4PPR
| Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein DacB1 | 著者 | Prigozhin, D.M, Huizar, J.P, Mavrici, D, Alber, T, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2014-02-27 | 公開日 | 2014-11-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. Plos One, 9, 2014
|
|
2CQN
| Solution structure of the FF domain of human Formin-binding protein 3 | 分子名称: | Formin-binding protein 3 | 著者 | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-20 | 公開日 | 2005-11-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the FF domain of human Formin-binding protein 3 To be Published
|
|
6Y3J
| RING-DTC domains of Deltex 2, bound to ADP-ribose | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Probable E3 ubiquitin-protein ligase DTX2, ZINC ION | 著者 | Gabrielssen, M, Buetow, L, Huang, D.T. | 登録日 | 2020-02-18 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination. Sci Adv, 6, 2020
|
|
8ACS
| Crystal structure of FMO from Janthinobacterium svalbardensis | 分子名称: | DI(HYDROXYETHYL)ETHER, FAD-dependent oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Polidori, N, Galuska, P, Gruber, K. | 登録日 | 2022-07-06 | 公開日 | 2022-09-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Cold-Active Flavin-Dependent Monooxygenase from Janthinobacterium svalbardensis Unlocks Applications of Baeyer-Villiger Monooxygenases at Low Temperature. Acs Catalysis, 13, 2023
|
|
4P6E
| Crystal Structure of Human Cathepsin S Bound to a Non-covalent Inhibitor | 分子名称: | Cathepsin S, N-[(8R)-8-(benzoylamino)-5,6,7,8-tetrahydronaphthalen-2-yl]-4-methylpiperazine-1-carboxamide, SULFATE ION | 著者 | Wang, Y, Jadhav, P.K, Deng, G.G. | 登録日 | 2014-03-24 | 公開日 | 2014-10-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm. Acs Med.Chem.Lett., 5, 2014
|
|
4P6L
| |
8AHU
| Crystal structure of D-amino acid aminotrensferase from Haliscomenobacter hydrossis complexed with D-cycloserine | 分子名称: | Aminotransferase class IV, GLYCEROL, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate | 著者 | Matyuta, I.O, Boyko, K.M, Nikolaeva, A.Y, Bakunova, A.K, Popov, V.O, Bezsudnova, E.Y. | 登録日 | 2022-07-22 | 公開日 | 2022-08-31 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Mechanism of D-Cycloserine Inhibition of D-Amino Acid Transaminase from Haliscomenobacter hydrossis. Biochemistry Mosc., 88, 2023
|
|
3Q90
| Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1 | 分子名称: | Ras GTPase-activating protein-binding protein 1 | 著者 | Welin, M, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Ekblad, T, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, Van Der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2011-01-07 | 公開日 | 2011-02-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1 To be Published
|
|
2M7Q
| Solution structure of TAX1BP1 UBZ1+2 | 分子名称: | Tax1-binding protein 1, ZINC ION | 著者 | Ceregido, M.A, Spinola Amilibia, M, Buts, L, Bravo, J, van Nuland, N.A.J. | 登録日 | 2013-04-29 | 公開日 | 2013-12-04 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of TAX1BP1 UBZ1+2 provides insight into target specificity and adaptability. J.Mol.Biol., 426, 2014
|
|
6YDM
| beta-phosphoglucomutase from Lactococcus lactis with citrate, tris and acetate bound | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Wood, H.P, Cruz-Navarrete, F.A, Baxter, N.J, Trevitt, C.R, Robertson, A.J, Dix, S.R, Hounslow, A.M, Cliff, M.J, Waltho, J.P. | 登録日 | 2020-03-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Allomorphy as a mechanism of post-translational control of enzyme activity. Nat Commun, 11, 2020
|
|
8AH2
