1ROZ
Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form
Summary for 1ROZ
| Entry DOI | 10.2210/pdb1roz/pdb |
| Related | 1DHS 1RLZ |
| Descriptor | Deoxyhypusine synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total) |
| Functional Keywords | rossmann fold, nad cofactor, deoxyhypusine, hypusine, spermidine, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 83351.72 |
| Authors | Umland, T.C.,Wolff, E.C.,Park, M.-H.,Davies, D.R. (deposition date: 2003-12-02, release date: 2004-07-13, Last modification date: 2023-08-23) |
| Primary citation | Umland, T.C.,Wolff, E.C.,Park, M.-H.,Davies, D.R. A New Crystal Structure of Deoxyhypusine Synthase Reveals the Configuration of the Active Enzyme and of an Enzyme-NAD-Inhibitor Ternary Complex J.Biol.Chem., 279:28697-28705, 2004 Cited by PubMed: 15100216DOI: 10.1074/jbc.M404095200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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