Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4MWB
DownloadVisualize
BU of 4mwb by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[(2,5-dichlorothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1509)
分子名称: 1-(3-{[(2,5-dichlorothiophen-3-yl)methyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2013-09-24
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
7B9M
DownloadVisualize
BU of 7b9m by Molmil
Cys-45-tethered stabilizer 3 of 14-3-3(sigma)/ERa PPI
分子名称: 14-3-3 protein sigma, 2-(2-cyanophenyl)sulfanyl-~{N}-(2-sulfanylethyl)benzamide, Estrogen receptor, ...
著者Sijbesma, E, Ottmann, C.
登録日2020-12-14
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers.
Acs Med.Chem.Lett., 12, 2021
2AXK
DownloadVisualize
BU of 2axk by Molmil
Solution structure of discrepin, a scorpion venom toxin blocking K+ channels.
分子名称: discrepin
著者Prochnicka-Chalufour, A, Corzo, G, Satake, H, Martin-Eauclaire, M.-F, Murgia, A.R, Prestipino, G, D'Suze, G, Possani, L.D, Delepierre, M.
登録日2005-09-05
公開日2006-06-20
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry, 45, 2006
1KEA
DownloadVisualize
BU of 1kea by Molmil
STRUCTURE OF A THERMOSTABLE THYMINE-DNA GLYCOSYLASE
分子名称: ACETATE ION, CHLORIDE ION, IRON/SULFUR CLUSTER, ...
著者Mol, C.D, Arvai, A.S, Begley, T.J, Cunningham, R.P, Tainer, J.A.
登録日2001-11-14
公開日2002-01-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.
J.Mol.Biol., 315, 2002
7B9R
DownloadVisualize
BU of 7b9r by Molmil
Cys-45-tethered stabilizer 4 of 14-3-3(sigma)/ERa PPI
分子名称: 14-3-3 protein sigma, 2-(2-cyanophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)benzamide, Estrogen receptor, ...
著者Sijbesma, E, Ottmann, C.
登録日2020-12-14
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers.
Acs Med.Chem.Lett., 12, 2021
7BA3
DownloadVisualize
BU of 7ba3 by Molmil
Cys-42-tethered stabilizer 6 of 14-3-3(sigma)/ERa PPI
分子名称: 14-3-3 protein sigma, 2-(4-bromanylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ...
著者Sijbesma, E, Ottmann, C.
登録日2020-12-15
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers.
Acs Med.Chem.Lett., 12, 2021
7BV7
DownloadVisualize
BU of 7bv7 by Molmil
INTS3 complexed with INTS6
分子名称: Integrator complex subunit 3, Integrator complex subunit 6
著者Jia, Y, Bharath, S.R, Song, H.
登録日2020-04-09
公開日2021-07-14
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the INTS3/INTS6 complex reveals the functional importance of INTS3 dimerization in DSB repair.
Cell Discov, 7, 2021
1KEH
DownloadVisualize
BU of 1keh by Molmil
Precursor structure of cephalosporin acylase
分子名称: precursor of cephalosporin acylase
著者Kim, Y, Kim, S.
登録日2001-11-16
公開日2002-05-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Precursor structure of cephalosporin acylase. Insights into autoproteolytic activation in a new N-terminal hydrolase family
J.Biol.Chem., 277, 2002
1KR0
DownloadVisualize
BU of 1kr0 by Molmil
Hevamine Mutant D125A/Y183F in Complex with Tetra-NAG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hevamine A, SULFATE ION
著者Rozeboom, H.J, Dijkstra, B.W.
登録日2002-01-08
公開日2002-01-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Expression and Characterization of Active Site Mutants of Hevamine, a Chitinase from the Rubber Tree Hevea brasiliensis.
Eur.J.Biochem., 269, 2002
4S1K
DownloadVisualize
BU of 4s1k by Molmil
Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 100 K
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyhedrin
著者Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I.
登録日2015-01-14
公開日2015-03-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.
Nat Commun, 6, 2015
1KR1
DownloadVisualize
BU of 1kr1 by Molmil
Hevamine Mutant D125A/E127A in Complex with Tetra-NAG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hevamine A, SULFATE ION
著者Rozeboom, H.J, Dijkstra, B.W.
登録日2002-01-08
公開日2002-01-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Expression and Characterization of Active Site Mutants of Hevamine, a Chitinase from the Rubber Tree Hevea brasiliensis.
Eur.J.Biochem., 269, 2002
4AKS
DownloadVisualize
BU of 4aks by Molmil
PatG macrocyclase domain
分子名称: THIAZOLINE OXIDASE/SUBTILISIN-LIKE PROTEASE
著者Koehnke, J, Bent, A, Houssen, W.E, Zollman, D, Morawitz, F, Shirran, S, Vendome, J, Nneoyiegbe, A.F, Trembleau, L, Botting, C.H, Smith, M.C.M, Jaspars, M, Naismith, J.H.
登録日2012-02-28
公開日2012-07-18
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The Mechanism of Patellamide Macrocyclization Revealed by the Characterization of the Patg Macrocyclase Domain.
Nat.Struct.Mol.Biol., 19, 2012
4N0K
DownloadVisualize
BU of 4n0k by Molmil
Atomic resolution crystal structure of a cytochrome c-calixarene complex
分子名称: 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, Cytochrome c iso-1, HEME C
著者McGovern, R.E, Pye, V.E, Crowley, P.B.
登録日2013-10-02
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献A cytochrome c-calixarene structure at atomic resolution
