PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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4DK7	Crystal structure of LXR ligand binding domain in complex with full agonist 1 分子名称: ACETATE ION, CALCIUM ION, N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methylbenzenesulfonamide, ... 著者 Piper, D.E, Xu, H. 登録日 2012-02-03 公開日 2012-03-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery of a new binding mode for a series of liver X receptor agonists. Bioorg.Med.Chem.Lett., 22, 2012
6KX9	Crystal structure of 8-mer peptide from avian influenza H5N1 virus in complex with BF2*1501 分子名称: 8-pepide (ARG-ARG-ALA-LEU-ARG-GLU-GLY-TYR), Beta-2-microglobulin, MHC class I 著者 Xiao, L, Zhang, L. 登録日 2019-09-10 公開日 2020-04-01 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 Structures of the MHC-I molecule BF2*1501 disclose the preferred presentation of an H5N1 virus-derived epitope. J.Biol.Chem., 295, 2020
2D21	NMR Structure of stereo-array isotope labelled (SAIL) maltodextrin-binding protein (MBP) 分子名称: Maltose-binding periplasmic protein 著者 Kainosho, M, Torizawa, T, Iwashita, Y, Terauchi, T, Ono, A.M, Guntert, P. 登録日 2005-09-02 公開日 2006-03-07 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Optimal isotope labelling for NMR protein structure determinations. Nature, 440, 2006
1K0J	Pseudomonas aeruginosa phbh R220Q in complex with NADPH and free of p-OHB 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, P-HYDROXYBENZOATE HYDROXYLASE, ... 著者 Wang, J, Ortiz-Maldonado, M, Entsch, B, Ballou, D, Gatti, D.L. 登録日 2001-09-19 公開日 2002-02-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase. Proc.Natl.Acad.Sci.USA, 99, 2002
3H5E	LeuD_1-156 small subunit of isopropylmalate isomerase (Rv2987c) from mycobacterium tuberculosis 分子名称: 3-isopropylmalate dehydratase small subunit 著者 Manikandan, K, Geerlof, A, Weiss, M.S. 登録日 2009-04-22 公開日 2010-04-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural studies on the enzyme complex isopropylmalate isomerase (LeuCD) from Mycobacterium tuberculosis Proteins, 79, 2011
3UKA	CRYSTAL STRUCTURE OF UDP-galactopyranose mutase from Aspergillus fumigatus 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, UDP-galactopyranose mutase 著者 Van Straaten, K.E, Sanders, D.A.R. 登録日 2011-11-09 公開日 2012-02-22 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus. J.Biol.Chem., 287, 2012
2A3I	Structural and Biochemical Mechanisms for the Specificity of Hormone Binding and Coactivator Assembly by Mineralocorticoid Receptor 分子名称: CORTICOSTERONE, Mineralocorticoid receptor, Nuclear receptor coactivator 1, ... 著者 Li, Y, Suino, K, Daugherty, J, Xu, H.E. 登録日 2005-06-24 公開日 2005-07-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor Mol.Cell, 19, 2005
2AAQ	Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI 分子名称: 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Urig, S, Fritz-Wolf, K, Reau, R, Herold-Mende, C, Toth, K, Davioud-Charvet, E, Becker, K. 登録日 2005-07-14 公開日 2006-04-04 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Undressing of Phosphine Gold(I) Complexes as Irreversible Inhibitors of Human Disulfide Reductases. Angew.Chem.Int.Ed.Engl., 45, 2006
1JE4	Solution structure of the monomeric variant of the chemokine MIP-1beta 分子名称: macrophage inflammatory protein 1-beta 著者 Kim, S, Jao, S, Laurence, J.S, LiWang, P.J. 登録日 2001-06-15 公開日 2001-10-03 最終更新日 2024-11-13 実験手法 SOLUTION NMR 主引用文献 Structural comparison of monomeric variants of the chemokine MIP-1beta having differing ability to bind the receptor CCR5. Biochemistry, 40, 2001
2ACQ	AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE 分子名称: 6-O-phosphono-alpha-D-glucopyranose, ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. 登録日 1994-04-15 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate. Biochemistry, 33, 1994
4GZZ	Crystal structures of bacterial RNA Polymerase paused elongation complexes 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A. 登録日 2012-09-06 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.2927 Å) 主引用文献 Structural basis of transcriptional pausing in bacteria. Cell(Cambridge,Mass.), 152, 2013
3NP2	Crystal Structure of Pd(allyl)/apo-E45C/C48A-rHLFr 分子名称: 1,2-ETHANEDIOL, CADMIUM ION, Ferritin light chain, ... 著者 Wang, Z, Ueno, T, Abe, S, Takezawa, Y, Aoyagi, H, Hikage, T, Watanabe, Y, Kitagawa, S. 登録日 2010-06-27 公開日 2010-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Definite coordination arrangement of organometallic palladium complexes accumulated on the designed interior surface of apo-ferritin. Chem.Commun.(Camb.), 47, 2011
