4RGV
 
 | | Crystal structure of the Methanocaldococcus jannaschii G1PDH | | 分子名称: | Glycerol-1-phosphate dehydrogenase, MAGNESIUM ION, ZINC ION | | 著者 | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | | 登録日 | 2014-09-30 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
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6BOW
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4RHA
 | | Structure of the C-terminal domain of outer-membrane protein OmpA from Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, Outer membrane protein A, ... | | 著者 | Cuff, M.E, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-10-01 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
Protein Sci., 26, 2017
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8SV1
 | | Caspase-1 complex with interleukin-18 | | 分子名称: | Caspase-1, Interleukin-18 | | 著者 | Dong, Y, Pascal, D, Jon, K, Wu, H. | | 登録日 | 2023-05-15 | | 公開日 | 2024-05-08 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural transitions enable interleukin-18 maturation and signaling.
Immunity, 57, 2024
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6BTW
 | | Crystal Structure of the Human vaccinia-related kinase bound to a phenyl-pteridinone inhibitor | | 分子名称: | 2-[(3,5-difluoro-4-hydroxyphenyl)amino]-8-phenyl-7,8-dihydropteridin-6(5H)-one, CHLORIDE ION, GLYCEROL, ... | | 著者 | Counago, R.M, dos Reis, C.V, de Souza, G.P, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) | | 登録日 | 2017-12-07 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the Human vaccinia-related kinase bound to a phenyl-pteridinone inhibitor
To Be Published
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4RAL
 | | Crystal structure of insulin degrading enzyme in complex with macrophage inflammatory protein 1 beta | | 分子名称: | C-C motif chemokine 4, Insulin-degrading enzyme, ZINC ION | | 著者 | Liang, W.G, Ren, M, Guo, Q, Tang, W.J. | | 登録日 | 2014-09-10 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.148 Å) | | 主引用文献 | Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
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5AI8
 | | ligand complex structure of soluble epoxide hydrolase | | 分子名称: | 6-methyl-1,3-benzothiazol-2-amine, BIFUNCTIONAL EPOXIDE HYDROLASE 2, GLYCEROL, ... | | 著者 | Oster, L, Tapani, S, Xue, Y, Kack, H. | | 登録日 | 2015-02-12 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20, 2015
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4ZWX
 | | Engineered Carbonic Anhydrase IX mimic in complex with glucosyl sulfamate inhibitor | | 分子名称: | (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-{[5-(sulfamoyloxy)pentyl]sulfamoyl}-D-allitol, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Mahon, B.P, Lomelino, C.L, Salguero, A.L, McKenna, R. | | 登録日 | 2015-05-19 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates.
J.Med.Chem., 58, 2015
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1YRU
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1YRT
 | | Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin | | 分子名称: | Bifunctional hemolysin-adenylate cyclase, CALCIUM ION, Calmodulin | | 著者 | Guo, Q, Shen, Y, Lee, Y.S, Gibbs, C.S, Mrksich, M, Tang, W.J. | | 登録日 | 2005-02-04 | | 公開日 | 2006-01-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24, 2005
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7Q4U
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6BYM
 | | Crystal structure of the sterol-bound second StART domain of yeast Lam4 | | 分子名称: | 25-HYDROXYCHOLESTEROL, Sterol-binding protein | | 著者 | Jentsch, J.A, Kiburu, I.N, Wu, J, Pandey, K, Boudker, O, Menon, A.K. | | 登録日 | 2017-12-20 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of sterol binding and transport by a yeast StARkin domain.
J. Biol. Chem., 293, 2018
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6UT8
 | | Refined half-complex from tetradecameric assembly of Thermococcus gammatolerans McrB AAA+ hexamers with bound McrC | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase subunit of restriction endonuclease, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Niu, Y, Suzuki, H, Hosford, C.J, Chappie, J.S, Walz, T. | | 登録日 | 2019-10-29 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes.
Nat Commun, 11, 2020
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5AHX
 | | Apo structure of soluble epoxide hydrolase | | 分子名称: | BIFUNCTIONAL EPOXIDE HYDROLASE 2, GLYCEROL, SULFATE ION | | 著者 | Oster, L, Tapani, S, Xue, Y, Kack, H. | | 登録日 | 2015-02-10 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20, 2015
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5AK3
 | | ligand complex structure of soluble epoxide hydrolase | | 分子名称: | BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, INDAN-2-AMINE, ... | | 著者 | Oster, L, Tapani, S, Xue, Y, Kack, H. | | 登録日 | 2015-03-02 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20, 2015
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1YTG
 | | SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT | | 分子名称: | HIV PROTEASE, PEPTIDE PRODUCT | | 著者 | Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M. | | 登録日 | 1996-08-01 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
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5ALH
 | | ligand complex structure of soluble epoxide hydrolase | | 分子名称: | 4-[[(2-methoxy-5-methyl-phenyl)sulfonylamino]methyl]-4-phenyl-N-(p-tolylmethyl)piperidine-1-carboxamide, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... | | 著者 | Oster, L, Tapani, S, Xue, Y, Kack, H. | | 登録日 | 2015-03-08 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20, 2015
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5AKI
 | | ligand complex structure of soluble epoxide hydrolase | | 分子名称: | BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | 著者 | Oster, L, Tapani, S, Xue, Y, Kack, H. | | 登録日 | 2015-03-03 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Successful Generation of Structural Information for Fragment-Based Drug Discovery.
Drug Discov Today, 20, 2015
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7QLJ
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1YTJ
 | | SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT | | 分子名称: | PEPTIDE PRODUCT, SIV PROTEASE | | 著者 | Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M. | | 登録日 | 1996-08-01 | | 公開日 | 1997-03-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
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1YTH
 | | SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT | | 分子名称: | HIV PROTEASE, PEPTIDE PRODUCT | | 著者 | Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M. | | 登録日 | 1996-08-01 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
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6C5R
 | | Crystal structure of the soluble domain of the mitochondrial calcium uniporter | | 分子名称: | calcium uniporter | | 著者 | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | | 登録日 | 2018-01-16 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.09608316 Å) | | 主引用文献 | X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
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1YUF
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6BOF
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6V0B
 | | Unliganded ELIC in POPC-only nanodiscs. | | 分子名称: | Gamma-aminobutyric-acid receptor subunit beta-1 | | 著者 | Grosman, C, Kumar, P. | | 登録日 | 2019-11-18 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer.
Proc.Natl.Acad.Sci.USA, 117, 2020
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