PDB: 31489 件ウェブページステータス検索Chemie searchBIRD

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6EAG	CRYSTAL STRUCTURE OF FUSION INHIBITOR JNJ-2408068 IN COMPLEX WITH HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN ESCAPE VARIANT G143S STABILIZED IN THE PREFUSION STATE 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[2-[[1-(2-azanylethyl)piperidin-4-yl]amino]-4-methyl-benzimidazol-1-yl]methyl]-6-methyl-pyridin-3-ol, D(-)-TARTARIC ACID, ... 著者 Battles, M.B, McLellan, J.S. 登録日 2018-08-03 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.302 Å) 主引用文献 Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance To be published
6EAN	CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT F488I STABILIZED IN THE PREFUSION STATE 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ... 著者 Battles, M.B, McLellan, J.S. 登録日 2018-08-03 公開日 2019-08-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance To be published
6I01	Structure of human D-glucuronyl C5 epimerase in complex with substrate 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Debarnot, C, Monneau, Y.R, Roig-Zamboni, V, Le Narvor, C, Goulet, A, Fadel, F, Vives, R.R, Bonnaffe, D, Lortat-Jacob, H, Bourne, Y. 登録日 2018-10-24 公開日 2019-04-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase. Proc.Natl.Acad.Sci.USA, 116, 2019
8U2W	Glucose-6-phosphate 1-dehydrogenase (G6PDH) from Crithidia fasciculata (NADP bound) 分子名称: Acetyl-coenzyme A synthetase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Glucose-6-phosphate 1-dehydrogenase (G6PDH) from Crithidia fasciculata (NADP bound) To be published
6E2H	Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30 分子名称: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2 著者 Joshi, M, Brunzelle, J.S, Couture, J.F. 登録日 2018-07-11 公開日 2018-08-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.236 Å) 主引用文献 Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26, 2018
8U2O	Crystal Structure of Cdk-related protein kinase 6 (PK6) from Plasmodium falciparum in complex with inhibitor TCMDC-123995 分子名称: CHLORIDE ION, GLYCEROL, N-[(4P)-2-(4-chloroanilino)-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]acetamide, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of Cdk-related protein kinase 6 (PK6) from Plasmodium falciparum in complex with inhibitor TCMDC-123995 To be published
6HDY	Crystal structure of 2-Hydroxyisobutyryl-CoA Ligase (HCL) in the postadenylation state in complex with S3-HB-AMP 分子名称: (3S)-3-HYDROXYBUTANOIC ACID, 2-hydroxyisobutyryl-CoA synthetase, SULFATE ION, ... 著者 Zahn, M, Rohwerder, T, Strater, N. 登録日 2018-08-20 公開日 2019-08-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of 2-Hydroxyisobutyric Acid-CoA Ligase Reveal Determinants of Substrate Specificity and Describe a Multi-Conformational Catalytic Cycle. J.Mol.Biol., 431, 2019
8U94	Crystal Structure of Dephospho-CoA kinase from Klebsiella aerogenes (ADP Bound) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Dephospho-CoA kinase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structure of Dephospho-CoA kinase from Klebsiella aerogenes (ADP Bound) To be published
8U99	Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Serine adduct) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Cystathionine beta-lyase, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Serine adduct) To be published
6HE6	Crystal structure of Extracellular Domain 1 (ECD1) of FtsX from S. pneumonie in complex with dodecane-trimethylamine 分子名称: Cell division protein FtsX, DODECANE-TRIMETHYLAMINE 著者 Martinez-Caballero, S, Alcorlo-Pages, M, Hermoso, J.A. 登録日 2018-08-20 公開日 2019-04-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae. Mbio, 10, 2019
6EBS	Crystal structure of Leishmania major dihydroorotate dehydrogenase mutant H174A in complex with orotate 分子名称: Dihydroorotate dehydrogenase (fumarate), FLAVIN MONONUCLEOTIDE, GLYCEROL, ... 著者 Reis, R.A.G, Pinheiro, M.P, de Souza, A.L, Hunter, W.N, Nonato, M.C. 登録日 2018-08-07 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of Leishmania major dihydroorotate dehydrogenase mutant H174A in complex with orotate To Be Published
8U2P	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) To be published
