2GMV
PEPCK complex with a GTP-competitive inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphoenolpyruvate carboxykinase, cytosolic | polymer | 625 | 69529.7 | 2 | UniProt (P35558) Pfam (PF17297) Pfam (PF00821) | Homo sapiens (human) | Phosphoenolpyruvate carboxylase, PEPCK-C |
| 2 | C, F (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, G (A, B) | PHOSPHOENOLPYRUVATE | non-polymer | 168.0 | 2 | Chemie (PEP) | |||
| 4 | E (A) | N-(4-{[3-BUTYL-1-(2-FLUOROBENZYL)-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YL]METHYL}PHENYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE | non-polymer | 565.6 | 1 | Chemie (UN8) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 622 (UniProt: P35558)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Glu -1 | - | cloning artifact |
| Leu 0 | - | cloning artifact |
| Leu 184 | Val 184 | variant |
| Val 267 | Ile 267 | variant |
| Asp 586 | Glu 586 | variant |
| Val 597 | Glu 597 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 139059.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1011.6 | |
| All* | Total formula weight | 140071.0 |
