PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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5M73	Structure of the human SRP S domain with SRP72 RNA-binding domain 分子名称: GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ... 著者 Becker, M.M.M, Wild, K, Sinning, I. 登録日 2016-10-26 公開日 2016-12-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction. Nucleic Acids Res., 45, 2017
6SMY	Crystal structure of SLA Reductase YihU from E. Coli with NADH and product DHPS 分子名称: (2~{S})-2,3-bis(oxidanyl)propane-1-sulfonic acid, 3-sulfolactaldehyde reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Sharma, M, Davies, G.J. 登録日 2019-08-23 公開日 2020-08-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Dynamic Structural Changes Accompany the Production of Dihydroxypropanesulfonate by Sulfolactaldehyde Reductase Acs Catalysis, 2020
5M7Y	Crystal structure of GH125 1,6-alpha-mannosidase mutant from Clostridium perfringens in complex with 1,6-alpha-mannotriose 分子名称: 1,6-alpha-mannosidase, MAGNESIUM ION, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose 著者 Males, A, Alonso-Gil, S, Fernandes, P, Williams, S.J, Rovira, C, Davies, G.J. 登録日 2016-10-28 公開日 2016-11-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Computational Design of Experiment Unveils the Conformational Reaction Coordinate of GH125 alpha-Mannosidases. J. Am. Chem. Soc., 139, 2017
5MGG	Crystal Structure of BAZ2B bromodomain in complex with 4-chloropyridine derivative 3 分子名称: 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2B 著者 Lolli, G, Spiliotopoulos, D, Caflisch, A. 登録日 2016-11-21 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
6SJT	Crystal structure of the Legionella pneumophila type II secretion system substrate NttC 分子名称: NttC 著者 Portlock, T.J, Rehman, S, Garnett, J.A. 登録日 2019-08-13 公開日 2020-05-20 最終更新日 2020-07-22 実験手法 X-RAY DIFFRACTION (3.103 Å) 主引用文献 Structure, Dynamics and Cellular Insight Into Novel Substrates of theLegionella pneumophilaType II Secretion System. Front Mol Biosci, 7, 2020
5MGJ	Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridine derivative 1 分子名称: Bromodomain adjacent to zinc finger domain protein 2A, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate 著者 Lolli, G, Spiliotopoulos, D, Caflisch, A. 登録日 2016-11-21 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGL	Crystal Structure of BAZ2A bromodomain in complex with 4-chloropyridine derivative 3 分子名称: 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A 著者 Lolli, G, Spiliotopoulos, D, Caflisch, A. 登録日 2016-11-21 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.651 Å) 主引用文献 Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
7AUD	Structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Bloom syndrome protein,Bloom syndrome protein, DNA (5'-D(*GP*TP*AP*CP*CP*CP*GP*AP*TP*GP*TP*GP*T)-3'), ... 著者 Chen, X, Oliver, A.W. 登録日 2020-11-02 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. Elife, 10, 2021
6SPA	A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 IN C2 SPACE GROUP 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, SULFATE ION, ... 著者 Shahid, M, Chantadul, V, Amporndanai, K, Wright, G, Antonyuk, S, Hasnain, S. 登録日 2019-08-31 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3, 2020
7AP4	Thermus thermophilus Aspartyl-tRNA Synthetase in Complex with Compound AspS7HMDDA 分子名称: (3~{S})-3-azanyl-4-[[(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxysulfonylamino]-4-oxidanylidene-butanoic acid, Aspartate--tRNA(Asp) ligase 著者 De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. 登録日 2020-10-15 公開日 2020-12-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
7B1A	Myosin-II-AA mutant motor domain 分子名称: 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Ewert, W, Preller, M. 登録日 2020-11-24 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release. Int J Mol Sci, 22, 2020
6SQ2	Structure of a phosphomimetic switch 2 variant of Rab8a in complex with the phospho-Rab binding domain of RILPL2 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RILP-like protein 2, ... 著者 Khan, A.R, Waschbusch, D. 登録日 2019-09-03 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.684 Å) 主引用文献 Structure of a phosphomimetic switch 2 variant of Rab8a in complex with the phospho-Rab binding domain of RILPL2 To Be Published
7AQ5	Pseudomonas stutzeri nitrous oxide reductase mutant, H583N 分子名称: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Zhang, L, Bill, E, Kroneck, P.M.H, Einsle, O. 登録日 2020-10-20 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Histidine-Gated Proton-Coupled Electron Transfer to the Cu A Site of Nitrous Oxide Reductase. J.Am.Chem.Soc., 143, 2021
6SQL	Crystal structure of M. tuberculosis InhA in complex with NAD+ and N-(3-(aminomethyl)phenyl)-5-chloro-3-methylbenzo[b]thiophene-2-sulfonamide 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ~{N}-[3-(aminomethyl)phenyl]-5-chloranyl-3-methyl-1-benzothiophene-2-sulfonamide 著者 Mendes, V, Sabbah, M, Coyne, A.G, Abell, C, Blundell, T.L. 登録日 2019-09-04 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Fragment-Based Design ofMycobacterium tuberculosisInhA Inhibitors. J.Med.Chem., 63, 2020
7B33	MST3 in complex with MRIA11 分子名称: 1,2-ETHANEDIOL, 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[4-[6-[bis(fluoranyl)methyl]pyridin-2-yl]-2-chloranyl-phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one, Serine/threonine-protein kinase 24 著者 Tesch, R, Rak, M, Joerger, A.C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-11-28 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors. J.Med.Chem., 64, 2021
5MCM	Radiation damage to GH7 Family Cellobiohydrolase from Daphnia pulex: Dose (DWD) 20.6 MGy 分子名称: Cellobiohydrolase CHBI, GLYCEROL, SULFATE ION 著者 Bury, C.S, McGeehan, J.E, Ebrahim, A, Garman, E.F. 登録日 2016-11-10 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 OH cleavage from tyrosine: debunking a myth. J Synchrotron Radiat, 24, 2017
6SR9	Crystal structure of glutathione transferase Omega 2C from Trametes versicolor in complex with oxyresveratrol 分子名称: GLUTATHIONE, Uncharacterized protein, trans-oxyresveratrol 著者 Schwartz, M, Favier, F, Didierjean, C. 登録日 2019-09-05 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.845 Å) 主引用文献 Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches. Fungal Genet Biol., 148, 2021
5MEB	Crystal structure of yeast Cdt1 C-terminal domain 分子名称: Cell division cycle protein CDT1, SULFATE ION 著者 Pye, V.E, Frigola, J, Diffley, J.F.X, Cherepanov, P. 登録日 2016-11-14 公開日 2017-05-17 最終更新日 2017-07-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Cdt1 stabilizes an open MCM ring for helicase loading. Nat Commun, 8, 2017
5MEH	Crystal structure of alpha-1,2-mannosidase from Caulobacter K31 strain in complex with 1-deoxymannojirimycin 分子名称: 1-DEOXYMANNOJIRIMYCIN, ACETATE ION, CALCIUM ION, ... 著者 Males, A, Davies, G.J. 登録日 2016-11-14 公開日 2016-12-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Conformational Behaviour of Azasugars Based on Mannuronic Acid. Chembiochem, 18, 2017
5MEL	Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with Glc-alpha-1,3-(3R,4R,5R)-5-(hydroxymethyl)cyclohex-1,2-ene-3,4-diol 分子名称: (1~{R},2~{R},6~{R})-6-(hydroxymethyl)cyclohex-3-ene-1,2-diol, ACETATE ION, Glycosyl hydrolase family 71, ... 著者 Petricevic, M, Sobala, L.F, Fernandes, P.Z, Raich, L, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. 登録日 2016-11-15 公開日 2017-01-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-alpha-1,2-Mannanase. J. Am. Chem. Soc., 139, 2017
7AH2	Crystal structure of Zebrafish MDM2 RING domain homodimer 分子名称: E3 ubiquitin-protein ligase Mdm2, ZINC ION 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-24 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.872 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
5MER	Human Leukocyte Antigen A02 presenting ILAKFLHEL 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, ... 著者 Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K. 登録日 2016-11-16 公開日 2016-12-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292, 2017
5MJH	X-ray generated oxyferrous/water mixed complex of DtpA from Streptomyces lividans 分子名称: Dye type peroxidase A, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE 著者 Moreno Chicano, T, Chaplin, A.K, Worrall, J.A.R, Strange, R.W, Hough, M.A. 登録日 2016-12-01 公開日 2017-05-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Photoreduction and validation of haem-ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction. IUCrJ, 4, 2017
7APF	Crystal structure of JAK3 in complex with FM601 (compound 10a) 分子名称: 1,2-ETHANEDIOL, 1-phenylurea, 3-[3-(propanoylamino)phenyl]-1~{H}-pyrrolo[2,3-b]pyridine-5-carboxamide, ... 著者 Chaikuad, A, Forster, M, Gehringer, M, Laufer, S, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-10-16 公開日 2020-12-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK. Int J Mol Sci, 21, 2020
5MFR	The crystal structure of E. coli Aminopeptidase N in complex with 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one 分子名称: Aminopeptidase N, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Peng, G, Olieric, V, McEwen, A.G, Schmitt, C, Albrecht, S, Cavarelli, J, Tarnus, C. 登録日 2016-11-18 公開日 2017-04-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis. Proteins, 85, 2017

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