PDB: 593 件ウェブページステータス検索Chemie searchBIRD

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6UUF	Crystal structure of a Nudix Hydrolase from M. Smegmatis, RenU 分子名称: Nudix Hydrolase, RenU 著者 Wright, K.M, Yoder, J, Shoemaker, S, Hernandez, A, Iheanacho, A, Marques, I, Amzel, M.L, Gabelli, S.B. 登録日 2019-10-30 公開日 2021-05-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of RenU To Be Published
5MZG	Crystal structure of mouse MTH1 in complex with TH588 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION, ... 著者 Narwal, M, Jemth, A.-S, Helleday, T, Stenmark, P. 登録日 2017-01-31 公開日 2018-01-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry, 57, 2018
5NGS	Crystal structure of human MTH1 in complex with inhibitor 6-[(2-phenylethyl)sulfanyl]-7H-purin-2-amine 分子名称: 6-(2-phenylethylsulfanyl)-7~{H}-purin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ... 著者 Gustafsson, R, Rudling, A, Almlof, I, Homan, E, Scobie, M, Warpman Berglund, U, Helleday, T, Carlsson, J, Stenmark, P. 登録日 2017-03-20 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space. J. Med. Chem., 60, 2017
5NGR	Crystal structure of human MTH1 in complex with fragment inhibitor 8-(methylsulfanyl)-7H-purin-6-amine 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-methylsulfanyl-7~{H}-purin-6-amine, SULFATE ION 著者 Gustafsson, R, Rudling, A, Almlof, I, Homan, E, Scobie, M, Warpman Berglund, U, Helleday, T, Carlsson, J, Stenmark, P. 登録日 2017-03-20 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space. J. Med. Chem., 60, 2017
1K26	Structure of a Nudix Protein from Pyrobaculum aerophilum Solved by the Single Wavelength Anomolous Scattering Method 分子名称: ACETIC ACID, GLYCEROL, IRIDIUM (III) ION, ... 著者 Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2001-09-26 公開日 2002-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr.,Sect.D, 58, 2002
6YPB	NUDIX1 hydrolase from Rosa x hybrida 分子名称: Geranyl diphosphate phosphohydrolase 著者 Degut, C, Rety, S, Tisne, C, Baudino, S. 登録日 2020-04-15 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Functional diversification in the Nudix hydrolase gene family drives sesquiterpene biosynthesis in Rosa × wichurana. Plant J., 104, 2020
3X0L	ADP ribose pyrophosphatase from Thermus thermophilus HB8 in ES-state at 1.00 angstrom resolution 分子名称: ADP-ribose pyrophosphatase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N. 登録日 2014-10-17 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Biochemistry, 55, 2016
3X0K	ADP ribose pyrophosphatase from Thermus thermophilus HB8 in ES-state at 0.97 angstrom resolution 分子名称: ADP-ribose pyrophosphatase, GLYCEROL, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N. 登録日 2014-10-16 公開日 2016-04-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Biochemistry, 55, 2016
3X0Q	ADP ribose pyrophosphatase from Thermus thermophilus HB8 in ESMM-state at reaction time of 20 min 分子名称: ADP-ribose pyrophosphatase, GLYCEROL, MANGANESE (II) ION, ... 著者 Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N. 登録日 2014-10-17 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Biochemistry, 55, 2016
3X0I	ADP ribose pyrophosphatase in apo state at 0.91 angstrom resolution 分子名称: ADP-ribose pyrophosphatase, GLYCEROL, SULFATE ION 著者 Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N. 登録日 2014-10-16 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (0.91 Å) 主引用文献 ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Biochemistry, 55, 2016
3X0N	ADP ribose pyrophosphatase from Thermus thermophilus HB8 in ESM-state at reaction time of 6 min 分子名称: ADP-ribose pyrophosphatase, GLYCEROL, MANGANESE (II) ION, ... 著者 Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N. 登録日 2014-10-17 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Biochemistry, 55, 2016
1K2E	crystal structure of a nudix protein from Pyrobaculum aerophilum 分子名称: ACETIC ACID, GLYCEROL, NICKEL (II) ION, ... 著者 Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2001-09-26 公開日 2002-04-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr.,Sect.D, 58, 2002