To be Published
3AJM
DownloadVisualize
BU of 3ajm by Molmil
Crystal structure of programmed cell death 10 in complex with inositol 1,3,4,5-tetrakisphosphate
分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Programmed cell death protein 10
著者Ding, J, Wang, D.C.
登録日2010-06-09
公開日2010-06-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human programmed cell death 10 complexed with inositol-(1,3,4,5)-tetrakisphosphate: a novel adaptor protein involved in human cerebral cavernous malformation.
Biochem.Biophys.Res.Commun., 399, 2010
1XLT
DownloadVisualize
BU of 1xlt by Molmil
Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex
分子名称: NAD(P) transhydrogenase subunit alpha part 1, NAD(P) transhydrogenase subunit beta, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Sundaresan, V, Chartron, J, Yamaguchi, M, Stout, C.D.
登録日2004-09-30
公開日2005-04-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Conformational Diversity in NAD(H) and Transhydrogenase Nicotinamide Nucleotide Binding Domains
J.Mol.Biol., 346, 2005
5ZHV
DownloadVisualize
BU of 5zhv by Molmil
Crystal structure of the PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with zinc ion
分子名称: Transcriptional regulator, ZINC ION
著者Meera, K, Pal, R.K, Arora, A, Biswal, B.K.
登録日2018-03-13
公開日2018-10-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional characterization of the transcriptional regulator Rv3488 ofMycobacterium tuberculosisH37Rv.
Biochem. J., 475, 2018
6R7Q
DownloadVisualize
BU of 6r7q by Molmil
Structure of XBP1u-paused ribosome nascent chain complex with Sec61.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R.
登録日2019-03-29
公開日2019-07-10
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
6JQ8
DownloadVisualize
BU of 6jq8 by Molmil
Crystal structure of HddC from Yersinia pseudotuberculosis complexed with GMP-PN
分子名称: AMINOPHOSPHONIC ACID-GUANYLATE ESTER, CITRIC ACID, MAGNESIUM ION, ...
著者Shin, D.H, Kim, M.S.
登録日2019-03-29
公開日2020-04-01
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.546 Å)
主引用文献GTP Preference of d-Glycero-alpha-d- manno -Heptose-1-Phosphate Guanylyltransferase from Yersinia pseudotuberculosis .
Int J Mol Sci, 21, 2019
4RQ1
DownloadVisualize
BU of 4rq1 by Molmil
Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine(8-oxoG) and dCTP soaked with MgCl2 for 1hr
分子名称: ACETATE ION, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ...
著者Vyas, R, Suo, Z.
登録日2014-10-31
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography.
J.Am.Chem.Soc., 137, 2015
2AJO
DownloadVisualize
BU of 2ajo by Molmil
NMR structure of the in-plane membrane anchor domain [1-28] of the monotopic NonStructural Protein 5A (NS5A) from the Bovine Viral Diarrhea Virus (BVDV)
分子名称: Nonstructural protein 5A
著者Sapay, N, Montserret, R, Chipot, C, Brass, V, Moradpour, D, Deleage, G, Penin, F.
登録日2005-08-02
公開日2005-08-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure and molecular dynamics of the in-plane membrane anchor of nonstructural protein 5A from bovine viral diarrhea virus.
Biochemistry, 45, 2006
2AJU
DownloadVisualize
BU of 2aju by Molmil
Cyrstal structure of cocaine catalytic antibody 7A1 Fab'
分子名称: ANTIBODY 7A1 FAB'
著者Zhu, X, Wilson, I.A.
登録日2005-08-02
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure, 14, 2006
3I2N
DownloadVisualize
BU of 3i2n by Molmil
Crystal Structure of WD40 repeats protein WDR92
分子名称: WD repeat-containing protein 92
著者Amaya, M.F, Li, Z, He, H, Seitova, A, Ni, S, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-06-29
公開日2009-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
4N5A
DownloadVisualize
BU of 4n5a by Molmil
Crystal structure of Efr3
分子名称: Protein EFR3
著者Wu, X, Chi, R.J, Baskin, J.M, Lucast, L, Burd, C.G, De Camilli, P, Reinisch, K.M.
登録日2013-10-09
公開日2014-01-22
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (3.204 Å)
主引用文献Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.
Dev.Cell, 28, 2014
7BK4
DownloadVisualize
BU of 7bk4 by Molmil
Crystal structure of RXRalpha ligand binding domain in complex with a fragment of the TIF2 coactivator
分子名称: 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
著者le Maire, A, Bourguet, W.
登録日2021-01-15
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR).
J.Mol.Biol., 433, 2021
1F9O
DownloadVisualize
BU of 1f9o by Molmil
Crystal structure of the cellulase Cel48F from C. Cellulolyticum with the thiooligosaccharide inhibitor PIPS-IG3
分子名称: CALCIUM ION, ENDO-1,4-BETA-GLUCANASE F, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-iodophenyl 1,4-dithio-beta-D-glucopyranoside
著者Parsiegla, G, Reverbel-Leroy, C, Tardif, C, Belaich, J.P, Driguez, H, Haser, R.
登録日2000-07-11
公開日2000-08-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of the Cellulase Cel48F in Complex with Inhibitors and Substrates Give Insights Into its Processive Action
Biochemistry, 39, 2000

224004

件を2024-08-21に公開中

PDB statisticsPDBj update infoContact PDBjnumon