| Crystal structure of human 14-3-3 zeta fused to the NPM1 peptide including phosphoserine-48 | 分子名称: | 14-3-3 protein zeta/delta,Nucleophosmin | 著者 | Boyko, K.M, Kapitonova, A.A, Tugaeva, K.V, Varfolomeeva, L.A, Sluchanko, N.N. | 登録日 | 2022-07-20 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for the recognition by 14-3-3 proteins of a conditional binding site within the oligomerization domain of human nucleophosmin. Biochem.Biophys.Res.Commun., 627, 2022
|
|
5ZHV
| Crystal structure of the PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with zinc ion | 分子名称: | Transcriptional regulator, ZINC ION | 著者 | Meera, K, Pal, R.K, Arora, A, Biswal, B.K. | 登録日 | 2018-03-13 | 公開日 | 2018-10-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional characterization of the transcriptional regulator Rv3488 ofMycobacterium tuberculosisH37Rv. Biochem. J., 475, 2018
|
|
2LX9
| |
6YEZ
| Plant PSI-ferredoxin-plastocyanin supercomplex | 分子名称: | (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | 著者 | Caspy, I, Nelson, N, Shkolnisky, Y, Klaiman, D, Sheinker, A. | 登録日 | 2020-03-25 | 公開日 | 2020-09-30 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The structure of a triple complex of plant photosystem I with ferredoxin and plastocyanin. Nat.Plants, 6, 2020
|
|
6YDL
| Substrate-free beta-phosphoglucomutase from Lactococcus lactis | 分子名称: | Beta-phosphoglucomutase, MAGNESIUM ION | 著者 | Wood, H.P, Cruz-Navarrete, F.A, Baxter, N.J, Trevitt, C.R, Robertson, A.J, Dix, S.R, Hounslow, A.M, Cliff, M.J, Waltho, J.P. | 登録日 | 2020-03-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Allomorphy as a mechanism of post-translational control of enzyme activity. Nat Commun, 11, 2020
|
|
2CWO
| |
1WIQ
| |
3QFU
| Crystal structure of Yeast Hsp70 (Bip/kar2) complexed with ADP | 分子名称: | 78 kDa glucose-regulated protein homolog, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Yan, M, Li, J.Z, Sha, B.D. | 登録日 | 2011-01-22 | 公開日 | 2011-06-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor. Biochem.J., 438, 2011
|
|
3I64
| Crystal structure of an O-methyltransferase (NcsB1) from neocarzinostatin biosynthesis in complex with S-adenosyl-L-homocysteine (SAH) and 1,4-dihydroxy-2-naphthoic acid (DHN) | 分子名称: | 1,4-dihydroxy-2-naphthoic acid, GLYCEROL, O-methyltransferase, ... | 著者 | Cooke, H.A, Bruner, S.D. | 登録日 | 2009-07-06 | 公開日 | 2009-09-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Biochemistry, 48, 2009
|
|
3I53
| |
6YLU
| 14-3-3sigma in complex with BLNKpT152 phosphopeptide crystal structure | 分子名称: | 14-3-3 protein sigma, BLNKpT152, MAGNESIUM ION | 著者 | Soini, L, Leysen, S, Davis, J, Ottmann, C. | 登録日 | 2020-04-07 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | 14-3-3sigma in complex with BLNKpT152 phosphopeptide crystal structure J.Struct.Biol., 2020
|
|
4DHM
| Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... | 著者 | Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. | 登録日 | 2012-01-30 | 公開日 | 2013-07-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
|
|
4PTC
| Structure of a carboxamide compound (3) (2-{2-[(CYCLOPROPYLCARBONYL)AMINO]PYRIDIN-4-YL}-4-OXO-4H-1LAMBDA~4~,3-THIAZOLE-5-CARBOXAMIDE) to GSK3b | 分子名称: | 2-[2-(cyclopropylcarbonylamino)pyridin-4-yl]-4-methoxy-1,3-thiazole-5-carboxamide, Glycogen synthase kinase-3 beta | 著者 | Lewis, H.A, Sivaprakasam, P, Kish, K, Pokross, M, Dubowchik, G.M. | 登録日 | 2014-03-10 | 公開日 | 2015-04-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.711 Å) | 主引用文献 | Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg.Med.Chem.Lett., 25, 2015
|
|
4DHT
| Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening | 分子名称: | 14-3-3 PROTEIN SIGMA, CHLORIDE ION, GLYCEROL, ... | 著者 | Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. | 登録日 | 2012-01-30 | 公開日 | 2013-07-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
|
|
3QFD
| |