PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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7JQ3	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI6 分子名称: 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Yang, K, Liu, W. 登録日 2020-08-10 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*. Chemmedchem, 16, 2021
2YLW	SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: Arg337Lys MUTANT IN COMPLEX WITH MES 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Orru, R, Dudek, H.M, Martinoli, C, Torres Pazmino, D.E, Royant, A, Weik, M, Fraaije, M.W, Mattevi, A. 登録日 2011-06-06 公開日 2011-06-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization. J.Biol.Chem., 286, 2011
5FSR	Crystal structure of penicillin binding protein 6B from Escherichia coli 分子名称: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACD 著者 Peters, K, Kannan, S, Rao, V.A, Bilboy, J, Vollmer, D, Erickson, S.W, Lewis, R.J, Young, K.D, Vollmer, W. 登録日 2016-01-07 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Redundancy of Peptidoglycan Carboxypeptidases Ensures Robust Cell Shape Maintenance in Escherichia Coli Mbio, 7, 2016
7JR3	SARS-CoV-2 3CL protease crystallized under reducing conditions 分子名称: 3C-like proteinase 著者 de Oliveira, R.R, Nascimento, A.F.Z, Zeri, A.C.M, Trivella, D.B.B. 登録日 2020-08-11 公開日 2020-08-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 SARS-CoV-2 3CL protease crystallized under reducing conditions. To be Published
5FMV	Crystal structure of human CD45 extracellular region, domains d1-d4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, SULFATE ION 著者 Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. 登録日 2015-11-09 公開日 2016-03-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'. Nat.Immunol., 17, 2016
5AEK	Crystal structure of the human SENP2 C548S in complex with the human SUMO1 K48M F66W 分子名称: SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 1 著者 Gallego, P, Grana-Montes, R, Espargaro, A, Castillo, V, Torrent, J, Lange, R, Papaleo, E, Lindorff-Larsend, K, Ventura, S, Reverter, D. 登録日 2014-12-23 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Stepping Back and Forward on Sumo Folding Evolution To be Published
2YO3	Salmonella enterica SadA 1185-1386 fused to GCN4 adaptors (SadAK14) 分子名称: CHLORIDE ION, GENERAL CONTROL PROTEIN GCN4, PUTATIVE INNER MEMBRANE PROTEIN 著者 Hartmann, M.D, Hernandez Alvarez, B, Lupas, A.N. 登録日 2012-10-20 公開日 2012-12-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Complete Fiber Structures of Complex Trimeric Autotransporter Adhesins Conserved in Enterobacteria. Proc.Natl.Acad.Sci.USA, 109, 2012
2UVW	Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*A)-3', 5'-D(*TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP *CP*TP*TP*CP*CP*CP*CP*C)-3', ... 著者 Irimia, A, Egli, M. 登録日 2007-03-14 公開日 2007-05-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Hydrogen Bonding of 7,8-Dihydro-8-Oxodeoxyguanosine with a Charged Residue in the Little Finger Domain Determines Miscoding Events in Sulfolobus Solfataricus DNA Polymerase Dpo4. J.Biol.Chem., 282, 2007
7JSE	Adeno-Associated Virus Origin Binding Domain in complex with ssDNA 分子名称: DNA (5'-D(*TP*TP*TP*T)-3'), Protein Rep68 著者 Escalante, C.R. 登録日 2020-08-14 公開日 2020-12-09 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states. Nucleic Acids Res., 48, 2020
7QXR	Azacoelenterazine-bound Renilla-type luciferase (AncFT) 分子名称: 3-(4-hydroxyphenyl)-8-[(4-hydroxyphenyl)methyl]-5-(phenylmethyl)-1$l^{4},4,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, Fragment transplantation onto a hyperstable ancestor of haloalkane dehalogenases and Renilla luciferase (Anc-FT) 著者 Marek, M, Schenkmayerova, A, Janin, Y.L. 登録日 2022-01-27 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.052 Å) 主引用文献 Catalytic mechanism for Renilla-type luciferases Nat Catal, 2023
7QXQ	Coelenteramide-bound Renilla-type luciferase (AncFT) 分子名称: Fragment transplantation onto hyperstable ancestor of haloalkane dehalogenases and Renilla luciferase (Anc-FT), N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE 著者 Marek, M, Schenkmayerova, A. 登録日 2022-01-27 公開日 2022-12-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.251 Å) 主引用文献 Catalytic mechanism for Renilla-type luciferases Nat Catal, 2023
2BR2	RNase PH core of the archaeal exosome 分子名称: CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2 著者 lorentzen, E, Fribourg, S, Conti, E. 登録日 2005-04-30 公開日 2005-06-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits. Nat.Struct.Mol.Biol., 12, 2005
