6SPA

A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 IN C2 SPACE GROUP

Summary for 6SPA

Entry DOI	10.2210/pdb6spa/pdb
Descriptor	Superoxide dismutase [Cu-Zn], ZINC ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	a4v sod1 mutant, oxidoreductase, mnd, als
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	96961.72
Authors	Shahid, M.,Chantadul, V.,Amporndanai, K.,Wright, G.,Antonyuk, S.,Hasnain, S. (deposition date: 2019-08-31, release date: 2020-03-18, Last modification date: 2024-01-24)
Primary citation	Chantadul, V.,Wright, G.S.A.,Amporndanai, K.,Shahid, M.,Antonyuk, S.V.,Washbourn, G.,Rogers, M.,Roberts, N.,Pye, M.,O'Neill, P.M.,Hasnain, S.S. Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3:97-97, 2020 Cited by PubMed: 32139772 DOI: 10.1038/s42003-020-0826-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation