6WK1
 
 | | SETD3 in Complex with an Actin Peptide with His73 Replaced with Methionine | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Actin, ... | | 著者 | Dai, S, Horton, J.R, Cheng, X. | | 登録日 | 2020-04-15 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Characterization of SETD3 methyltransferase-mediated protein methionine methylation.
J.Biol.Chem., 295, 2020
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5W65
 | | RNA polymerase I Initial Transcribing Complex State 2 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Han, Y, He, Y. | | 登録日 | 2017-06-16 | | 公開日 | 2017-08-02 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Elife, 6, 2017
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6RUO
 | | RNA Polymerase I Open Complex conformation 1 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Mueller, C.W, Sadian, Y, Tafur, L. | | 登録日 | 2019-05-28 | | 公開日 | 2019-12-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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6WT4
 | | Structure of a bacterial STING receptor from Flavobacteriaceae sp. in complex with 3',3'-cGAMP | | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Bacterial STING, SULFATE ION | | 著者 | Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J. | | 登録日 | 2020-05-01 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | STING cyclic dinucleotide sensing originated in bacteria.
Nature, 586, 2020
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6RKW
 | | CryoEM structure of the complete E. coli DNA Gyrase complex bound to a 130 bp DNA duplex | | 分子名称: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA (58-MER), DNA (62-MER), ... | | 著者 | Vanden Broeck, A, Lamour, V. | | 登録日 | 2019-04-30 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex.
Nat Commun, 10, 2019
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5W64
 | | RNA Polymerase I Initial Transcribing Complex State 1 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Han, Y, He, Y. | | 登録日 | 2017-06-16 | | 公開日 | 2017-07-26 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Elife, 6, 2017
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6KYT
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6X06
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6KX6
 | | Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound | | 分子名称: | Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide | | 著者 | Miller, S.A, Aikawa, Y, Hirota, T. | | 登録日 | 2019-09-10 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
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6RQG
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6RRD
 | | RNA Polymerase I Pre-initiation complex DNA opening intermediate 1 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Mueller, C.W, Sadian, Y, Tafur, L. | | 登録日 | 2019-05-17 | | 公開日 | 2019-12-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular insight into RNA polymerase I promoter recognition and promoter melting.
Nat Commun, 10, 2019
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7LO5
 | | cryoEM structure DrdV-DNA complex | | 分子名称: | CALCIUM ION, DNA (27-MER), DNA (28-MER), ... | | 著者 | Shen, B.W, Stoddard, B.L. | | 登録日 | 2021-02-09 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM.
Structure, 29, 2021
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6S6U
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6WDP
 | | Interleukin 12 receptor subunit beta-1 | | 分子名称: | GLYCEROL, Interleukin-12 receptor subunit beta-1, SULFATE ION | | 著者 | Spangler, J.B, Thomas, C, Jude, K.M, Garcia, K.C. | | 登録日 | 2020-04-01 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-12-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.
Cell, 184, 2021
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6WDQ
 | | IL23/IL23R/IL12Rb1 signaling complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, ... | | 著者 | Jude, K.M, Ely, L.K, Glassman, C.R, Thomas, C, Spangler, J.B, Lupardus, P.J, Garcia, K.C. | | 登録日 | 2020-04-01 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.
Cell, 184, 2021
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6L0Z
 | | The crystal structure of Salmonella enterica sugar-binding protein MalE | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,5-anhydro-D-glucitol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of Salmonella enterica sugar-binding protein MalE
To Be Published
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6L7U
 | | Crystal structure of FKRP in complex with Ba ion, Ba-SAD data | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BARIUM ION, Fukutin-related protein, ... | | 著者 | Kuwabara, N. | | 登録日 | 2019-11-03 | | 公開日 | 2020-01-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.
Nat Commun, 11, 2020
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6WLP
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6RKS
 | | E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 without TOPRIM insertion | | 分子名称: | (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... | | 著者 | Vanden Broeck, A, Lamour, V. | | 登録日 | 2019-04-30 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex.
Nat Commun, 10, 2019
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6WW9
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6RLU
 | | Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine | | 分子名称: | 5'-O-(N-(L-seryl)-sulfamoyl)cytidine, GLYCEROL, MALONATE ION, ... | | 著者 | Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. | | 登録日 | 2019-05-02 | | 公開日 | 2020-01-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
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3A25
 | | Crystal structure of P. horikoshii TYW2 in complex with AdoMet | | 分子名称: | S-ADENOSYLMETHIONINE, Uncharacterized protein PH0793 | | 著者 | Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2009-04-28 | | 公開日 | 2009-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Proc.Natl.Acad.Sci.USA, 106, 2009
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6WTG
 | | SdeA DUB Domain in complex with Ubiquitin | | 分子名称: | Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA | | 著者 | Kenny, S, Sheedlo, M, Das, C. | | 登録日 | 2020-05-02 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA.
Biochemistry, 60, 2021
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6WWA
 | | Crystal structure of human SHLD2-SHLD3-REV7 complex | | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera | | 著者 | Xie, W, Patel, D.J. | | 登録日 | 2020-05-08 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6L7T
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