3SZ7
 
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5BKC
 
 | Crystal structure of AAD-1 in complex with (R)-diclofop, Mn(II), and 2-oxoglutarate | 分子名称: | (2R)-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}propanoic acid, (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, ... | 著者 | Chekan, J.R, Nair, S.K. | 登録日 | 2019-06-02 | 公開日 | 2019-06-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
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1RCE
 
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1RCI
 
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2GL3
 
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1IFY
 
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1BW3
 
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1ZCM
 
 | Human calpain protease core inhibited by ZLLYCH2F | 分子名称: | CALCIUM ION, Calpain 1, large [catalytic] subunit, ... | 著者 | Li, Q, Hanzlik, R.P, Weaver, R.F, Schonbrunn, E. | 登録日 | 2005-04-12 | 公開日 | 2006-01-31 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core Biochemistry, 45, 2006
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2GNF
 
 | Protein kinase A fivefold mutant model of Rho-kinase with Y-27632 | 分子名称: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... | 著者 | Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. | 登録日 | 2006-04-10 | 公開日 | 2006-05-23 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
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3T3X
 
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3T42
 
 | Human aldose reductase in complex with a nitrile-containing IDD inhibitor | 分子名称: | Aldose reductase, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xu, L, Cohen, A.E, Boxer, S.G. | 登録日 | 2011-07-25 | 公開日 | 2011-10-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Electrostatic Fields near the Active Site of Human Aldose Reductase: 2. New Inhibitors and Complications Caused by Hydrogen Bonds. Biochemistry, 50, 2011
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1ZHX
 
 | Structure of yeast oxysterol binding protein Osh4 in complex with 25-hydroxycholesterol | 分子名称: | 25-HYDROXYCHOLESTEROL, KES1 protein | 著者 | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | 登録日 | 2005-04-26 | 公開日 | 2005-09-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1C3R
 
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2GMV
 
 | PEPCK complex with a GTP-competitive inhibitor | 分子名称: | MANGANESE (II) ION, N-(4-{[3-BUTYL-1-(2-FLUOROBENZYL)-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YL]METHYL}PHENYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE, PHOSPHOENOLPYRUVATE, ... | 著者 | Dunten, P. | 登録日 | 2006-04-07 | 公開日 | 2007-05-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase. Bioorg.Med.Chem.Lett., 17, 2007
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2GNG
 
 | Protein kinase A fivefold mutant model of Rho-kinase | 分子名称: | cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, alpha-catalytic subunit | 著者 | Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. | 登録日 | 2006-04-10 | 公開日 | 2006-05-23 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
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4K95
 
 | Crystal Structure of Parkin | 分子名称: | E3 ubiquitin-protein ligase parkin, ZINC ION | 著者 | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | 登録日 | 2013-04-19 | 公開日 | 2013-05-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (6.499 Å) | 主引用文献 | Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science, 340, 2013
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1RCG
 
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1RCD
 
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2BKH
 
 | Myosin VI nucleotide-free (MDInsert2) crystal structure | 分子名称: | CALCIUM ION, CALMODULIN, GLYCEROL, ... | 著者 | Menetrey, J, Bahloul, A, Yengo, C, Wells, A, Morris, C, Sweeney, H.L, Houdusse, A. | 登録日 | 2005-02-16 | 公開日 | 2005-06-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Structure of the Myosin Vi Motor Reveals the Mechanism of Directionality Reversal Nature, 435, 2005
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1RRG
 
 | NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, DIMERIC CRYSTAL FORM | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAT ADP-RIBOSYLATION FACTOR-1 | 著者 | Greasley, S.E, Jhoti, H, Bax, B. | 登録日 | 1995-12-16 | 公開日 | 1996-06-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms. Nat.Struct.Biol., 2, 1995
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1BRQ
 
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3RIL
 
 | The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease | 分子名称: | (3S,4R,5R,6S)-azepane-3,4,5,6-tetrol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ... | 著者 | Orwig, S.D, Lieberman, R.L. | 登録日 | 2011-04-13 | 公開日 | 2012-03-14 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease Biochemistry, 50, 2011
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4IU9
 
 | Crystal structure of a membrane transporter | 分子名称: | Nitrite extrusion protein 2 | 著者 | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | 登録日 | 2013-01-20 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Structure and mechanism of a nitrate transporter. Cell Rep, 3, 2013
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1RRF
 
 | NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, MONOMERIC CRYSTAL FORM | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAT ADP-RIBOSYLATION FACTOR-1 | 著者 | Greasley, S.E, Jhoti, H, Bax, B. | 登録日 | 1995-12-16 | 公開日 | 1996-06-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms. Nat.Struct.Biol., 2, 1995
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3RJI
 
 | Ternary complex of DNA Polymerase Beta with a gapped DNA containing 8odG at template position paired with non-hydrolyzable dCTP analog (dCMP(CF2)PP) | 分子名称: | 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]cytidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Batra, V.K, Beard, W.A, Wilson, S.H. | 登録日 | 2011-04-15 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Binary complex crystal structure of DNA polymerase beta reveals multiple conformations of the templating 8-oxoguanine lesion Proc.Natl.Acad.Sci.USA, 109, 2012
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