6KRQ	Peroxiredoxin from Aeropyrum pernix K1 (ApPrx) 0Cys F80A mutant 分子名称: CITRIC ACID, Peroxiredoxin 著者 Himiyama, T, Nakamura, T. 登録日 2019-08-22 公開日 2020-07-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation. Protein Sci., 29, 2020
1JN3	FIDELITY PROPERTIES AND STRUCTURE OF M282L MUTATOR MUTANT OF DNA POLYMERASE: SUBTLE STRUCTURAL CHANGES INFLUENCE THE MECHANISM OF NUCLEOTIDE DISCRIMINATION 分子名称: DNA POLYMERASE BETA 著者 Conn, D.A, Sweasy, J.B, Jaeger, J. 登録日 2001-07-22 公開日 2001-08-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability Biochemistry, 40, 2001
4JCT	ClpP2 from Listeria monocytogenes 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Zeiler, E, List, A, Alte, F, Gersch, M, Wachtel, R, Groll, M, Sieber, S. 登録日 2013-02-22 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad. Proc.Natl.Acad.Sci.USA, 110, 2013
4J7A	Crystal Structure of Est25 - a Bacterial Homolog of Hormone-Sensitive Lipase from a Metagenomic Library 分子名称: Esterase 著者 Ngo, T.D, Ryu, B.H, Ju, H.S, Jang, E.J, Park, K.S, Joo, S.B, Kim, K.K, Kim, D.H. 登録日 2013-02-13 公開日 2014-01-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.492 Å) 主引用文献 Structural and functional analyses of a bacterial homologue of hormone-sensitive lipase from a metagenomic library Acta Crystallogr.,Sect.D, 69, 2014
4J90	Square-shaped octameric structure of KtrA with ATP bound 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A 著者 Vieira-Pires, R.S, Morais-Cabral, J.H. 登録日 2013-02-15 公開日 2013-04-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.24 Å) 主引用文献 The structure of the KtrAB potassium transporter Nature, 496, 2013
3GTM	Co-complex of Backtracked RNA polymerase II with TFIIS 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
6LIN	Crystal structure of human PDK2 complexed with GM10030 分子名称: 4-[[[4-[3,5-bis(fluoranyl)-4-(4-oxidanyl-4-oxidanylidene-butoxy)phenyl]-5-[5-chloranyl-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-3-yl]carbonylamino]methyl]benzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Kang, J, Kim, J. 登録日 2019-12-12 公開日 2020-09-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds. Biochem.Biophys.Res.Commun., 527, 2020
1ROZ	Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form 分子名称: Deoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Umland, T.C, Wolff, E.C, Park, M.-H, Davies, D.R. 登録日 2003-12-02 公開日 2004-07-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 A New Crystal Structure of Deoxyhypusine Synthase Reveals the Configuration of the Active Enzyme and of an Enzyme-NAD-Inhibitor Ternary Complex J.Biol.Chem., 279, 2004
2H15	Carbonic anhydrase inhibitors: Clashing with Ala65 as a means of designing isozyme-selective inhibitors that show low affinity for the ubiquitous isozyme II 分子名称: Carbonic anhydrase 2, MERCURY (II) ION, N-{[(3AS,5AR,8AR,8BS)-2,2,7,7-TETRAMETHYLTETRAHYDRO-3AH-BIS[1,3]DIOXOLO[4,5-B:4',5'-D]PYRAN-3A-YL]METHYL}SULFAMIDE, ... 著者 Winum, J.Y, Temperini, C, Ciattini, S, Scozzafava, A, Supuran, C.T. 登録日 2006-05-16 公開日 2007-03-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue. J.Med.Chem., 49, 2006
3W0D	Structure of elastase inhibitor AFUEI (cyrstal form I) 分子名称: Elastase inhibitor AFUEI 著者 Imada, K, Sakuma, M, Okumura, Y, Ogawa, K, Nikai, T, Homma, M. 登録日 2012-10-29 公開日 2013-05-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray Structure Analysis and Characterization of AFUEI, an Elastase Inhibitor from Aspergillus fumigatus J.Biol.Chem., 288, 2013
4HFM	X-ray Crystal Structure of a NADP(H)-bound Double Bond Reductase from Nicotiana tabacum 分子名称: Allyl alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Toogood, H.S, Scrutton, N.S. 登録日 2012-10-05 公開日 2013-01-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase fromNicotiana tabacum. ACS Catal, 3, 2013
2GLX	Crystal Structure Analysis of bacterial 1,5-AF Reductase 分子名称: 1,5-anhydro-D-fructose reductase, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Dambe, T.R, Scheidig, A.J. 登録日 2006-04-05 公開日 2006-08-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of NADP(H)-Dependent 1,5-Anhydro-d-fructose Reductase from Sinorhizobium morelense at 2.2 A Resolution: Construction of a NADH-Accepting Mutant and Its Application in Rare Sugar Synthesis Biochemistry, 45, 2006
6LJS	Crystal structure of human FABP4 in complex with a novel inhibitor 分子名称: 1,2-ETHANEDIOL, 2-[(2-phenylphenyl)amino]benzoic acid, Fatty acid-binding protein, ... 著者 Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020

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