6KK4
 
 | | Crystal structure of Zika NS2B-NS3 protease with compound 9 | | 分子名称: | 1-[(9~{R},16~{S},19~{S})-16,19-bis(4-azanylbutyl)-4,8,15,18,21-pentakis(oxidanylidene)-3,7,14,17,20-pentazabicyclo[21.3.1]heptacosa-1(26),23(27),24-trien-9-yl]guanidine, GLYCEROL, NS3 protease, ... | | 著者 | Quek, J.P. | | 登録日 | 2019-07-23 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses.
Chemmedchem, 15, 2020
|
|
6KK2
 | | Crystal structure of Zika NS2B-NS3 protease with compound 2 | | 分子名称: | 1-[(10~{S},17~{S},20~{S})-17,20-bis(4-azanylbutyl)-4,9,16,19,22-pentakis(oxidanylidene)-3,8,15,18,21-pentazabicyclo[22.2.2]octacosa-1(27),24(28),25-trien-10-yl]guanidine, NS3 protease, Serine protease subunit NS2B | | 著者 | Quek, J.P. | | 登録日 | 2019-07-23 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses.
Chemmedchem, 15, 2020
|
|
6KPQ
 | | Crystal structure of Zika NS2B-NS3 protease with compound 8 | | 分子名称: | 1-[(10~{R},17~{S},20~{S})-17,20-bis(4-azanylbutyl)-4,9,16,19,22-pentakis(oxidanylidene)-3,8,15,18,21-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-trien-10-yl]guanidine, NS3 protease, Serine protease subunit NS2B | | 著者 | Quek, J.P. | | 登録日 | 2019-08-15 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses.
Chemmedchem, 15, 2020
|
|
7BPK
 | | Zika virus envelope protein mutant bound to mAb | | 分子名称: | Envelope protein, IG c307_light_IGLV1-51_IGLJ2, Z3L1 Heavy chain | | 著者 | Dai, L, Qi, J, Gao, G.F. | | 登録日 | 2020-03-23 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch.
Nat.Immunol., 22, 2021
|
|
7BQ5
 | | ZIKV sE bound to mAb Z6 | | 分子名称: | Z6 Light Chain, Z6 heavy chain, envelope protein | | 著者 | Dai, L, Qi, J, Gao, G.F. | | 登録日 | 2020-03-24 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch.
Nat.Immunol., 22, 2021
|
|
8JN5
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 37 deg C (subparticle LLR-LRR) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
|
|
8JN4
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-290 Fab at 4 deg C (subparticle LLR-LRR) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-290 heavy chain, ... | | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
|
|
8JN6
 | | Cryo-EM structure of the small tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | | 分子名称: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
|
|
8JN1
 | | Cryo-EM structure of dengue virus serotype 3 strain EHIE46200Y19 in complex with human antibody DENV-115 IgG at 4 deg C (subparticle LLR-LRR) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein (Fragment), Human antibody DENV-115 heavy chain, ... | | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
|
|
8JN2
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 4 deg C (subparticle LLR-LRR) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein, Human antibody DENV-115 heavy chain, ... | | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
|
|
8JN3
 | | Cryo-EM structure of dengue virus serotype 3 strain 863DK in complex with human antibody DENV-115 Fab at 37 deg C (subparticle LLR-LRR) | | 分子名称: | Envelope protein, Human antibody DENV-115 heavy chain, Human antibody DENV-115 light chain, ... | | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
|
|
8WBD
 | |
8WBE
 | |
8WBC
 | |
8WBB
 | |
4FFY
 | | Crystal structure of DENV1-E111 single chain variable fragment bound to DENV-1 DIII, strain 16007. | | 分子名称: | CHLORIDE ION, DENV1-E111 single chain variable fragment (heavy chain), DENV1-E111 single chain variable fragment (light chain), ... | | 著者 | Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-06-01 | | 公開日 | 2012-06-20 | | 最終更新日 | 2012-10-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.
Plos Pathog., 8, 2012
|
|
4LCY
 | |
6WER
 | |
6WEQ
 | | DENV1 NS1 in complex with neutralizing 2B7 Fab fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab fragment heavy chain, 2B7 Fab fragment light chain, ... | | 著者 | Akey, D.L, Smith, J.L. | | 登録日 | 2020-04-02 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Science, 371, 2021
|
|
4R05
 | | Crystal structure of the refolded DENV3 methyltransferase | | 分子名称: | Nonstructural protein NS5 | | 著者 | Brecher, M.B, Li, Z, Zhang, J, Chen, H, Lin, Q, Liu, B, Li, H.M. | | 登録日 | 2014-07-29 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.
Protein Sci., 24, 2015
|
|
7BSC
 | |
7K93
 | |
8T12
 | |
8T13
 | |
8JN7
 | | Cryo-EM structure of the big tail club shape particle of dengue virus serotype 3 strain CH53489 in complex with human antibody DENV-290 Fab at 37 deg C | | 分子名称: | Human antibody DENV-290 heavy chain, Human antibody DENV-290 light chain, Polyprotein (Fragment) | | 著者 | Fibriansah, G, Ng, T.S, Tan, A.W.K, Shi, J, Lok, S.M. | | 登録日 | 2023-06-06 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (11 Å) | | 主引用文献 | Ultrapotent human antibodies lock E protein dimers of diverse DENV3 morphological variants
To Be Published
|
|
