phenylethyl]amino}pyrazin-2-yl)-4-chlorobenzoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Eigenbrot, C, Ultsch, M. 登録日 2013-08-06 公開日 2013-09-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.052 Å) 主引用文献 Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 23, 2013
4ND4	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4OJN	Crystal structure of human muscle L-lactate dehydrogenase 分子名称: GLYCEROL, L-lactate dehydrogenase A chain, PENTAETHYLENE GLYCOL 著者 Kolappan, S, Craig, L. 登録日 2014-01-21 公開日 2014-12-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. Acta Crystallogr.,Sect.D, 71, 2015
4OKN	Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, KANAMYCIN A, L-lactate dehydrogenase A chain, ... 著者 Kolappan, S, Craig, L. 登録日 2014-01-22 公開日 2014-12-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms. Acta Crystallogr.,Sect.D, 71, 2015
4ND5	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum 分子名称: Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND2	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor analog (3-acetylpyridine adenine dinucleotide) 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, GLYCEROL, Lactate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND1	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with cofactor (b-nicotinamide adenine dinucleotide) and inhibitor (oxamic acid) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4PLH	Crystal structure of ancestral apicomplexan malate dehydrogenase with oxamate. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, SODIUM ION, ... 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-16 公開日 2014-07-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
4PLW	Crystal structure of ancestral apicomplexan malate dehydrogenase with lactate. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PHOSPHATE ION, malate dehydrogenase 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-19 公開日 2014-07-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014

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