PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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3GST	STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE 分子名称: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, GLUTATHIONE S-TRANSFERASE, SULFATE ION 著者 Ji, X, Ammon, H.L, Armstrong, R.N, Gilliland, G.L. 登録日 1993-06-07 公開日 1993-10-31 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene. Biochemistry, 33, 1994
3GTL	Backtracked RNA polymerase II complex with 13mer with G<>U mismatch 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
1K5A	Crystal structure of human angiogenin double variant I119A/F120A 分子名称: Angiogenin 著者 Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. 登録日 2001-10-10 公開日 2002-03-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Biochemistry, 41, 2002
3MZC	Human carbonic ahydrase II in complex with a benzenesulfonamide inhibitor 分子名称: 4-[(cyclopentylcarbamoyl)amino]benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Avvaru, B.S, Wagner, J, Robbins, A.H, Mckenna, R. 登録日 2010-05-12 公開日 2011-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.498 Å) 主引用文献 Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency. Chem.Commun.(Camb.), 46, 2010
5BKB	Crystal structure of AAD-1 in complex with (R)-dichlorprop, Mn(II), and 2-oxoglutarate 分子名称: (2R)-2-(2,4-dichlorophenoxy)propanoic acid, (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, ... 著者 Chekan, J.R, Nair, S.K. 登録日 2019-06-02 公開日 2019-06-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.582 Å) 主引用文献 Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
3WK8	Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 分子名称: 6-(trifluoromethyl)-1,3-benzothiazol-2-amine, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... 著者 Amano, Y, Yamaguchi, T, Tanabe, E. 登録日 2013-10-17 公開日 2014-04-16 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography. Bioorg.Med.Chem., 22, 2014
1QQ5	STRUCTURE OF L-2-HALOACID DEHALOGENASE FROM XANTHOBACTER AUTOTROPHICUS 分子名称: FORMIC ACID, PROTEIN (L-2-HALOACID DEHALOGENASE) 著者 Ridder, I.S, Rozeboom, H.J, Kalk, K.H, Dijkstra, B.W. 登録日 1999-06-10 公開日 1999-10-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Crystal structures of intermediates in the dehalogenation of haloalkanoates by L-2-haloacid dehalogenase. J.Biol.Chem., 274, 1999
3GXX	Structure of the SH2 domain of the Candida glabrata transcription elongation factor Spt6, crystal form B 分子名称: Transcription elongation factor SPT6 著者 Dengl, S, Mayer, A, Sun, M, Cramer, P. 登録日 2009-04-03 公開日 2009-05-26 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and in vivo requirement of the yeast Spt6 SH2 domain J.Mol.Biol., 389, 2009
2GNJ	PKA three fold mutant model of Rho-kinase with Y-27632 分子名称: (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... 著者 Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. 登録日 2006-04-10 公開日 2006-05-23 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
1ZW8	Solution structure of a ZAP1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae 分子名称: ZINC ION, Zinc-responsive transcriptional regulator ZAP1 著者 Wang, Z, Feng, L.S, Venkataraman, K, Matskevich, V.A, Parasuram, P, Laity, J.H. 登録日 2005-06-03 公開日 2006-01-10 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of a Zap1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae. J.Mol.Biol., 357, 2006
3WKA	Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor 分子名称: 6-amino-1-methyl-5-(piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... 著者 Amano, Y, Yamaguchi, T, Tanabe, E. 登録日 2013-10-18 公開日 2014-04-16 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography. Bioorg.Med.Chem., 22, 2014
2HCT	Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine NAAPD synthesis and hydrolysis activities 分子名称: ADP-ribosyl cyclase 1, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE 著者 Liu, Q, Kriksunov, I.A, Hao, Q, Graeff, R, Lee, H.C. 登録日 2006-06-18 公開日 2006-08-22 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities. J.Biol.Chem., 281, 2006
1QB8	CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI 分子名称: ADENINE PHOSPHORIBOSYLTRANSFERASE, ADENOSINE MONOPHOSPHATE, CITRIC ACID, ... 著者 Hill, C.P, Phillips, C.L. 登録日 1999-04-30 公開日 1999-07-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani. EMBO J., 18, 1999
