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2P2L
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Rac1-GDP-Zinc Complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ZINC ION
著者Prehna, G, Stebbins, C.E.
登録日2007-03-07
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium.
Acta Crystallogr.,Sect.D, 63, 2007
2EQB
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BU of 2eqb by Molmil
Crystal structure of the Rab GTPase Sec4p, the Sec2p GEF domain, and phosphate complex
分子名称: PHOSPHATE ION, Rab guanine nucleotide exchange factor SEC2, Ras-related protein SEC4
著者Sato, Y, Fukai, S, Ishitani, R, Nureki, O.
登録日2007-03-30
公開日2007-05-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the Sec4p{middle dot}Sec2p complex in the nucleotide exchanging intermediate state
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q3H
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The crystal structure of RhouA in the GDP-bound state.
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras homolog gene family, ...
著者Gileadi, C, Yang, X, Papagrigoriou, E, Elkins, J, Zhao, Y, Bray, J, Gileadi, O, Umeano, C, Ugochukwu, E, Uppenberg, J, Bunkoczi, G, von Delft, F, Pike, A.C.W, Phillips, C, Savitsky, P, Fedorov, O, Edwards, A, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-05-30
公開日2007-06-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The crystal structure of RhouA in the GDP-bound state.
To be Published
2UZI
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BU of 2uzi by Molmil
Crystal structure of HRAS(G12V) - anti-RAS Fv complex
分子名称: ANTI-RAS FV HEAVY CHAIN, ANTI-RAS FV LIGHT CHAIN, GTPASE HRAS, ...
著者Tanaka, T, williams, R.L, Rabbitts, T.H.
登録日2007-04-27
公開日2007-06-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tumour Prevention by a Single Antibody Domain Targeting the Interaction of Signal Transduction Proteins with Ras.
Embo J., 26, 2007
2HXS
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Crystal Structure of Rab28A GTPase in the Inactive (GDP-3'P-Bound) Form
分子名称: GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-28
著者Lee, S.H, Li, Y, Dominguez, R.
登録日2006-08-03
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The Crystal Structure of Rab28 GTPase in Active and Inactive Forms
To be Published
2QME
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Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1)
分子名称: CRIB domain of the Serine/threonine-protein kinase PAK 1, GLYCEROL, MAGNESIUM ION, ...
著者Ugochukwu, E, Yang, X, Elkins, J.M, Burgess-Brown, N, Bunkoczi, G, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC)
登録日2007-07-16
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 1 (PAK1).
To be Published
2RMK
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Rac1/PRK1 Complex
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1, ...
著者Modha, R, Campbell, L.J, Nietlispach, D, Buhecha, H.R, Owen, D, Mott, H.R.
登録日2007-10-25
公開日2007-11-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The Rac1 Polybasic Region Is Required for Interaction with Its Effector PRK1
J.Biol.Chem., 283, 2008
2REX
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Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase
分子名称: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Tong, Y, Tempel, W, Shen, L, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-09-27
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
To be Published
3BFK
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BU of 3bfk by Molmil
Crystal structure of Plasmodium falciparum Rab11a in complex with GDP
分子名称: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Small GTPase Rab11
著者Pizarro, J.C, Sukumar, D, Hassanali, A, Lin, L, Wernimont, A.K, Lew, J, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
登録日2007-11-21
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Plasmodium falciparum Rab11a in complex with GDP.
To be Published
2QUZ
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Crystal Structure of the activating H-RasK117R mutant in Costello Syndrome, bound to Mg-GDP
分子名称: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Parret, A, Scheffzek, K.
登録日2007-08-07
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation.
Hum.Mutat., 29, 2008
2RGE
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Crystal structure of H-Ras-GppNHp
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Buhrman, G, Wink, G, Mattos, C.
登録日2007-10-03
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
Structure, 15, 2007
2RGB
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BU of 2rgb by Molmil
Crystal structure of H-RasQ61K-GppNHp
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Buhrman, G, Wink, G, Mattos, C.
登録日2007-10-03
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
Structure, 15, 2007
2RGG
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Crystal structure of H-RasQ61I-GppNHp, trigonal crystal form
分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Buhrman, G, Wink, G, Mattos, C.