8U2X	Crystal Structure of NendoU (Uridylate-specific endoribonuclease, nsp15) from Betacoronavirus SARS-CoV-2 (H235A mutant) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Uridylate-specific endoribonuclease nsp15 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of NendoU (Uridylate-specific endoribonuclease, nsp15) from Betacoronavirus SARS-CoV-2 (H235A mutant) To be published
7OA5	RUVA COMPLEXED TO A HOLLIDAY JUNCTION. 分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*TP*CP*GP*CP*GP*AP*GP*TP*TP*CP*GP*C)-3'), DNA (5'-D(*AP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*AP*CP*T)-3'), ... 著者 Roe, S.M, Pearl, L.H. 登録日 2021-04-19 公開日 2021-04-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.378 Å) 主引用文献 Crystal structure of an octameric RuvA-Holliday junction complex Molecular Cell, 2, 1998
8U93	Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (PEG bound) 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (PEG bound) To be published
8U9A	Crystal Structure of 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase from Klebsiella aerogenes (DBH bound) 分子名称: 2,3-DIHYDROXY-BENZOIC ACID, 2,3-dihydroxybenzoate-2,3-dehydrogenase, CHLORIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase from Klebsiella aerogenes (DBH bound) To be published
6HFK	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 6.5 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... 著者 Ramon-Maiques, S, Grande Garcia, A. 登録日 2018-08-21 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.459144 Å) 主引用文献 Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
8U2S	Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (Ethyl AMP bound, P21 form) 分子名称: 5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase, CACODYLATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 A single Leishmania adenylate forming enzyme of the ANL superfamily generates both acetyl- and acetoacetyl-CoA. J.Biol.Chem., 2024
8U8W	Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound) 分子名称: CHLORIDE ION, GLYCEROL, IODIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of N-acetylneuraminate lyase (NanA) from Klebsiella aerogenes (pyruvate and halides bound) To be published
6ECC	Vlm2 thioesterase domain wild type structure 2 分子名称: Vlm2 著者 Alonzo, D.A, Schmeing, T.M. 登録日 2018-08-07 公開日 2018-12-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature, 565, 2019
6ECK	Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP 分子名称: 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, CITRATE ANION, ... 著者 Padyana, A, Tong, S. 登録日 2018-08-08 公開日 2019-12-04 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Rep, 29, 2019
8U97	Crystal Structure of Dephospho-CoA kinase from Klebsiella aerogenes (AMP-PNP bound) 分子名称: Dephospho-CoA kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-18 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of Dephospho-CoA kinase from Klebsiella aerogenes (AMP-PNP bound) To be published
8UC2	Ethylene forming enzyme (EFE) R171A variant in complex with nickel and Benzoic acid 分子名称: 1,2-ETHANEDIOL, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, BENZOIC ACID, ... 著者 Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R. 登録日 2023-09-25 公開日 2023-10-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme. Biochemistry, 63, 2024
6HG6	Clostridium beijerinckii aldo-keto reductase Cbei_3974 with NADPH 分子名称: 1,2-ETHANEDIOL, L-glyceraldehyde 3-phosphate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Scott, A.F, Cresser-Brown, J, Rizkallah, P.J, Jin, Y, Allemann, R.K. 登録日 2018-08-22 公開日 2019-05-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure and Biophysical Analysis of Furfural-Detoxifying Aldehyde Reductase from Clostridium beijerinckii. Appl.Environ.Microbiol., 85, 2019
6H8J	1.45 A resolution of Sporosarcina pasteurii urease inhibited in the presence of NBPTO 分子名称: 1,2-ETHANEDIOL, DIAMIDOPHOSPHATE, NICKEL (II) ION, ... 著者 Mazzei, L, Cianci, M, Ciurli, S. 登録日 2018-08-02 公開日 2019-06-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Insights into Urease Inhibition by N-( n-Butyl) Phosphoric Triamide through an Integrated Structural and Kinetic Approach. J.Agric.Food Chem., 67, 2019

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