6W17
 
 | | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Shaaban, M, Nolen, B.J, Chowdhury, S. | | 登録日 | 2020-03-03 | | 公開日 | 2020-08-12 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state.
Nat.Struct.Mol.Biol., 27, 2020
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6VLN
 | | Crystal structure of 4498 Fab in complex with circumsporozoite protein DND3 and anti-Kappa VHH domain | | 分子名称: | 4498 Fab heavy chain, 4498 Fab light chain, Circumsporozoite protein, ... | | 著者 | Thai, E, Scally, S.W, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | 登録日 | 2020-01-24 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
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6VM1
 | | Chloroplast ATP synthase (C3, CF1FO) | | 分子名称: | ATP synthase delta chain, chloroplastic, ATP synthase epsilon chain, ... | | 著者 | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | | 登録日 | 2020-01-27 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
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6BSX
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6VOM
 | | Chloroplast ATP synthase (R2, CF1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | | 著者 | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | | 登録日 | 2020-01-30 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
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6BTL
 | | Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor RD117 1-[2-(Piperazin-1-yl)ethyl]-5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1H-indole | | 分子名称: | 1-[2-(piperazin-1-yl)ethyl]-5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1H-indole, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Bryson, S, De Gasparo, R, Krauth-Siegel, R.L, Diederich, F, Pai, E.F. | | 登録日 | 2017-12-06 | | 公開日 | 2018-06-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.797 Å) | | 主引用文献 | Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma.
ChemMedChem, 13, 2018
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7TW2
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6C05
 | | Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | | 登録日 | 2017-12-27 | | 公開日 | 2018-03-28 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (5.15 Å) | | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
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7RDQ
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7S4Q
 | | M. xanthus encapsulin EncA bound to EncC targeting peptide | | 分子名称: | EncA, EncC targeting peptide | | 著者 | Eren, E. | | 登録日 | 2021-09-09 | | 公開日 | 2022-02-02 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
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6W2B
 | | Anomalous bromine signal reveals the position of Br-paroxetine complexed with the serotonin transporter at the central site | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 heavy chain antibody fragment, 8B6 light chain antibody fragment, ... | | 著者 | Coleman, J.A, Navratna, V, Yang, D. | | 登録日 | 2020-03-05 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (4.7 Å) | | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex.
Elife, 9, 2020
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6C3A
 | | O2-, PLP-dependent L-arginine hydroxylase RohP 4-hydroxy-2-ketoarginine complex | | 分子名称: | (4S)-5-carbamimidamido-4-hydroxy-2-oxopentanoic acid, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Hedges, J.B, Ryan, K.S. | | 登録日 | 2018-01-09 | | 公開日 | 2018-03-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase.
ACS Chem. Biol., 13, 2018
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7S20
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7S8T
 | | M. xanthus ferritin-like protein EncC | | 分子名称: | EncC, FE (III) ION | | 著者 | Eren, E. | | 登録日 | 2021-09-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural characterization of the Myxococcus xanthus encapsulin and ferritin-like cargo system gives insight into its iron storage mechanism.
Structure, 30, 2022
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1ZR7
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7UV8
 | | Rad6-Bre1 Complex | | 分子名称: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | | 著者 | Shukla, P.K, Chandrasekharan, M.B. | | 登録日 | 2022-04-29 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.
Nucleic Acids Res., 51, 2023
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7UVC
 | | Rad6(P43L)-Bre1 Complex | | 分子名称: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | | 著者 | Shukla, P.K, Chandrasekharan, M.B. | | 登録日 | 2022-04-29 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex.
Nucleic Acids Res., 51, 2023
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6W4T
 | | APE1 Y269A phosphorothioate substrate complex with abasic DNA | | 分子名称: | DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*(48Z)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase | | 著者 | Freudenthal, B.D, Hoitsma, N.M. | | 登録日 | 2020-03-11 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.
Nucleic Acids Res., 48, 2020
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5AM1
 | | ligand complex structure of soluble epoxide hydrolase | | 分子名称: | 4-oxidanylidene-N-[(1S,2R)-2-phenylcyclopropyl]spiro[3H-chromene-2,4'-piperidine]-1'-carboxamide, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... | | 著者 | Oster, L, Tapani, S, Xue, Y, Kack, H. | | 登録日 | 2015-03-08 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20, 2015
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6C0Y
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6C89
 | | NDM-1 Beta-Lactamase Exhibits Differential Active Site Sequence Requirements for the Hydrolysis of Penicillin versus Carbapenem Antibiotics | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | | 著者 | Palzkill, T, Sun, Z, Sankaran, B. | | 登録日 | 2018-01-24 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.75006151 Å) | | 主引用文献 | Differential active site requirements for NDM-1 beta-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics.
Nat Commun, 9, 2018
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6VIE
 | | Structure of caspase-1 in complex with gasdermin D | | 分子名称: | Caspase-1 subunit p10, Caspase-1 subunit p20, Gasdermin-D | | 著者 | Liu, Z, Xiao, T.S. | | 登録日 | 2020-01-13 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.
Immunity, 53, 2020
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6VJ7
 | | Crystal structure of red kidney bean purple acid phosphatase in complex with adenosine 5'-(beta,gamma imido)triphosphate | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Feder, D, Schenk, G, Guddat, L.W, McGeary, R.P, Mitic, N, Furtado, A, Schulz, B.L, Henry, R.J, Schmidt, S. | | 登録日 | 2020-01-15 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural elements that modulate the substrate specificity of plant purple acid phosphatases: Avenues for improved phosphorus acquisition in crops.
Plant Sci., 294, 2020
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4TN8
 | | Crystal structure of Thermus Thermophilus thioredoxin solved by sulfur SAD using Swiss Light Source data | | 分子名称: | CHLORIDE ION, Thioredoxin | | 著者 | Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2014-06-03 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
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7QWL
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