4J03	Crystal structure of human soluble epoxide hydrolase complexed with fulvestrant 分子名称: (7beta,9beta,13alpha,17beta)-7-{9-[(R)-(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... 著者 Morisseau, C, Pakhomova, S, Hwang, S.H, Newcomer, M.E, Hammock, B.D. 登録日 2013-01-30 公開日 2013-06-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg.Med.Chem.Lett., 23, 2013
2GNH	PKA five fold mutant model of Rho-kinase with H1152P 分子名称: (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... 著者 Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. 登録日 2006-04-10 公開日 2006-05-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
5BNI	Porcine CD38 complexed with complexed with a covalent intermediate, ribo-F-ribose-5'-phosphate 分子名称: Uncharacterized protein, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4S)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 著者 Ting, K.Y, Leung, C.F.P, Graeff, R.M, Lee, H.C, Hao, Q, Kotaka, M. 登録日 2015-05-26 公開日 2016-05-25 最終更新日 2025-04-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity. Protein Sci., 25, 2016
6KH0	Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes 分子名称: FE (III) ION, Ferritin 著者 Gu, C, Zhang, T, Zhao, G. 登録日 2019-07-12 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes. Chemistry, 26, 2020
1K93	Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin 分子名称: CALCIUM ION, CALMODULIN, CALMODULIN-SENSITIVE ADENYLATE CYCLASE, ... 著者 Drum, C.L, Yan, S.-Z, Bard, J, Shen, Y.-Q, Lu, D, Soelaiman, S, Grabarek, Z, Bohm, A, Tang, W.-J. 登録日 2001-10-26 公開日 2002-01-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. Nature, 415, 2002
2H74	Crystal Structure of Thioredoxin Mutant D2E in Hexagonal (p61) Space Group 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin 著者 Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2006-06-01 公開日 2007-05-15 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Thioredoxin Mutant D2E in Hexagonal (p61) Space Group To be Published
2CBD	STRUCTURE OF NATIVE AND APO CARBONIC ANHYDRASE II AND SOME OF ITS ANION-LIGAND COMPLEXES 分子名称: CARBONIC ANHYDRASE II, SULFITE ION, ZINC ION 著者 Hakansson, K, Carlsson, M, Svensson, L.A, Liljas, A. 登録日 1992-06-01 公開日 1993-10-31 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes. J.Mol.Biol., 227, 1992
2H9G	Crystal structure of phage derived Fab BdF1 with human Death Receptor 5 (DR5) 分子名称: Fab BdF1, heavy chain, light chain, ... 著者 Hymowitz, S.G, Compaan, D.M. 登録日 2006-06-09 公開日 2006-08-08 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists. J.Mol.Biol., 361, 2006
3W5Y	MamM-CTD 分子名称: Magnetosome protein MamM, SULFATE ION 著者 Zeytuni, N, Davidov, G, Zarivach, R. 登録日 2013-02-10 公開日 2014-04-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Cation diffusion facilitators transport initiation and regulation is mediated by cation induced conformational changes of the cytoplasmic domain Plos One, 9, 2014
3W65	MamM-CTD D249A and H264A 分子名称: Magnetosome protein MamM, SULFATE ION 著者 Zeytuni, N, Davidov, G, Zarivach, R. 登録日 2013-02-10 公開日 2014-04-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Cation diffusion facilitators transport initiation and regulation is mediated by cation induced conformational changes of the cytoplasmic domain Plos One, 9, 2014
1QI1	Ternary Complex of an NADP Dependent Aldehyde Dehydrogenase 分子名称: GLYCERALDEHYDE-3-PHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (NADP-DEPENDENT NONPHOSPHORYLATING GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), ... 著者 Cobessi, D, Tete-Favier, F, Marchal, S, Branlant, G, Aubry, A. 登録日 1999-06-02 公開日 2001-01-10 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans. J.Mol.Biol., 300, 2000
3N3J	Crystal structure of human carbonic anhydrase II in complex with a benzenesulfonamide inhibitor 分子名称: 4-({[2-(1-methylethyl)phenyl]carbamoyl}amino)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Avvaru, B.S, Wagner, J, Robbins, A.H, McKenna, R. 登録日 2010-05-20 公開日 2011-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency. Chem.Commun.(Camb.), 46, 2010

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