PDB: 1628 件ウェブページステータス検索Chemie searchBIRD

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5UG3	NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID MUTANT A10V 分子名称: Alpha-conotoxin GID 著者 Hussein, A.K, Leffler, A.E, Zebroski, H.A, Powell, S.R, Kuryatov, A, Filipenko, P, Gorson, J, Heizmann, A, Lyskov, S, Nicke, A, Lindstrom, J, Rudy, B, Bonneau, R, Holford, M, Poget, S.F. 登録日 2017-01-06 公開日 2017-09-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UG5	NMR SOLUTION STRUCTURE OF THE ALPHA-CONOTOXIN GID MUTANT V13Y 分子名称: Alpha-conotoxin GID 著者 Hussein, A, Leffler, A.E, Kuryatov, A, Zebroski, H.A, Powell, S.R, Filipenko, P, Gorson, J, Heizmann, A, Lyskov, S, Nicke, A, Lindstrom, J, Rudy, B, Bonneau, R, Holford, M, Poget, S.F. 登録日 2017-01-06 公開日 2017-09-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2FRB	NMR structure of the alpha-conotoxin GI (ASN4)-benzoylphenylalanine derivative 分子名称: Alpha-conotoxin GIA 著者 Pashkov, V.S, Maslennikov, I, Kasheverov, I.V, Zhmak, M.N, Utkin, Y.N, Tsetlin, V.I, Arseniev, A.S. 登録日 2006-01-19 公開日 2006-05-30 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor. Febs J., 273, 2006
2FR9	NMR structure of the alpha-conotoxin GI (SER12)-benzoylphenylalanine derivative 分子名称: Alpha-conotoxin GI 著者 Pashkov, V.S, Maslennikov, I.V, Kasheverov, I.E, Zhmak, M.N, Utkin, Y.N, Tsetlin, V.I, Arseniev, A.S. 登録日 2006-01-19 公開日 2006-05-30 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor. Febs J., 273, 2006
3SH1	Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nemecz, A, Taylor, P.W. 登録日 2011-06-15 公開日 2011-10-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Creating an alpha-7 nicotinic acetylcholine recognition domain from the acetylcholine binding protein: crystallographic and ligand selectivity analyses J.Biol.Chem., 286, 2011
3SIO	Ac-AChBP ligand binding domain (not including beta 9-10 linker) mutated to human alpha-7 nAChR 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nemecz, A, Taylor, P.W. 登録日 2011-06-19 公開日 2011-10-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Creating an alpha-7 nicotinic acetylcholine recognition domain from the acetylcholine binding protein: crystallographic and ligand selectivity analyses J.Biol.Chem., 286, 2011
3T4M	Ac-AChBP ligand binding domain mutated to human alpha-7 nAChR (intermediate) 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nemecz, A, Taylor, P.W. 登録日 2011-07-26 公開日 2011-10-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Creating an alpha-7 nicotinic acetylcholine recognition domain from the acetylcholine binding protein: crystallographic and ligand selectivity analyses J.Biol.Chem., 286, 2011
5FJV	Crystal structure of the extracellular domain of alpha2 nicotinic acetylcholine receptor in pentameric assembly 分子名称: EPIBATIDINE, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 著者 Giastas, P, Kouvatsos, N, Chroni-Tzartou, D, Tzartos, S.J. 登録日 2015-10-13 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal Structure of a Human Neuronal Nachr Extracellular Domain in Pentameric Assembly: Ligand-Bound Alpah2 Homopentamer. Proc.Natl.Acad.Sci.USA, 113, 2016
3LII	Recombinant human acetylcholinesterase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, SULFATE ION 著者 Dvir, H, Rosenberry, T, Harel, M, Silman, I, Sussman, J. 登録日 2010-01-25 公開日 2010-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Acetylcholinesterase: From 3D structure to function. Chem.Biol.Interact, 187, 2010
3WTL	Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Nitromethylene Analogue of Imidacloprid 分子名称: 2-chloro-5-{[(2E)-2-(nitromethylidene)imidazolidin-1-yl]methyl}pyridine, Acetylcholine-binding protein 著者 Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. 登録日 2014-04-11 公開日 2015-02-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
3WTM	Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Nitromethylene Analogue of Imidacloprid 分子名称: 2-chloro-5-{[(2E)-2-(nitromethylidene)imidazolidin-1-yl]methyl}pyridine, Acetylcholine-binding protein 著者 Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. 登録日 2014-04-11 公開日 2015-02-04 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
3WTO	Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Desnitro-imidacloprid 分子名称: (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine, Acetylcholine-binding protein 著者 Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. 登録日 2014-04-11 公開日 2015-02-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
