PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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3A5M	Crystal Structure of a Dictyostelium P109I Mg2+-Actin in Complex with Human Gelsolin Segment 1 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ... 著者 Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T. 登録日 2009-08-09 公開日 2010-10-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release Cell(Cambridge,Mass.), 143, 2010
7KCU	Joint neutron/X-ray structure of Oxyferrous Dehaloperoxidase B 分子名称: Dehaloperoxidase B, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Carey, L.M, Ghiladi, R.A, Meilleur, F, Myles, D. 登録日 2020-10-07 公開日 2021-10-13 最終更新日 2023-10-25 実験手法 NEUTRON DIFFRACTION (2.2 Å), X-RAY DIFFRACTION 主引用文献 Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature. Iucrj, 9, 2022
8TYN	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (tetramer model) 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-08-25 公開日 2024-06-12 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 59, 2024
8TPL	ATP-2 state of Bcs1 (unsymmetrized) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 著者 Zhan, J, Xia, D. 登録日 2023-08-04 公開日 2024-06-05 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
7PTJ	C54S mutant of choline-sulfatase from E. meliloti CECT4857 bound to HEPES 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, Choline sulfatase, ... 著者 Gavira, J.A, Martinez-Rodriguez, S. 登録日 2021-09-27 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding. Acta Crystallogr D Struct Biol, 78, 2022
5C6B	Crystal Structure of Prefusion-stabilized RSV F variant SC-TM 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Fusion glycoprotein F0,Fibritin, ... 著者 McLellan, J.S, Langedijk, J.P.M. 登録日 2015-06-22 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism. Nat Commun, 6, 2015
8T7U	ADP-bound Bcs1 (unsymmetrized) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1 著者 Zhan, J, Xia, D. 登録日 2023-06-21 公開日 2024-06-05 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
7Q46	Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of pericentriolar material 1 protein 分子名称: CITRIC ACID, E3 ubiquitin-protein ligase HERC2, Pericentriolar material 1 protein 著者 Demenge, A, Howard, E, Cousido-Siah, A, Mitschler, A, Podjarny, A, McEwen, A.G, Trave, G. 登録日 2021-10-29 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.46002531 Å) 主引用文献 Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of pericentriolar material 1 protein To Be Published
3A5W	Peroxiredoxin (wild type) from Aeropyrum pernix K1 (reduced form) 分子名称: Probable peroxiredoxin 著者 Nakamura, T, Kado, Y, Yamaguchi, T, Matsumura, H, Ishikawa, K, Inoue, T. 登録日 2009-08-12 公開日 2009-10-27 最終更新日 2014-01-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide J.Biochem., 147, 2010
8T5U	ATP-1 state of Bcs1 (C7 symmetrized) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 著者 Zhan, J, Xia, D. 登録日 2023-06-14 公開日 2024-06-05 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
2ZX8	alpha-L-fucosidase complexed with inhibitor, F10-2C-O 分子名称: Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide 著者 Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. 登録日 2008-12-19 公開日 2009-12-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49, 2010
8TI0	ATP-1 state of Bcs1 (unsymmetrized) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 著者 Zhan, J, Xia, D. 登録日 2023-07-18 公開日 2024-06-05 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.77 Å) 主引用文献 Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
7Q43	Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of dedicator of cytokinesis protein 10 分子名称: CITRIC ACID, Dedicator of cytokinesis protein 10 peptide, E3 ubiquitin-protein ligase HERC2 著者 Demenge, A, Howard, E, Cousido-Siah, A, Mitschler, A, Podjarny, A, McEwen, A.G, Trave, G. 登録日 2021-10-29 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.40002346 Å) 主引用文献 Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of dedicator of cytokinesis protein 10 To Be Published