5AFY	Thrombin in complex with 3-chloro-benzamide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-CHLORO-BENZAMIDE, DIMETHYL SULFOXIDE, ... 著者 Ruehmann, E, Heine, A, Klebe, G. 登録日 2015-01-27 公開日 2015-08-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Fragments Can Bind Either More Enthalpy or Entropy-Driven: Crystal Structures and Residual Hydration Pattern Suggest Why. J.Med.Chem., 58, 2015
7QB2	Pim1 in complex with (E)-4-((6-amino-1-methyl-2-oxoindolin-3-ylidene)methyl)benzoic acid and Pimtide 分子名称: 4-[(E)-(6-azanyl-1-methyl-2-oxidanylidene-indol-3-ylidene)methyl]benzoic acid, GLYCEROL, Pimtide, ... 著者 Hochban, P.M.M, Heine, A, Diederich, W.E. 登録日 2021-11-18 公開日 2022-11-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Pose, duplicate, then elaborate: Steps towards increased affinity for inhibitors targeting the specificity surface of the Pim-1 kinase. Eur.J.Med.Chem., 245, 2023
2X4N	Crystal structure of MHC CLass I HLA-A2.1 bound to residual fragments of a photocleavable peptide that is cleaved upon UV-light treatment 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ... 著者 Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M. 登録日 2010-02-02 公開日 2010-03-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals. J.Am.Chem.Soc., 131, 2009
1PDI	Fitting of the C-terminal part of the short tail fibers into the cryo-EM reconstruction of T4 baseplate 分子名称: Short tail fiber protein 著者 Kostyuchenko, V.A, Leiman, P.G, Chipman, P.R, Kanamaru, S, van Raaij, M.J, Arisaka, F, Mesyanzhinov, V.V, Rossmann, M.G. 登録日 2003-05-19 公開日 2003-09-09 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (12 Å) 主引用文献 Three-dimensional structure of bacteriophage T4 baseplate Nat.Struct.Biol., 10, 2003
2YQ8	Crystal structure of the SeMet-labeled N-terminal domain and peptide substrate binding domain of alpha subunit of prolyl-4 hydroxylase type I from human. 分子名称: PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 著者 Anantharajan, J, Koski, M.K, Wierenga, R.K. 登録日 2012-11-06 公開日 2013-10-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.987 Å) 主引用文献 The Structural Motifs for Substrate Binding and Dimerization of the Alpha Subunit of Collagen Prolyl 4-Hydroxylase Structure, 21, 2013
4N2S	Crystal Structure of THA8 in complex with Zm1a-6 RNA 分子名称: THA8 RNA binding protein, Zm1a-6 RNA 著者 Ke, J, Chen, R.Z, Ban, T, Zhou, X.E, Gu, X, Brunzelle, J.S, Zhu, J.K, Melcher, K, Xu, H.E. 登録日 2013-10-06 公開日 2013-10-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for RNA recognition by a dimeric PPR-protein complex. Nat.Struct.Mol.Biol., 20, 2013
4GF7	Crystal structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO), unliganded form 分子名称: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Sawa, Y, Yagi, T. 登録日 2012-08-03 公開日 2013-08-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.581 Å) 主引用文献 Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase To be Published
8W7F	Structure of Drosophila melanogaster L-2-hydroxyglutarate dehydrogenase bound with FAD and a sulfate ion 分子名称: DODECYL-BETA-D-MALTOSIDE, FI05204p, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Yang, J, Chen, X, Jin, S, Ding, J. 登録日 2023-08-30 公開日 2023-11-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.299 Å) 主引用文献 Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria. J.Biol.Chem., 300, 2023
2BOV	Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MONO-ADP-RIBOSYLTRANSFERASE C3, ... 著者 Holbourn, K.P, Sutton, J.M, Evans, H.R, Shone, C.C, Acharya, K.R. 登録日 2005-04-14 公開日 2005-04-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Molecular Recognition of an Adp-Ribosylating Clostridium Botulinum C3 Exoenzyme by Rala Gtpase Proc.Natl.Acad.Sci.USA, 102, 2005
3DQN	Structure of the Yellow Fluorescent Protein Citrine Frozen at 500 Atmospheres: Structure 3 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
5FQL	Insights into Hunter syndrome from the structure of iduronate-2- sulfatase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Demydchuk, M, Hill, C.H, Zhou, A, Bunkoczi, G, Stein, P.E, Marchesan, D, Deane, J.E, Read, R.J. 登録日 2015-12-11 公開日 2017-01-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Insights into Hunter syndrome from the structure of iduronate-2-sulfatase. Nat Commun, 8, 2017
2BXC	Human serum albumin complexed with phenylbutazone 分子名称: 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, SERUM ALBUMIN 著者 Ghuman, J, Zunszain, P.A, Petitpas, I, Bhattacharya, A.A, Curry, S. 登録日 2005-07-26 公開日 2005-09-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. J.Mol.Biol., 353, 2005
2YQ6	Structure of Bcl-xL bound to BimSAHB 分子名称: BCL-2-LIKE PROTEIN 1, BIM BETA 5, GLYCEROL 著者 Smith, B.J, Czabotar, P.E. 登録日 2012-11-06 公開日 2012-11-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity. Acs Chem.Biol., 8, 2013

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