8TPX

Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 3 in complex with antibody fragment 1B2: trans-oriented 1B2 and ACP

Summary for 8TPX

• Entry DOI: 10.2210/pdb8tpx/pdb
• EMDB information: 41495 41496
• Descriptor: EryAII,EryAII,EryAII,6-deoxyerythronolide-B synthase EryA3, modules 5 and 6, Antibody Fragment 1B2, Heavy Chain, Antibody Fragment 1B2, Light Chain (3 entities in total)
• Functional Keywords: polyketide synthase, antibody, biosynthetic protein
• Biological source: Saccharopolyspora erythraea; More
• Total number of polymer chains: 5
• Total formula weight: 611632.18

Authors

Cogan, D.P.,Soohoo, A.M.,Chen, M.,Brodsky, K.L.,Liu, Y.,Khosla, C. (deposition date: 2023-08-05, release date: 2024-08-07)

• Primary citation: Cogan, D.P.,Soohoo, A.M.,Chen, M.,Liu, Y.,Brodsky, K.L.,Khosla, C.; Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)