Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2GMV

PEPCK complex with a GTP-competitive inhibitor

Summary for 2GMV
Entry DOI10.2210/pdb2gmv/pdb
Related1KHB 1M51 1NHX
DescriptorPhosphoenolpyruvate carboxykinase, cytosolic, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... (5 entities in total)
Functional Keywordsgluconeogenesis, xanthine, inhibitor, lyase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight140070.98
Authors
Dunten, P. (deposition date: 2006-04-07, release date: 2007-05-29, Last modification date: 2024-02-14)
Primary citationPietranico, S.L.,Foley, L.H.,Huby, N.,Yun, W.,Dunten, P.,Vermeulen, J.,Wang, P.,Toth, K.,Ramsey, G.,Gubler, M.L.,Wertheimer, S.J.
C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase.
Bioorg.Med.Chem.Lett., 17:3835-3839, 2007
Cited by
PubMed: 17532214
DOI: 10.1016/j.bmcl.2007.05.013
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon