PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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2UPJ	HIV-1 PROTEASE COMPLEX WITH U100313 ([3-[[3-[CYCLOPROPYL [4-HYDROXY-2OXO-6-[1-(PHENYLMETHYL)PROPYL]-2H-PYRAN-3-YL] METHYL]PHENYL]AMINO]-3-OXO-PROPYL]CARBAMIC ACID TERT-BUTYL ESTER) 分子名称: HIV-1 PROTEASE, [2-(3-{[6-(1-BENZYL-PROPYL)-4-HYDROXY-2-OXO-2H-PYRAN-3-YL]-CYCLOPROPYL-METHYL}-PHENYLCARBAMOYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER 著者 Watenpaugh, K.D, Mulichak, A.M, Janakiraman, M.N. 登録日 1996-03-04 公開日 1996-10-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors. J.Med.Chem., 38, 1995
4LYI	Crystal Structure of apo-BRD4(1) 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, IODIDE ION, ... 著者 Wohlwend, D. 登録日 2013-07-31 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew.Chem.Int.Ed.Engl., 52, 2013
7KRF	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with (E)-4-(3-(2-cyanovinyl)-5-fluorophenoxy)-3-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenyl sulfurofluoridate (JLJ710) 分子名称: 4-{3-[(E)-2-cyanoethenyl]-5-fluorophenoxy}-3-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenyl sulfurofluoridate, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... 著者 Bertoletti, N, Ippolito, J.A, Jorgensen, W.L, Anderson, K.S. 登録日 2020-11-19 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. Acs Med.Chem.Lett., 12, 2021
8TPX	Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 3 in complex with antibody fragment 1B2: trans-oriented 1B2 and ACP 分子名称: Antibody Fragment 1B2, Heavy Chain, Light Chain, ... 著者 Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. 登録日 2023-08-05 公開日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis To Be Published
2DJG	Re-determination of the native structure of human dipeptidyl peptidase I (cathepsin C) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Dipeptidyl-peptidase 1, ... 著者 Molgaard, A, Arnau, J, Lauritzen, C, Larsen, S, Petersen, G, Pedersen, J. 登録日 2006-04-02 公開日 2006-11-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The crystal structure of human dipeptidyl peptidase I (cathepsin C) in complex with the inhibitor Gly-Phe-CHN2 Biochem.J., 401, 2007
7KJ4	SARS-CoV-2 Spike Glycoprotein with three ACE2 Bound 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B. 登録日 2020-10-25 公開日 2020-11-11 最終更新日 2021-02-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat.Struct.Mol.Biol., 28, 2021
1N6D	Tricorn protease in complex with tetrapeptide chloromethyl ketone derivative 分子名称: DECANE, RVRK, Tricorn protease 著者 Kim, J.-S, Groll, M, Huber, R, Brandstetter, H. 登録日 2002-11-10 公開日 2002-12-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Navigation Inside a Protease: Substrate Selection and Product Exit in the Tricorn Protease from Thermoplasma acidophilum J.Mol.Biol., 324, 2002
7KSL	Substrate-free human mitochondrial LONP1 分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial 著者 Shin, M, Watson, E.R, Song, A.S, Mindrebo, J.T, Novick, S.R, Griffin, P, Wiseman, R.L, Lander, G.C. 登録日 2020-11-23 公開日 2020-12-09 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of the human LONP1 protease reveal regulatory steps involved in protease activation. Nat Commun, 12, 2021
2DKA	Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, in the apo-form 分子名称: Phosphoacetylglucosamine mutase 著者 Nishitani, Y, Maruyama, D, Nonaka, T, Kita, A, Fukami, T.A, Mio, T, Yamada-Okabe, H, Yamada-Okabe, T, Miki, K. 登録日 2006-04-07 公開日 2006-05-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystal Structures of N-Acetylglucosamine-phosphate Mutase, a Member of the {alpha}-D-Phosphohexomutase Superfamily, and Its Substrate and Product Complexes. J.Biol.Chem., 281, 2006
7QJW	In vitro assembled tau filaments with structures like chronic traumatic encephalopathy type II (8a) 分子名称: Microtubule-associated protein tau 著者 Lovestam, S, Scheres, S.H.W. 登録日 2021-12-17 公開日 2022-01-19 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy. Elife, 11, 2022
8TOP	Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP glycoprotein gp41, ... 著者 Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D. 登録日 2023-08-03 公開日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide To Be Published
3FGD	Drugscore FP: Thermoylsin in complex with fragment. 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Englert, L, Heine, A, Klebe, G. 登録日 2008-12-05 公開日 2009-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Drugscore FP: Profiling Protein-Ligand Interactions using Fingerprint Simplicity paired with Knowledge-Based Potential Fields To be Published
4MHV	Crystal structure of the PNT domain of human ETS2 分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ... 著者 Newman, J.A, Cooper, C.D.O, Krojer, T, Shrestha, L, Burgess-brown, N, Arrowsmith, C.H, Bountra, C, Edwards, A, Gileadi, O. 登録日 2013-08-30 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of the PNT domain of human ETS2 To be Published
8TOZ	Class III PreQ1 riboswitch double mutant U8C/A85G 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, Class-III preQ1 riboswitch 著者 Srivastava, Y, Jenkins, J.L, Wedekind, J.E. 登録日 2023-08-04 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 New insights into Class III PreQ1 metabolite binding To Be Published
2UVR	Crystal structures of mutant Dpo4 DNA polymerases with 8-oxoG containing DNA template-primer constructs 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*C)-3', 5'-D(*TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP *CP*TP*TP*CP*CP*CP*CP*C)-3', ... 著者 Irimia, A, Egli, M. 登録日 2007-03-13 公開日 2007-05-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Hydrogen Bonding of 7,8-Dihydro-8-Oxodeoxyguanosine with a Charged Residue in the Little Finger Domain Determines Miscoding Events in Sulfolobus Solfataricus DNA Polymerase Dpo4. J.Biol.Chem., 282, 2007
5C8D	Crystal structure of full-length Thermus thermophilus CarH bound to adenosylcobalamin (dark state) 分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Light-dependent transcriptional regulator CarH 著者 Jost, M, Drennan, C.L. 登録日 2015-06-25 公開日 2015-09-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for gene regulation by a B12-dependent photoreceptor. Nature, 526, 2015
3F5W	KcsA Potassium channel in the open-inactivated state with 32 A opening at T112 分子名称: Antibody heavy chain, Antibody light chain, POTASSIUM ION, ... 著者 Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E. 登録日 2008-11-04 公開日 2010-05-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 KcsA Potassium channel in the open-inactivated state with 32 A opening at T112 TO BE PUBLISHED
8TNF	Crystal structure of sulfohexulose-1-phosphate aldolase from Paracoccus onubensis strain Merri 分子名称: DUF2090 domain-containing protein 著者 Lee, M. 登録日 2023-08-01 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A patchwork pathway for catabolism degradation of the sulfosugar sulfofucose To Be Published
7L0W	Human Bocavirus 1 (pH 5.5) 分子名称: VP2 著者 Luo, M, Mietzsch, M, Agbandje-McKenna, M. 登録日 2020-12-13 公開日 2021-01-27 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 pH-Induced Conformational Changes of Human Bocavirus Capsids. J.Virol., 95, 2021
5C9P	Crystal structure of recombinant PLL lectin complexed with L-fucose from Photorhabdus luminescens at 1.75 A resolution 分子名称: GLYCEROL, PLL lectin, alpha-L-fucopyranose 著者 Kumar, A, Sykorova, P, Demo, G, Dobes, P, Hyrsl, P, Wimmerova, M. 登録日 2015-06-28 公開日 2016-10-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A Novel Fucose-binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure. J.Biol.Chem., 291, 2016
8TPW	Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 3 in complex with antibody fragment 1B2: cis-oriented 1B2 and ACP 分子名称: Antibody Fragment 1B2, Heavy Chain, Light Chain, ... 著者 Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. 登録日 2023-08-05 公開日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis To Be Published
4HIW	Crystal structure of R34/53A, H112W mutant of borna disease virus matrix protein 分子名称: Matrix protein 著者 Dautel, P, Kolenko, P, Stubbs, M.T. 登録日 2012-10-12 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Matrix protein variants provide support for alternative borna disease virus infection pathway To be Published
7KUV	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Acetate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2020-11-25 公開日 2021-02-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10. Biochemistry, 60, 2021
3FOG	Crystal structure of the PX domain of sorting nexin-17 (SNX17) 分子名称: SODIUM ION, Sorting nexin-17 著者 Wisniewska, M, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Siponen, M.I, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Schueler, H, Structural Genomics Consortium (SGC) 登録日 2008-12-30 公開日 2009-01-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the PX domain of sorting nexin-17 (SNX17) TO BE PUBLISHED
7Q5R	Protein community member pyruvate dehydrogenase complex E2 core from C. thermophilum 分子名称: Acetyltransferase component of pyruvate dehydrogenase complex 著者 Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. 登録日 2021-11-04 公開日 2022-02-02 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022

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