PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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1Y5X	tRNA-guanine Transglycosylase (TGT) in complex with 6-Amino-4-[2-(4-methoxyphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one 分子名称: 6-AMINO-4-[2-(4-METHOXYPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, Queuine tRNA-ribosyltransferase, ZINC ION 著者 Stengl, B, Meyer, E.A, Heine, A, Brenk, R, Diederich, F, Klebe, G. 登録日 2004-12-03 公開日 2005-12-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding J.Mol.Biol., 370, 2007
7XNY	High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Cheng, J, Beckmann, R. 登録日 2022-04-30 公開日 2023-04-05 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia. Cancer Discov, 13, 2023
4RD9	X-RAY STRUCTURE OF THE APO FORM OF THE AMYLOID PRECURSOR PROTEIN-LIKE PROTEIN 1 (APLP1) E2 DOMAIN 分子名称: Amyloid-like protein 1 著者 Dahms, S.O, Than, M.E. 登録日 2014-09-18 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes. Acta Crystallogr.,Sect.D, 71, 2015
4DHM	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
1JZ4	E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-DEOXY-GALACTOSYL-ENZYME INTERMEDIATE (Low Bis-Tris) 分子名称: 2-deoxy-alpha-D-galactopyranose, Beta-Galactosidase, DIMETHYL SULFOXIDE, ... 著者 Juers, D.H, Matthews, B.W. 登録日 2001-09-13 公開日 2001-12-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase Biochemistry, 40, 2001
4DHT	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 PROTEIN SIGMA, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2012-01-30 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
5A7A	Novel inter-subunit contacts in Barley Stripe Mosaic Virus revealed by cryo-EM 分子名称: BARLEY STRIPE MOSAIC VIRUS NARROW, RNA 著者 Clare, D.K, Pechnikova, E, Skurat, E, Makarov, V, Sokolova, O.S, Solovyev, A.G, V Orlova, E. 登録日 2015-07-03 公開日 2015-09-02 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Novel Inter-Subunit Contacts in Barley Stripe Mosaic Virus Revealed by Cryo-Electron Microscopy. Structure, 23, 2015
1DOB	THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID 著者 Gatti, D.L, Palfey, B.A, Lah, M.S, Entsch, B, Massey, V, Ballou, D.P, Ludwig, M.L. 登録日 1994-09-06 公開日 1994-11-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The mobile flavin of 4-OH benzoate hydroxylase. Science, 266, 1994
1PYX	GSK-3 Beta complexed with AMP-PNP 分子名称: Glycogen synthase kinase-3 beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M. 登録日 2003-07-09 公開日 2003-10-21 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors J.Mol.Biol., 333, 2003
2AJM	NMR structure of the in-plane membrane anchor domain [1-28] of the monotopic NonStructural Protein 5A (NS5A) from the Bovine Viral Diarrhea Virus (BVDV) 分子名称: Nonstructural protein 5A 著者 Sapay, N, Montserret, R, Chipot, C, Brass, V, Moradpour, D, Deleage, G, Penin, F. 登録日 2005-08-02 公開日 2005-08-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure and molecular dynamics of the in-plane membrane anchor of nonstructural protein 5A from bovine viral diarrhea virus. Biochemistry, 45, 2006
3IVK	Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment 分子名称: CADMIUM ION, CHLORIDE ION, Fab heavy chain, ... 著者 Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A. 登録日 2009-09-01 公開日 2010-03-02 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science, 326, 2009
2AJS	Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Antibody 7A1 FAB', GLYCEROL, ... 著者 Zhu, X, Wilson, I.A. 登録日 2005-08-02 公開日 2006-02-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure, 14, 2006
2AJZ	Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester 分子名称: 3-HYDROXY-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER, Antibody 7A1 Fab' 著者 Zhu, X, Wilson, I.A. 登録日 2005-08-02 公開日 2006-02-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure, 14, 2006
1YFD	Crystal structure of the Y122H mutant of ribonucleotide reductase R2 protein from E. coli 分子名称: MERCURY (II) ION, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 beta chain 著者 Kolberg, M, Logan, D.T, Bleifuss, G, Poetsch, S, Sjoeberg, B.M, Graeslund, A, Lubitz, W, Lassmann, G, Lendzian, F. 登録日 2004-12-31 公開日 2005-02-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies J.Biol.Chem., 280, 2005
