PDB: 259 件ウェブページステータス検索Chemie searchBIRD

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3UZT	Structure of the C13.18 RNA Aptamer in Complex with G Protein-Coupled Receptor Kinase 2 分子名称: Beta-adrenergic receptor kinase 1, C13.18 RNA Aptamer, MAGNESIUM ION 著者 Tesmer, J.J.G, Tesmer, V.M. 登録日 2011-12-07 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20, 2012
3V5W	Human G Protein-Coupled Receptor Kinase 2 in Complex with Soluble Gbetagamma Subunits and Paroxetine 分子名称: G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Thal, D.M, Tesmer, J.J.G. 登録日 2011-12-17 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility. Acs Chem.Biol., 7, 2012
3UZS	Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex 分子名称: Beta-adrenergic receptor kinase 1, C13.28 RNA Aptamer, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Tesmer, J.J.G, Tesmer, V.M. 登録日 2011-12-07 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.52 Å) 主引用文献 Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20, 2012
2NZ8	N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1 分子名称: ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein 著者 Chhatriwala, M.K, Betts, L, Worthylake, D.K, Sondek, J. 登録日 2006-11-22 公開日 2007-04-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation J.Mol.Biol., 368, 2007
2PZ1	Crystal Structure of Auto-inhibited Asef 分子名称: Rho guanine nucleotide exchange factor 4 著者 Betts, L, Sondek, J, Rossman, K.L. 登録日 2007-05-17 公開日 2007-08-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression. Nat.Struct.Mol.Biol., 14, 2007
3BJI	Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 分子名称: Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION 著者 Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) 登録日 2007-12-04 公開日 2008-07-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J.Mol.Biol., 380, 2008
2DX1	Crystal structure of RhoGEF protein Asef 分子名称: Rho guanine nucleotide exchange factor 4 著者 Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-08-22 公開日 2007-01-02 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism J.Biol.Chem., 282, 2007
2BCJ	Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma Subunits 分子名称: G-protein-coupled receptor kinase 2, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Tesmer, J.J.G. 登録日 2005-10-19 公開日 2005-12-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.061 Å) 主引用文献 Snapshot of Activated G Proteins at the Membrane: The Gq-GRK2-G Complex Science, 310, 2005
2DFK	Crystal structure of the CDC42-Collybistin II complex 分子名称: GLYCEROL, SULFATE ION, cell division cycle 42 isoform 1, ... 著者 Xiang, S, Kim, E.Y, Connelly, J.J, Nassar, N, Kirsch, J, Winking, J, Schwarz, G, Schindelin, H. 登録日 2006-03-02 公開日 2006-05-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor. J.Mol.Biol., 359, 2006

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