3WTH

Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Imidacloprid

Summary for 3WTH

Entry DOI	10.2210/pdb3wth/pdb
Related	2ZJU 2ZJV
Descriptor	Acetylcholine-binding protein, (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine (3 entities in total)
Functional Keywords	neonicotinoids, nicotinic acetylcholine receptor, imidacloprid, acetylcholine binding, signaling protein
Biological source	Lymnaea stagnalis (Great pond snail)
Cellular location	Secreted: P58154
Total number of polymer chains	5
Total formula weight	122532.68
Authors	Okajima, T.,Ihara, M.,Yamashita, A.,Oda, T.,Matsuda, K. (deposition date: 2014-04-11, release date: 2015-02-04)
Primary citation	Ihara, M.,Okajima, T.,Yamashita, A.,Oda, T.,Asano, T.,Matsui, M.,Sattelle, D.B.,Matsuda, K. Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86:736-746, 2014 Cited by PubMed: 25267717 DOI: 10.1124/mol.114.094698 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.54 Å)

Structure validation