4J2E
| RB69 DNA Polymerase L415M Ternary Complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*G)-3'), ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2013-02-04 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res., 41, 2013
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7CXY
| Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (zinc-bound form) | 分子名称: | Carbonic anhydrase, ZINC ION | 著者 | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | 登録日 | 2020-09-02 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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7CXX
| Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (disulfide-bonded form) | 分子名称: | ACETATE ION, Carbonic anhydrase, SULFATE ION | 著者 | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | 登録日 | 2020-09-02 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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7CXW
| Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (C116 flipped form) | 分子名称: | ACETATE ION, Carbonic anhydrase | 著者 | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | 登録日 | 2020-09-02 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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3JQ4
| The structure of the complex of the large ribosomal subunit from D. Radiodurans with the antibiotic lankacidin | 分子名称: | 23S ribosomal RNA, 5S ribosomal RNA, N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide | 著者 | Auerbach-Nevo, T, Mermershtain, I, Davidovich, C, Bashan, A, Rozenberg, H, Yonath, A. | 登録日 | 2009-09-06 | 公開日 | 2010-09-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | 主引用文献 | The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics Proc.Natl.Acad.Sci.USA, 107, 2010
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4NAO
| Crystal structure of EasH | 分子名称: | 2-OXOGLUTARIC ACID, FE (II) ION, HEXAETHYLENE GLYCOL, ... | 著者 | Janke, R, Havemann, J, Vogel, D, Keller, U, Loll, B. | 登録日 | 2013-10-22 | 公開日 | 2014-01-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | 主引用文献 | Cyclolization of d-lysergic Acid alkaloid peptides. Chem.Biol., 21, 2014
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2PL7
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1MG3
| MUTATION OF ALPHA PHE55 OF METHYLAMINE DEHYDROGENASE ALTERS THE REORGANIZATION ENERGY AND ELECTRONIC COUPLING FOR ITS ELECTRON TRANSFER REACTION WITH AMICYANIN | 分子名称: | Amicyanin, COPPER (II) ION, CYTOCHROME C-L, ... | 著者 | Sun, D, Chen, Z.W, Mathews, F.S, Davidson, V.L. | 登録日 | 2002-08-14 | 公開日 | 2002-12-11 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | MUTATION OF ALPHA PHE55 OF METHYLAMINE DEHYDROGENASE ALTERS THE REORGANIZATION ENERGY AND ELECTRONIC COUPLING FOR ITS ELECTRON TRANSFER REACTION WITH AMICYANIN Biochemistry, 41, 2002
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1PKL
| THE STRUCTURE OF LEISHMANIA PYRUVATE KINASE | 分子名称: | PROTEIN (PYRUVATE KINASE), SULFATE ION | 著者 | Rigden, D.J, Phillips, S.E.V, Michels, P.A.M, Fothergill-Gilmore, L.A. | 登録日 | 1998-09-15 | 公開日 | 1998-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The structure of pyruvate kinase from Leishmania mexicana reveals details of the allosteric transition and unusual effector specificity. J.Mol.Biol., 291, 1999
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4BTZ
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1QT9
| OXIDIZED [2FE-2S] FERREDOXIN FROM ANABAENA PCC7119 | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN I | 著者 | Morales, R, Chron, M.-H, Hudry-Clergeon, G, Petillot, Y, Norager, S, Medina, M, Frey, M. | 登録日 | 1999-07-01 | 公開日 | 1999-12-02 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Refined X-ray structures of the oxidized, at 1.3 A, and reduced, at 1.17 A, [2Fe-2S] ferredoxin from the cyanobacterium Anabaena PCC7119 show redox-linked conformational changes. Biochemistry, 38, 1999
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8CE0
| N-terminal domain of human apolipoprotein E | 分子名称: | GLYCEROL, Maltodextrin-binding protein,Apolipoprotein E | 著者 | Marek, M, Nemergut, M. | 登録日 | 2023-02-01 | 公開日 | 2023-07-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. Mol Neurodegener, 18, 2023
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8CDY
| N-terminal domain of human apolipoprotein E | 分子名称: | Maltodextrin-binding protein,Apolipoprotein E | 著者 | Marek, M, Nemergut, M. | 登録日 | 2023-02-01 | 公開日 | 2023-07-19 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. Mol Neurodegener, 18, 2023
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4M9W
| Crystal Structure of Ara h 8 with MES bound | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ara h 8 allergen, SODIUM ION | 著者 | Offermann, L.R, Hurlburt, B.K, Majorek, K.A, McBride, J.K, Maleki, S.J, Chruszcz, M. | 登録日 | 2013-08-15 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure and Function of the Peanut Panallergen Ara h 8. J.Biol.Chem., 288, 2013
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4MA6
| Crystal structure of Ara h 8 with Epicatechin bound | 分子名称: | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol, Ara h 8 allergen, SODIUM ION | 著者 | Offermann, L.R, Hurlburt, B.K, Majorek, K.A, McBride, J.K, Maleki, S.J, Chruszcz, M. | 登録日 | 2013-08-15 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and Function of the Peanut Panallergen Ara h 8. J.Biol.Chem., 288, 2013
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5JW6
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2R4R
| Crystal structure of the human beta2 adrenoceptor | 分子名称: | Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ... | 著者 | Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K. | 登録日 | 2007-08-31 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature, 450, 2007
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2R82
| Pyruvate phosphate dikinase (PPDK) triple mutant R219E/E271R/S262D adapts a second conformational state | 分子名称: | Pyruvate, phosphate dikinase, SULFATE ION | 著者 | Lim, K, Read, R.J, Chen, C.C, Herzberg, O. | 登録日 | 2007-09-10 | 公開日 | 2008-01-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry, 46, 2007
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8K4Q
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2XQ2
| Structure of the K294A mutant of vSGLT | 分子名称: | DI(HYDROXYETHYL)ETHER, SODIUM/GLUCOSE COTRANSPORTER | 著者 | Watanabe, A, Choe, S, Chaptal, V, Rosenberg, J.M, Wright, E.M, Grabe, M, Abramson, J. | 登録日 | 2010-09-01 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | The Mechanism of Sodium and Substrate Release from the Binding Pocket of Vsglt Nature, 468, 2010
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8CZ7
| Crystal structure of SARS-CoV-2 Mpro with compound C2 | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-(4-methoxyphenyl)acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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8CYZ
| Crystal structure of SARS-CoV-2 Mpro with compound C4 | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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8CYU
| Crystal structure of SARS-CoV-2 Mpro with compound C5 | 分子名称: | 3C-like proteinase, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(isoquinolin-4-yl)acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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8CZ4
| Crystal structure of SARS-CoV-2 Mpro with compound C3 | 分子名称: | 3C-like proteinase, N-(4-tert-butylphenyl)-N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)acetamide | 著者 | Worrall, L.J, Lee, J, Strynadka, N.C.J. | 登録日 | 2022-05-24 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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4MAP
| Crystal structure of Ara h 8 purified with heating | 分子名称: | Ara h 8 allergen, SODIUM ION | 著者 | Offermann, L.R, Hurlburt, B.K, Majorek, K.A, McBride, J.K, Maleki, S.J, Chruszcz, M. | 登録日 | 2013-08-16 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and Function of the Peanut Panallergen Ara h 8. J.Biol.Chem., 288, 2013
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