PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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7HBR	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with AS-5576 分子名称: 4-(4-fluorophenyl)-1H-pyrazole, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7H9P	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12541 分子名称: 4-phenoxyphenol, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7H9S	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with FS-3027 分子名称: Heat shock protein HSP 90-alpha, [2-(4-ethylpiperazin-1-yl)phenyl]methanol 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBM	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13278 分子名称: Heat shock protein HSP 90-alpha, N-cycloheptyl-N'-(2-hydroxyethyl)thiourea 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6CIJ	Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A) 分子名称: CALCIUM ION, DNA (30-MER), DNA (41-MER), ... 著者 Chen, X, Kim, M, Chuenchor, W, Cui, Y, Zhang, X, Zhou, Z.H, Gellert, M, Yang, W. 登録日 2018-02-24 公開日 2018-04-25 最終更新日 2025-05-14 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
7HBY	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 9R-0342 分子名称: Heat shock protein HSP 90-alpha, N-[(4-fluorophenyl)methyl]-1H-pyrrole-2-carboxamide 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7H9Y	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with NH-0224 分子名称: 1-[5-chloro-4-(difluoromethyl)pyridin-2-yl]piperazine, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6CY8	Crystal structure of FAD-dependent dehydrogenase 分子名称: 4'-PHOSPHOPANTETHEINE, Alpha/beta hydrolase fold protein, Butyryl-CoA dehydrogenase, ... 著者 Agarwal, V. 登録日 2018-04-05 公開日 2019-01-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.729 Å) 主引用文献 Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein. Biochemistry, 58, 2019
7HB0	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12780 分子名称: 2-[(oxan-4-yl)oxy]aniline, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBA	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13425 分子名称: 4-(4,5-dichloro-1H-imidazol-1-yl)aniline, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7TDN	CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain 分子名称: COP-3 Fab Heavy chain, COP-3 Fab Light chain, Claudin-4, ... 著者 Vecchio, A.J. 登録日 2022-01-01 公開日 2022-02-09 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J.Biol.Chem., 298, 2022
7TDM	CryoEM Structure of sFab COP-2 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain 分子名称: COP-2 Fab Heavy chain, COP-2 Fab Light chain, Claudin-4, ... 著者 Vecchio, A.J. 登録日 2022-01-01 公開日 2022-02-09 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J.Biol.Chem., 298, 2022
7Q59	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma factor SigB 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Brodolin, K. 登録日 2021-11-03 公開日 2022-11-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.36 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
7HAJ	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with PS-4122 分子名称: 1-methyl-1H-indole-6-carboxylic acid, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HBN	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13145 分子名称: Heat shock protein HSP 90-alpha, {2-[(oxan-4-yl)oxy]phenyl}methanol 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6VHW	Klebsiella oxytoca NpsA N-terminal subdomain in complex with 3-hydroxybenzoyl-AMSN 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-deoxy-5'-{[(3-hydroxybenzene-1-carbonyl)sulfamoyl]amino}adenosine, BROMIDE ION, ... 著者 Kreitler, D.F, Gulick, A.M. 登録日 2020-01-10 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca. Acs Infect Dis., 6, 2020
7HA6	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with DH-0718 分子名称: 6-bromo-1-methyl-3,4-dihydroquinolin-2(1H)-one, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAC	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13324 分子名称: 3-(4-tert-butylphenyl)-3-oxopropanamide, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6CJV	Carbonic anhydrase IX-mimic in complex with sucralose 分子名称: 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose, Carbonic anhydrase 2, ZINC ION 著者 Lomelino, C.L, Murray, A.B, McKenna, R. 登録日 2018-02-26 公開日 2018-08-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.547 Å) 主引用文献 Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose. ACS Med Chem Lett, 9, 2018
7HAX	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13909 分子名称: (3aR,7aS)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAS	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr12355 分子名称: Heat shock protein HSP 90-alpha, [6-(pyrrolidin-1-yl)pyridin-2-yl]methanol 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HC3	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with 3T-0629 分子名称: 2,3-dimethylpyrido[2,3-b]pyrazine, Heat shock protein HSP 90-alpha 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
7HAY	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr14271 分子名称: Heat shock protein HSP 90-alpha, N-(2-{[(4-chlorophenyl)methyl]sulfanyl}ethyl)furan-2-carboxamide 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025
6US8	Influenza A M2 proton channel wild type TM domain bound to S-rimantadine 分子名称: (1S)-1-[(3R,5R,7R)-tricyclo[3.3.1.1~3,7~]decan-1-yl]ethan-1-amine, CHLORIDE ION, Matrix protein 2 著者 Thomaston, J.L, DeGrado, W.F. 登録日 2019-10-25 公開日 2020-10-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Rimantadine Binds to and Inhibits the Influenza A M2 Proton Channel without Enantiomeric Specificity. Biochemistry, 2021
7HAA	PanDDA analysis group deposition -- Crystal structure of HSP90N in complex with Fr13279 分子名称: Heat shock protein HSP 90-alpha, N-(5-chloro-2-methoxyphenyl)thiourea 著者 Huang, L, Wang, W, Zhu, Z, Li, Q, Li, M, Zhou, H, Xu, Q, Wen, W, Wang, Q, Yu, F. 登録日 2024-07-10 公開日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening. Iucrj, 12, 2025

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