5AAD	Aurora A kinase bound to an imidazopyridine inhibitor (7a) 分子名称: 7-(1-benzyl-1H-pyrazol-4-yl)-6-chloro-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine, AURORA KINASE A, SULFATE ION 著者 McIntyre, P.J, Kosmopoulou, M, Bayliss, R. 登録日 2015-07-24 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent. Bioorg.Med.Chem.Lett., 25, 2015
4KS6	Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 166-174 stretch 分子名称: 1,2-ETHANEDIOL, Botulinum neurotoxin A light chain, DI(HYDROXYETHYL)ETHER, ... 著者 Stura, E.A, Vera, L, Guitot, K, Dive, V. 登録日 2013-05-17 公開日 2014-06-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Covalent modification of the active site cysteine stresses Clostridium botulinum neurotoxin A To be Published
1Y6U	The Structure of the Excisionase (Xis) Protein from Conjugative Transposon Tn916 Provides Insights into the Regulation of Heterobivalent Tyrosine Recombinases 分子名称: Excisionase from transposon Tn916 著者 Abbani, M, Iwahara, M, Clubb, R.T. 登録日 2004-12-07 公開日 2005-03-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The structure of the excisionase (xis) protein from conjugative transposon tn916 provides insights into the regulation of heterobivalent tyrosine recombinases J.Mol.Biol., 347, 2005
1JFC	X-ray structure of nitric oxide reductase (cytochrome P450nor) in the ferrous CO state at atomic resolution 分子名称: CARBON MONOXIDE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shimizu, H, Adachi, S, Park, S.Y, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2001-06-20 公開日 2001-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 X-ray structure of nitric oxide reductase (cytochrome P450nor) at atomic resolution. Acta Crystallogr.,Sect.D, 58, 2002
5ABV	Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli 分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GH11071P 著者 Peter, D, Weichenrieder, O. 登録日 2015-08-09 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation Genes Dev., 29, 2015
4RCW	Crystal structure of human Slitrk1 分子名称: SLIT and NTRK-like protein 1 著者 Kim, H.M, Park, B.S, Kim, D, Lee, S.G. 登録日 2014-09-17 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1925 Å) 主引用文献 Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion. Nat Commun, 5, 2014
4K72	CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-VQD (ANSRVQDSII) 分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-VQD peptide 著者 Amacher, J.F, Madden, D.R. 登録日 2013-04-16 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses. Structure, 22, 2014
4INP	The crystal structure of Helicobacter pylori Ceue (HP1561) with Ni(II) bound 分子名称: ACETATE ION, Iron (III) ABC transporter, periplasmic iron-binding protein, ... 著者 Shaik, M.M, Cendron, L, Zanotti, G. 登録日 2013-01-05 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Helicobacter pylori periplasmic receptor CeuE (HP1561) modulates its nickel affinity via organic metallophores. Mol.Microbiol., 91, 2014
3V6P	Crystal structure of the DNA-binding domain of dHax3, a TAL effector 分子名称: dHax3 著者 Deng, D, Yan, C.Y, Pan, X.J, Wang, J.W, Shi, Y.G, Yan, N. 登録日 2011-12-20 公開日 2012-01-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors Science, 2012
5AKT	Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-4'-O- glucuronide 分子名称: Resveratrol-4'-O-glucuronide, SULFATE ION, TRANSTHYRETIN 著者 Florio, P, Folli, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R. 登録日 2015-03-05 公開日 2015-10-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites J.Biol.Chem., 290, 2015
1G76	X-RAY STRUCTURE OF ESCHERICHIA COLI PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 2.0 A RESOLUTION 分子名称: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Safo, M.K, Musayev, F.N, di Salvo, M.L, Schirch, V. 登録日 2000-11-09 公開日 2000-11-29 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution. J.Mol.Biol., 310, 2001

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