3EZR	CDK-2 with indazole inhibitor 17 bound at its active site 分子名称: 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 著者 Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. 登録日 2008-10-23 公開日 2009-02-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor Bioorg.Med.Chem.Lett., 19, 2009
5EY6	CRYSTAL STRUCTURE OF GLUTATHIONE TRANSFERASE F2 FROM POPULUS TRICHOCARPA 分子名称: Phi class glutathione transferase GSTF2 著者 Didierjean, C, Rouhier, N, Pegeot, H, Gense, F. 登録日 2015-11-24 公開日 2016-12-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural plasticity among glutathione transferase Phi members: natural combination of catalytic residues confers dual biochemical activities. FEBS J., 284, 2017
5C7H	Crystal structure of aldo-keto reductase from Sinorhizobium meliloti 1021 in complex with NADPH 分子名称: Aldo-keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Gasiorowska, O.A, Shabalin, I.G, Handing, K.B, Seidel, R, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2015-06-24 公開日 2015-07-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of aldo-keto reductase from Sinorhizobium meliloti 1021 in complex with NADPH to be published
8TP1	ATP-2 state of Bcs1 (C7 symmetrized) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 著者 Zhan, J, Xia, D. 登録日 2023-08-04 公開日 2024-06-05 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate. Nat Commun, 15, 2024
2RQ6	Solution structure of the epsilon subunit of the F1-atpase from thermosynechococcus elongatus BP-1 分子名称: ATP synthase epsilon chain 著者 Yagi, H, Konno, H, Murakami-Fuse, T, Oroguchi, H, Akutsu, T, Ikeguchi, M, Hisabori, T. 登録日 2009-03-03 公開日 2010-01-12 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural and functional analysis of the intrinsic inhibitor subunit epsilon of F1-ATPase from photosynthetic organisms. Biochem.J., 425, 2010
7K1R	X-ray Structure of an Enterobacter GH43 Beta-Xylosidase: EcXyl43 F507A mutant 分子名称: Beta xylosidase GH43, CALCIUM ION, GLYCEROL 著者 Briganti, L, Capetti, C.C.M, Polikarpov, I. 登録日 2020-09-08 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 X-ray Structure of an Enterobacter GH43 Beta-Xylosidase: EcXyl43 F507A mutant To Be Published
7K57	Structure of apo VCP dodecamer generated from bacterially recombinant VCP/p97 分子名称: Transitional endoplasmic reticulum ATPase 著者 Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. 登録日 2020-09-16 公開日 2021-10-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
5EYO	The crystal structure of the Max bHLH domain in complex with 5-carboxyl cytosine DNA 分子名称: DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3'), Protein max 著者 Wang, D, Hashimoto, H, Zhang, X, Cheng, X. 登録日 2015-11-25 公開日 2016-12-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma. Nucleic Acids Res., 45, 2017
2DO7	Solution structure of the winged helix-turn-helix motif of human CUL-4B 分子名称: Cullin-4B 著者 Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-27 公開日 2007-04-17 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the winged helix-turn-helix motif of human CUL-4B To be Published
1NNY	Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 23 Using a Linked-Fragment Strategy 分子名称: 3-({5-[(N-ACETYL-3-{4-[(CARBOXYCARBONYL)(2-CARBOXYPHENYL)AMINO]-1-NAPHTHYL}-L-ALANYL)AMINO]PENTYL}OXY)-2-NAPHTHOIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 著者 Szczepankiewicz, B.G, Liu, G, Hajduk, P.J, Abad-Zapatero, C, Pei, Z, Xin, Z, Lubben, T, Trevillyan, J.M, Stashko, M.A, Ballaron, S.J, Liang, H, Huang, F, Hutchins, C.W, Fesik, S.W, Jirousek, M.R. 登録日 2003-01-14 公開日 2003-04-08 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Using a Linked-Fragment Strategy J.Am.Chem.Soc., 125, 2003
3F17	Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-(2-nitroso-2-oxoethyl)biphenyl-4-sulfonamide 分子名称: CALCIUM ION, Macrophage metalloelastase, N-oxidanyl-2-[(4-phenylphenyl)sulfonylamino]ethanamide, ... 著者 Calderone, V. 登録日 2008-10-27 公開日 2008-11-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J.Am.Chem.Soc., 129, 2007
8TYM	Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-08-25 公開日 2024-06-12 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 59, 2024

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