登録日2007-10-03
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
Structure, 15, 2007
2RGA
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Crystal structure of H-RasQ61I-GppNHp
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Buhrman, G, Wink, G, Mattos, C.
登録日2007-10-03
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
Structure, 15, 2007
2RGC
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Crystal structure of H-RasQ61V-GppNHp
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Buhrman, G, Wink, G, Mattos, C.
登録日2007-10-03
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
Structure, 15, 2007
2RGD
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Crystal structure of H-RasQ61L-GppNHp
分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ...
著者Buhrman, G, Wink, G, Mattos, C.
登録日2007-10-03
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf.
Structure, 15, 2007
2RGN
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Crystal Structure of p63RhoGEF complex with Galpha-q and RhoA
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(q) subunit alpha, MAGNESIUM ION, ...
著者Shankaranarayanan, A, Nance, M.R, Tesmer, J.J.G.
登録日2007-10-04
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs.
Science, 318, 2007
2VH5
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CRYSTAL STRUCTURE OF HRAS(G12V) - ANTI-RAS FV (disulfide free mutant) COMPLEX
分子名称: ANTI-RAS FV HEAVY CHAIN, ANTI-RAS FV LIGHT CHAIN, GTPASE HRAS, ...
著者Tanaka, T, Williams, R.L, Rabbitts, T.H.
登録日2007-11-19
公開日2008-01-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Functional Intracellular Antibody Fragments Do not Require Invariant Intra-Domain Disulfide Bonds.
J.Mol.Biol., 376, 2008
2E9S
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human neuronal Rab6B in three intermediate forms
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NITRATE ION, ...
著者Vellieux, F.M, Tcherniuk, S, Garcia-Saez, I, Kozielski, F.
登録日2007-01-26
公開日2008-01-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献3D structure of human neuronal Rab6B in three intermediate forms
To be Published
3BBP
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Rab6-GTP:GCC185 Rab binding domain complex
分子名称: GRIP and coiled-coil domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Schweizer Burguete, A, Fenn, T.D, Brunger, A.T, Pfeffer, S.R.
登録日2007-11-09
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.
Cell(Cambridge,Mass.), 132, 2008
3C5C
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Crystal structure of human Ras-like, family 12 protein in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-like protein 12, ...
著者Shen, L, Tong, Y, Tempel, W, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of human Ras-like, family 12 protein in complex with GDP.
To be Published
3C5H
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Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP)
分子名称: Glucocorticoid receptor DNA-binding factor 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Ras homolog domain of human GRLF1 (p190RhoGAP).
To be Published
2EFC
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Ara7-GDP/AtVps9a
分子名称: GUANOSINE-5'-DIPHOSPHATE, Similarity to vacuolar protein sorting-associated protein VPS9, Small GTP-binding protein-like
著者Uejima, T, Ihara, K, Goh, T, Ito, E, Sunada, M, Ueda, T, Nakano, A, Wakatsuki, S.
登録日2007-02-22
公開日2008-02-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献GDP-bound and nucleotide-free intermediates of the guanine nucleotide exchange in the Rab5/Vps9 system
J.Biol.Chem., 285, 2010
2EFD
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Ara7/AtVps9a
分子名称: Similarity to vacuolar protein sorting-associated protein VPS9, Small GTP-binding protein-like
著者Uejima, T, Ihara, K, Wakatsuki, S.
登録日2007-02-22
公開日2008-02-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献GDP-bound and nucleotide-free intermediates of the guanine nucleotide exchange in the Rab5/Vps9 system
J.Biol.Chem., 285, 2010
2EFE
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Ara7-GDPNH2/AtVps9a
分子名称: AMINOPHOSPHONIC ACID-GUANYLATE ESTER, Similarity to vacuolar protein sorting-associated protein VPS9, Small GTP-binding protein-like
著者Ihara, K, Uejima, T, Wakatsuki, S.
登録日2007-02-22
公開日2008-02-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献GDP-bound and nucleotide-free intermediates of the guanine nucleotide exchange in the Rab5/Vps9 system
J.Biol.Chem., 285, 2010

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