5MZE	Crystal structure of mouse MTH1 with 8-oxo-dGTP 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, COPPER (II) ION, ... 著者 Narwal, M, Jemth, A.-S, Helleday, T, Stenmark, P. 登録日 2017-01-31 公開日 2018-01-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry, 57, 2018
5NQR	Potent inhibitors of NUDT5 silence hormone signaling in breast cancer 分子名称: 8-(dimethylamino)-1,3-dimethyl-7-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl]purine-2,6-dione, ADP-sugar pyrophosphatase 著者 Carter, M, Stenmark, P. 登録日 2017-04-21 公開日 2018-01-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat Commun, 9, 2018
3GWY	Crystal structure of putative CTP pyrophosphohydrolase from Bacteroides fragilis 分子名称: Putative CTP pyrophosphohydrolase 著者 Patskovsky, Y, Romero, R, Gilmore, M, Do, J, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-04-01 公開日 2009-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Ctp Pyrophosphohydrolase from Bacteroides fragilis To be Published
1MR2	Structure of the MT-ADPRase in complex with 1 Mn2+ ion and AMP-CP (a inhibitor), a nudix enzyme 分子名称: ADPR pyrophosphatase, MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER 著者 Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. 登録日 2002-09-17 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
1KT9	Crystal Structure of C. elegans Ap4A Hydrolase 分子名称: Diadenosine Tetraphosphate Hydrolase 著者 Bailey, S, Sedelnikova, S.E, Blackburn, G.M, Abdelghany, H.M, Baker, P.J, McLennan, A.G, Rafferty, J.B. 登録日 2002-01-15 公開日 2002-05-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms Structure, 10, 2002
1MP2	Structure of MT-ADPRase (Apoenzyme), a Nudix hydrolase from Mycobacterium tuberculosis 分子名称: ADPR pyrophosphatase 著者 Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. 登録日 2002-09-11 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
1MQE	Structure of the MT-ADPRase in complex with gadolidium and ADP-ribose, a Nudix enzyme 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADPR pyrophosphatase, GADOLINIUM ION 著者 Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. 登録日 2002-09-16 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
1MK1	Structure of the MT-ADPRase in complex with ADPR, a Nudix enzyme 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADPR pyrophosphatase 著者 Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. 登録日 2002-08-28 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
1MQW	Structure of the MT-ADPRase in complex with three Mn2+ ions and AMPCPR, a Nudix enzyme 分子名称: ADPR pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, MANGANESE (II) ION 著者 Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. 登録日 2002-09-17 公開日 2003-08-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
3GG6	Crystal structure of the NUDIX domain of human NUDT18 分子名称: Nucleoside diphosphate-linked moiety X motif 18 著者 Tresaugues, L, Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) 登録日 2009-02-27 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the NUDIX domain of human NUDT18 To be Published
3GRN	CRYSTAL STRUCTURE OF MUTT PROTEIN FROM Methanosarcina mazei Go1 分子名称: GLYCEROL, MutT related protein 著者 Patskovsky, Y, Romero, R, Gilmore, M, Do, J, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-03-26 公開日 2009-04-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 CRYSTAL STRUCTURE OF MUTT PROTEIN FROM Methanosarcina mazei Go1 To be Published
3X0P	ADP ribose pyrophosphatase from Thermus thermophilus HB8 in ESMM-state at reaction time of 15 min 分子名称: ADP-ribose pyrophosphatase, GLYCEROL, MANGANESE (II) ION, ... 著者 Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N. 登録日 2014-10-17 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Biochemistry, 55, 2016
3X0M	ADP ribose pyrophosphatase from Thermus thermophilus HB8 in ESM-state at reaction time of 3 min 分子名称: ADP-ribose pyrophosphatase, GLYCEROL, MANGANESE (II) ION, ... 著者 Furuike, Y, Akita, Y, Miyahara, I, Kamiya, N. 登録日 2014-10-17 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors Biochemistry, 55, 2016

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