PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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2HSY	Solution structure of Thioredoxin 2 from Saccharomyces cerevisiae 分子名称: Thioredoxin II 著者 Amorim, G.C, Valente, A.P, Almeida, F.C.L. 登録日 2006-07-24 公開日 2007-03-20 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR solution structure of the reduced form of thioredoxin 2 from Saccharomyces cerevisiae J.Biomol.Nmr, 38, 2007
2HOT	Phage selected homeodomain bound to modified DNA 分子名称: 3-PROP-2-YN-1-YL-1,3-OXAZOLIDIN-2-ONE, 5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*CP*CP*GP*GP*A)-3', ... 著者 Feldman, M.E, Simon, M.D, Shokat, K.M. 登録日 2006-07-16 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structure and properties of a re-engineered homeodomain protein-DNA interface. Acs Chem.Biol., 1, 2006
2HS6	Crystal structure of the E291K mutant of 12-oxophytodienoate reductase 3 (OPR3) from tomato 分子名称: 12-oxophytodienoate reductase 3, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE 著者 Breithaupt, C, Clausen, T, Huber, R. 登録日 2006-07-21 公開日 2006-09-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of 12-oxophytodienoate reductase 3 from tomato: Self-inhibition by dimerization. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HOC	Crystal structure of the human carbonic anhydrase II in complex with the 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide inhibitor 分子名称: 5-{[(4-AMINO-3-CHLORO-5-FLUOROPHENYL)SULFONYL]AMINO}-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, GLYCEROL, ... 著者 Menchise, V, Di Fiore, A, De Simone, G. 登録日 2006-07-14 公開日 2006-10-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide to human isoform II. Bioorg.Med.Chem.Lett., 16, 2006
2HPU	Solution NMR structure of the apo-NosL protein from Achromobacter cycloclastes 分子名称: NosL protein 著者 Taubner, L.M, McGuirl, M.A, Dooley, D.M, Copie, V. 登録日 2006-07-17 公開日 2006-10-24 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural Studies of Apo Nosl, an Accessory Protein of the Nitrous Oxide Reductase System: Insights from Structural Homology with MerB, a Mercury Resistance Protein. Biochemistry, 45, 2006
2HS8	Crystal structure of the Y364F mutant of 12-oxophytodienoate reductase 3 from tomato 分子名称: 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE 著者 Breithaupt, C, Clausen, T, Huber, R. 登録日 2006-07-21 公開日 2006-09-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of 12-oxophytodienoate reductase 3 from tomato: Self-inhibition by dimerization. Proc.Natl.Acad.Sci.Usa, 103, 2006
2HU9	X-ray structure of the Archaeoglobus fulgidus CopZ N-terminal Domain 分子名称: ACETIC ACID, FE2/S2 (INORGANIC) CLUSTER, Mercuric transport protein periplasmic component, ... 著者 Sazinsky, M.H, LeMoine, B, Arguello, J.M, Rosenzweig, A.C. 登録日 2006-07-26 公開日 2007-07-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Characterization and structure of a Zn2+ and [2Fe-2S]-containing copper chaperone from Archaeoglobus fulgidus. J.Biol.Chem., 282, 2007
2HV5	Human Aldose Reductase complexed with inhibitor zopolrestat after three days soaking (3days_soaked_3) 分子名称: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Steuber, H, Heine, A, Klebe, G. 登録日 2006-07-27 公開日 2006-10-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J.Mol.Biol., 363, 2006
2HVN	Human Aldose Reductase-zopolrestat complex obtained by cocrystallisation after one day (1day_cocryst) 分子名称: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Steuber, H, Heine, A, Klebe, G. 登録日 2006-07-29 公開日 2006-10-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J.Mol.Biol., 363, 2006
2HVO	Human Aldose Reductase-zopolrestat complex obtained by cocrystallisation (10days_cocryst) 分子名称: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Steuber, H, Heine, A, Klebe, G. 登録日 2006-07-29 公開日 2006-10-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J.Mol.Biol., 363, 2006
2I17	Human aldose reductase in complex with NADP+ and the inhibitor IDD594 at temperature of 60K 分子名称: Aldose reductase, CITRIC ACID, IDD594, ... 著者 Petrova, T, Ginell, S, Mitshler, A, Hasemann, I, Schneider, T, Cousido, A, Lunin, V.Y, Joachimiak, A, Podjarny, A. 登録日 2006-08-13 公開日 2006-08-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (0.81 Å) 主引用文献 Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat. Acta Crystallogr.,Sect.D, 62, 2006
2I67	Structural Basis for the Mechanistic Understanding Human CD38 Controlled Multiple Catalysis 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribosyl cyclase 1 著者 Liu, Q, Kriksunov, I.A, Graeff, R, Munshi, C, Lee, H.C, Hao, Q. 登録日 2006-08-28 公開日 2006-09-05 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis. J.Biol.Chem., 281, 2006