3WTI	Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Clothianidin 分子名称: 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine, Acetylcholine-binding protein 著者 Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. 登録日 2014-04-11 公開日 2015-02-04 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
3WTH	Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Imidacloprid 分子名称: (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine, Acetylcholine-binding protein 著者 Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. 登録日 2014-04-11 公開日 2015-02-04 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
3WTN	Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Desnitro-imidacloprid 分子名称: (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine, Acetylcholine-binding protein, CADMIUM ION, ... 著者 Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. 登録日 2014-04-11 公開日 2015-02-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
8FX5	Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline 分子名称: Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Vuckovic, Z, Mobbs, J.I, Glukhova, A, Sexton, P.M, Danev, R, Thal, D.M. 登録日 2023-01-23 公開日 2023-09-13 実験手法 ELECTRON MICROSCOPY (2.45 Å) 主引用文献 Xanomeline displays concomitant orthosteric and allosteric binding modes at the M 4 mAChR. Nat Commun, 14, 2023
1UL2	Solution Conformation of alpha-Conotoxin GIC 分子名称: alpha-conotoxin GIC 著者 Chi, S.-W, Kim, D.-H, Olivera, B.M, McIntosh, J.M, Han, K.-H. 登録日 2003-09-06 公開日 2004-07-20 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors Biochem.J., 380, 2004
7LD3	Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist and an allosteric ligand 分子名称: ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Draper-Joyce, C.J, Danev, R, Thal, D.M, Christopoulos, A, Glukhova, A. 登録日 2021-01-12 公開日 2021-09-08 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Positive allosteric mechanisms of adenosine A 1 receptor-mediated analgesia. Nature, 597, 2021
7LD4	Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist 分子名称: ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Draper-Joyce, C.J, Danev, R, Thal, D.M, Christopoulos, A, Glukhova, A. 登録日 2021-01-12 公開日 2021-09-08 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Positive allosteric mechanisms of adenosine A 1 receptor-mediated analgesia. Nature, 597, 2021
1K64	NMR Structue of alpha-conotoxin EI 分子名称: alpha-conotoxin EI 著者 Park, K.H, Suk, J.E, Jacobsen, R, Gray, W.R, McIntosh, J.M, Han, K.H. 登録日 2001-10-15 公開日 2003-09-09 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor J.BIOL.CHEM., 276, 2001
2GCZ	Solution Structure of alpha-Conotoxin OmIA 分子名称: Alpha-conotoxin OmIA 著者 Chi, S.-W, Kim, D.-H, Olivera, B.M, McIntosh, J.M, Han, K.-H. 登録日 2006-03-15 公開日 2006-07-25 最終更新日 2020-06-24 実験手法 SOLUTION NMR 主引用文献 Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes Biochem.Biophys.Res.Commun., 345, 2006
1ZLC	Solution Conformation of alpha-conotoxin PIA 分子名称: Alpha-conotoxin PIA 著者 Chi, S.-W, Lee, S.-H, Kim, D.-H, Kim, J.-S, Olivera, B.M, McIntosh, J.M, Han, K.-H. 登録日 2005-05-05 公開日 2006-05-02 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors Biochem.Biophys.Res.Commun., 338, 2005
2L03	Spatial structure of water-soluble Lynx1 分子名称: Ly-6/neurotoxin-like protein 1 著者 Mineev, K.S, Shenkarev, Z.O, Arseniev, A.S. 登録日 2010-06-30 公開日 2011-01-19 最終更新日 2014-10-01 実験手法 SOLUTION NMR 主引用文献 NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1 J.Biol.Chem., 286, 2011
1RGJ	NMR STRUCTURE OF THE COMPLEX BETWEEN ALPHA-BUNGAROTOXIN AND MIMOTOPE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR WITH ENHANCED ACTIVITY 分子名称: MIMOTOPE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR, long neurotoxin 1 著者 Bernini, A, Spiga, O, Ciutti, A, Scarselli, M, Bracci, L, Lozzi, L, Lelli, B, Neri, P, Niccolai, N. 登録日 2003-11-12 公開日 2003-11-25 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 NMR and MD studies on the interaction between ligand peptides and alpha-bungarotoxin. J.Mol.Biol., 339, 2004
2HA4	Crystal structure of mutant S203A of mouse acetylcholinesterase complexed with acetylcholine 分子名称: ACETATE ION, ACETYLCHOLINE, Acetylcholinesterase, ... 著者 Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P. 登録日 2006-06-12 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding J.Biol.Chem., 281, 2006

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