PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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3TUE	The structure of tryparedoxin peroxidase I from Leishmania major 分子名称: Tryparedoxin peroxidase 著者 Fiorillo, A, Ilari, A, Colotti, G. 登録日 2011-09-16 公開日 2012-09-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of leishmania detoxification pathway. Plos Negl Trop Dis, 6, 2012
3U9Y	Crystal structure of human tankyrase 2 catalytic domain in complex with olaparib 分子名称: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, GLYCEROL, SULFATE ION, ... 著者 Narwal, M, Lehtio, L. 登録日 2011-10-20 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of selective inhibition of human tankyrases. J.Med.Chem., 55, 2012
4I4E	Structure of Focal Adhesion Kinase catalytic domain in complex with hinge binding pyrazolobenzothiazine compound. 分子名称: Focal adhesion kinase 1, [4-(2-hydroxyethyl)piperidin-1-yl][4-(5-methyl-4,4-dioxido-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazin-8-yl)phenyl]methanone 著者 Skene, R.J, Hosfield, D.J. 登録日 2012-11-27 公開日 2013-03-06 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure-based discovery of cellular-active allosteric inhibitors of FAK. Bioorg.Med.Chem.Lett., 23, 2013
3U8U	Crystal structure of Human Apurinic/Apyridinimic Endonuclease, Ape1 in a new crystal form 分子名称: CHLORIDE ION, DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION 著者 Agarwal, R, Naidu, M.D. 登録日 2011-10-17 公開日 2011-10-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of Human Apurinic/Apyridinimic Endonuclease, Ape1 in a new crystal form To be Published
3TZ0	Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex 分子名称: (2S)-2-chloro-4-methylpentanoic acid, [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 著者 Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T. 登録日 2011-09-26 公開日 2012-10-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase. Proc.Natl.Acad.Sci.USA, 110, 2013
3TJK	Crystal Structure of human peroxiredoxin IV C245A mutant in reduced form 分子名称: Peroxiredoxin-4 著者 Cao, Z, Tavender, T.J, Roszak, A.W, Cogdell, R.J, Bulleid, N.J. 登録日 2011-08-24 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle. J.Biol.Chem., 286, 2011
4KR1	Crystal structure of the kinetechore protein Iml3 from budding yeast 分子名称: Central kinetochore subunit IML3 著者 Tao, Y, Guo, Q, Teng, M. 登録日 2013-05-16 公開日 2013-12-18 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly Acta Crystallogr.,Sect.D, 69, 2013
3TKP	Crystal structure of full-length human peroxiredoxin 4 in the reduced form 分子名称: Peroxiredoxin-4 著者 Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. 登録日 2011-08-28 公開日 2011-10-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
4KPA	Crystal structure of cytochrome P450 BM-3 in complex with N-palmitoylglycine (NPG) 分子名称: Cytochrome P450 BM-3, N-PALMITOYLGLYCINE, PROTOPORPHYRIN IX CONTAINING FE 著者 Amadeo, G.A, Catalano, J, McDermott, A.E, Tong, L. 登録日 2013-05-13 公開日 2013-07-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Evidence: A Single Charged Residue Affects Substrate Binding in Cytochrome P450 BM-3. Biochemistry, 52, 2013
3TLM	Crystal Structure of Endoplasmic Reticulum Ca2+-ATPase (SERCA) From Bovine Muscle 分子名称: CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Sacchetto, R, Bertipaglia, I, Giannetti, S, Cendron, L, Mascarello, F, Damiani, E, Carafoli, E, Zanotti, G. 登録日 2011-08-30 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure of sarcoplasmic reticulum Ca(2+)-ATPase (SERCA) from bovine muscle. J.Struct.Biol., 178, 2012
1BZ2	STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE 分子名称: TRNA 著者 Durant, P.C, Davis, D.R. 登録日 1998-11-05 公開日 1999-04-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine. J.Mol.Biol., 285, 1999
3TOB	Human MOF E350Q crystal structure with active site lysine partially acetylated 分子名称: CHLORIDE ION, ZINC ION, histone acetyltransferase MYST1 著者 Yuan, H, Ding, E.C, Marmorstein, R. 登録日 2011-09-04 公開日 2011-11-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
