6KK4
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![BU of 6kk4 by Molmil](/molmil-images/mine/6kk4) | Crystal structure of Zika NS2B-NS3 protease with compound 9 | 分子名称: | 1-[(9~{R},16~{S},19~{S})-16,19-bis(4-azanylbutyl)-4,8,15,18,21-pentakis(oxidanylidene)-3,7,14,17,20-pentazabicyclo[21.3.1]heptacosa-1(26),23(27),24-trien-9-yl]guanidine, GLYCEROL, NS3 protease, ... | 著者 | Quek, J.P. | 登録日 | 2019-07-23 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses. Chemmedchem, 15, 2020
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6KK2
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![BU of 6kk2 by Molmil](/molmil-images/mine/6kk2) | Crystal structure of Zika NS2B-NS3 protease with compound 2 | 分子名称: | 1-[(10~{S},17~{S},20~{S})-17,20-bis(4-azanylbutyl)-4,9,16,19,22-pentakis(oxidanylidene)-3,8,15,18,21-pentazabicyclo[22.2.2]octacosa-1(27),24(28),25-trien-10-yl]guanidine, NS3 protease, Serine protease subunit NS2B | 著者 | Quek, J.P. | 登録日 | 2019-07-23 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses. Chemmedchem, 15, 2020
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6KPQ
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![BU of 6kpq by Molmil](/molmil-images/mine/6kpq) | Crystal structure of Zika NS2B-NS3 protease with compound 8 | 分子名称: | 1-[(10~{R},17~{S},20~{S})-17,20-bis(4-azanylbutyl)-4,9,16,19,22-pentakis(oxidanylidene)-3,8,15,18,21-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-trien-10-yl]guanidine, NS3 protease, Serine protease subunit NS2B | 著者 | Quek, J.P. | 登録日 | 2019-08-15 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses. Chemmedchem, 15, 2020
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7BPK
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![BU of 7bpk by Molmil](/molmil-images/mine/7bpk) | Zika virus envelope protein mutant bound to mAb | 分子名称: | Envelope protein, IG c307_light_IGLV1-51_IGLJ2, Z3L1 Heavy chain | 著者 | Dai, L, Qi, J, Gao, G.F. | 登録日 | 2020-03-23 | 公開日 | 2021-03-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021
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7BQ5
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![BU of 7bq5 by Molmil](/molmil-images/mine/7bq5) | ZIKV sE bound to mAb Z6 | 分子名称: | Z6 Light Chain, Z6 heavy chain, envelope protein | 著者 | Dai, L, Qi, J, Gao, G.F. | 登録日 | 2020-03-24 | 公開日 | 2021-03-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch. Nat.Immunol., 22, 2021
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8JN5
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![BU of 8jn5 by Molmil](/molmil-images/mine/8jn5) | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 37 deg C (subparticle LLR-LRR) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | 登録日 | 2023-06-06 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
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8JN4
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![BU of 8jn4 by Molmil](/molmil-images/mine/8jn4) | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 4 deg C (subparticle LLR-LRR) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | 登録日 | 2023-06-06 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
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8JN6
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![BU of 8jn6 by Molmil](/molmil-images/mine/8jn6) | Cryo-EM structure of the small tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | 分子名称: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | 登録日 | 2023-06-06 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
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8JN1
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![BU of 8jn1 by Molmil](/molmil-images/mine/8jn1) | Cryo-EM structure of dengue virus serotype 3 strain EHIE46200Y19 in complex with human antibody DENV-115 IgG at 4 deg C (subparticle LLR-LRR) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein (Fragment), Human antibody DENV-115 heavy chain, ... | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | 登録日 | 2023-06-06 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
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8JN2
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![BU of 8jn2 by Molmil](/molmil-images/mine/8jn2) | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 4 deg C (subparticle LLR-LRR) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-115 heavy chain, ... | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | 登録日 | 2023-06-06 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
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8JN3
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![BU of 8jn3 by Molmil](/molmil-images/mine/8jn3) | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 37 deg C (subparticle LLR-LRR) | 分子名称: | Envelope protein, Human antibody DENV-115 heavy chain, Human antibody DENV-115 light chain, ... | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | 登録日 | 2023-06-06 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
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8WBD
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![BU of 8wbd by Molmil](/molmil-images/mine/8wbd) | |
8WBE
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![BU of 8wbe by Molmil](/molmil-images/mine/8wbe) | |
8WBC
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![BU of 8wbc by Molmil](/molmil-images/mine/8wbc) | |
8WBB
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![BU of 8wbb by Molmil](/molmil-images/mine/8wbb) | |
4FFY
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![BU of 4ffy by Molmil](/molmil-images/mine/4ffy) | Crystal structure of DENV1-E111 single chain variable fragment bound to DENV-1 DIII, strain 16007. | 分子名称: | CHLORIDE ION, DENV1-E111 single chain variable fragment (heavy chain), DENV1-E111 single chain variable fragment (light chain), ... | 著者 | Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-06-01 | 公開日 | 2012-06-20 | 最終更新日 | 2012-10-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope. Plos Pathog., 8, 2012
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4LCY
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![BU of 4lcy by Molmil](/molmil-images/mine/4lcy) | |
6WER
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![BU of 6wer by Molmil](/molmil-images/mine/6wer) | |
6WEQ
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![BU of 6weq by Molmil](/molmil-images/mine/6weq) | DENV1 NS1 in complex with neutralizing 2B7 Fab fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab fragment heavy chain, 2B7 Fab fragment light chain, ... | 著者 | Akey, D.L, Smith, J.L. | 登録日 | 2020-04-02 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction. Science, 371, 2021
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4R05
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![BU of 4r05 by Molmil](/molmil-images/mine/4r05) | Crystal structure of the refolded DENV3 methyltransferase | 分子名称: | Nonstructural protein NS5 | 著者 | Brecher, M.B, Li, Z, Zhang, J, Chen, H, Lin, Q, Liu, B, Li, H.M. | 登録日 | 2014-07-29 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase. Protein Sci., 24, 2015
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7BSC
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![BU of 7bsc by Molmil](/molmil-images/mine/7bsc) | |
7K93
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![BU of 7k93 by Molmil](/molmil-images/mine/7k93) | |
8T12
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![BU of 8t12 by Molmil](/molmil-images/mine/8t12) | |
8T13
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![BU of 8t13 by Molmil](/molmil-images/mine/8t13) | |
8JN7
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![BU of 8jn7 by Molmil](/molmil-images/mine/8jn7) | Cryo-EM structure of the big tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | 分子名称: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | 登録日 | 2023-06-06 | 公開日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants To Be Published
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