2HXT	Crystal structure of L-Fuconate Dehydratase from Xanthomonas campestris liganded with Mg++ and D-erythronohydroxamate 分子名称: (2R,3R)-N,2,3,4-TETRAHYDROXYBUTANAMIDE, L-fuconate dehydratase, MAGNESIUM ION 著者 Fedorov, A.A, Fedorov, E.V, Yew, W.S, Rakus, J.F, Gerlt, J.A, Almo, S.C. 登録日 2006-08-03 公開日 2006-12-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris. Biochemistry, 45, 2006
2I0M	Crystal structure of the phosphate transport system regulatory protein PhoU from Streptococcus pneumoniae 分子名称: Phosphate transport system protein phoU, ZINC ION 著者 Zhang, R, Li, H, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2006-08-10 公開日 2006-09-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the phosphate transport system regulatory protein PhoU from Streptococcus pneumoniae To be Published, 2006
2I16	Human aldose reductase in complex with NADP+ and the inhibitor IDD594 at temperature of 15K 分子名称: Aldose reductase, CITRIC ACID, IDD594, ... 著者 Petrova, T, Ginell, S, Mitshler, A, Hasemann, I, Schneider, T, Cousido, A, Lunin, V.Y, Joachimiak, A, Podjarny, A. 登録日 2006-08-13 公開日 2006-08-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (0.81 Å) 主引用文献 Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat. Acta Crystallogr.,Sect.D, 62, 2006
2I3E	Solution structure of catalytic domain of goldfish RICH protein 分子名称: G-RICH 著者 Denisov, A.Y, Kozlov, G, Gehring, K. 登録日 2006-08-18 公開日 2007-03-06 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the catalytic domain of RICH protein from goldfish. Febs J., 274, 2007
2HYG	The Structure of apo-MntR from Bacillus subtilis, Native Form 分子名称: Transcriptional regulator mntR 著者 Glasfeld, A, Kliegman, J.I. 登録日 2006-08-06 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state. J.Mol.Biol., 365, 2007
7P47	Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic 分子名称: E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ... 著者 Lascorz, J, Varejao, N, Reverter, D. 登録日 2021-07-09 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.314 Å) 主引用文献 Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs. Nat Commun, 12, 2021
4PHA	Structure of human DNA polymerase beta complexed with A in the template base paired with incoming non-hydrolyzable CTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.C, Lee, S. 登録日 2014-05-05 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase beta. Nucleic Acids Res., 42, 2015
6BLP	Pol II elongation complex with an abasic lesion at i+1 position, soaking AMPCPP 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(P*AP*(3DR)P*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, W, Wang, D. 登録日 2017-11-11 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.203 Å) 主引用文献 Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7P5K	Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 interaction 分子名称: 5-cyclopropyl-1-[3-[2-fluoranyl-3-[(2~{R})-2-propylpiperidin-1-yl]carbonyl-phenyl]phenyl]pyrazole-4-carboxylic acid, CHLORIDE ION, Kelch-like ECH-associated protein 1 著者 Davies, T.G. 登録日 2021-07-14 公開日 2021-11-17 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction. J.Med.Chem., 64, 2021
4Z0Q	Carbonic anhydrase inhibitors: Design and synthesis of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hCA VII, hCA IX, and hCA XIV) 分子名称: 4-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)benzenesulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Brynda, J, Pospisilova, K, Rezacova, P, Pachl, P. 登録日 2015-03-26 公開日 2015-08-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. Eur.J.Med.Chem., 102, 2015
6BOR	Human APE1 substrate complex with an G/G mismatch adjacent the THF 分子名称: 1,2-ETHANEDIOL, 21-mer DNA, CHLORIDE ION, ... 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
6TX4	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH 2-PYRIDONE 分子名称: 1~{H}-pyridin-2-one, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase FKBP5, ... 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-13 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
4Z1J	Carbonic anhydrase inhibitors: Design and synthesis of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hCA VII, hCA IX, and hCA XIV) 分子名称: 4-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)benzenesulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Brynda, J, Pospisilova, K, Rezacova, P, Pachl, P. 登録日 2015-03-27 公開日 2015-08-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. Eur.J.Med.Chem., 102, 2015

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