4KVL	Crystal structure of Oryza sativa fatty acid alpha-dioxygenase Y379F with palmitic acid 分子名称: CALCIUM ION, CHLORIDE ION, Fatty acid alpha-oxidase, ... 著者 Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. 登録日 2013-05-22 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide. Protein Sci., 22, 2013
2B8K	12-subunit RNA Polymerase II 分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... 著者 Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J. 登録日 2005-10-07 公開日 2006-06-20 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (4.15 Å) 主引用文献 Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model. Structure, 14, 2006
3U8I	Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism 分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... 著者 Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F. 登録日 2011-10-17 公開日 2012-10-17 最終更新日 2013-06-12 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes. J.Biol.Chem., 288, 2013
3UA9	Crystal structure of human tankyrase 2 in complex with a selective inhibitor 分子名称: 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... 著者 Narwal, M, Lehtio, L. 登録日 2011-10-21 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis of selective inhibition of human tankyrases. J.Med.Chem., 55, 2012
1BZT	STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE 分子名称: TRNA 著者 Durant, P.C, Davis, D.R. 登録日 1998-11-05 公開日 1999-04-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine. J.Mol.Biol., 285, 1999
4OIP	Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077, ATP, and CMPcPP 分子名称: (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... 著者 Zhang, Y, Ebright, R.H, Arnold, E. 登録日 2014-01-20 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
4K90	Extracellular metalloproteinase from Aspergillus 分子名称: BORIC ACID, CALCIUM ION, Extracellular metalloproteinase mep, ... 著者 Fernandez, D, Russi, S, Vendrell, J, Monod, M, Pallares, I. 登録日 2013-04-19 公開日 2013-10-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus. Acta Crystallogr.,Sect.D, 69, 2013
1BW7	SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING A REPLICABLE DIFLUOROTOLUENE-ADENINE PAIR 分子名称: DNA (5'-D(*CP*GP*CP*AP*TP*(DFT)P*GP*TP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*AP*CP*AP*AP*TP*GP*CP*G)-3') 著者 Guckian, K.M, Krugh, T.R, Kool, E.T. 登録日 1998-09-30 公開日 1998-10-07 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Solution structure of a DNA duplex containing a replicable difluorotoluene-adenine pair. Nat.Struct.Biol., 5, 1998
3Q76	Structure of human neutrophil elastase (uncomplexed) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Neutrophil elastase, ... 著者 Hansen, G, Niefind, K. 登録日 2011-01-04 公開日 2011-05-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.861 Å) 主引用文献 Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor. J.Mol.Biol., 409, 2011
4O6K	The crystal structure of zebrafish IL-22 分子名称: Interleukin 22 著者 Siupka, P, Hamming, O.J, Fretaud, M, Luftalla, G, Levraud, J.P, Hartmann, R. 登録日 2013-12-21 公開日 2014-09-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22. Genes Immun., 15, 2014
1ZOT	crystal structure analysis of the CyaA/C-Cam with PMEAPP 分子名称: (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE, CALCIUM ION, Calmodulin, ... 著者 Guo, Q, Tang, W.J. 登録日 2005-05-13 公開日 2005-08-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin. Embo J., 24, 2005
1YVF	Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145 分子名称: (2Z)-2-(BENZOYLAMINO)-3-[4-(2-BROMOPHENOXY)PHENYL]-2-PROPENOIC ACID, CHLORIDE ION, GLYCEROL, ... 著者 Pfefferkorn, J.A, Greene, M.L, Nugent, R.A, Gross, R.J, Mitchell, M.A, Finzel, B.C, Harris, M.S, Wells, P.A, Shelly, J.A, Anstadt, R.A, Kilkuskie, R.E, Kopta, L.A, Schwende, F.J. 登録日 2005-02-15 公開日 2005-04-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid. Bioorg.Med.Chem.Lett., 15, 2005
3Q77	Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxyethyl (4R)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate, ... 著者 Hansen, G, Niefind, K. 登録日 2011-01-04 公開日 2011-05-11 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor. J.Mol.Biol., 409, 2011

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