PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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4S20	Structural basis for transcription reactivation by RapA 分子名称: 5'-D(P*AP*CP*GP*AP*CP*TP*GP*AP*GP*CP*CP*GP*AP*TP*G)-3', 5'-R(P*AP*UP*CP*GP*GP*CP*UP*CP*A)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2015-01-16 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.7 Å) 主引用文献 Structural basis for transcription reactivation by RapA. Proc.Natl.Acad.Sci.USA, 112, 2015
4IBB	Ebola virus VP35 bound to small molecule 分子名称: Polymerase cofactor VP35, {4-[(5R)-3-hydroxy-2-oxo-4-(thiophen-2-ylcarbonyl)-5-(2,4,5-trimethylphenyl)-2,5-dihydro-1H-pyrrol-1-yl]phenyl}acetic acid 著者 Brown, C.S, Leung, D.W, Xu, W, Borek, D.M, Otwinowski, Z, Ramanan, P, Stubbs, A.J, Peterson, D.S, Binning, J.M, Amarasinghe, G.K, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-12-08 公開日 2014-02-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.752 Å) 主引用文献 In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity. J.Mol.Biol., 426, 2014
2ISO	Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate 分子名称: 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... 著者 Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A. 登録日 2006-10-18 公開日 2007-01-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta. Biochemistry, 46, 2007
8IDF	Crystal structure of human TUT1 complexed with U6 snRNA 分子名称: RNA (53-MER), Speckle targeted PIP5K1A-regulated poly(A) polymerase, ZINC ION 著者 Yamashita, S, Tomita, K. 登録日 2023-02-13 公開日 2023-08-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Mechanism of U6 snRNA oligouridylation by human TUT1. Nat Commun, 14, 2023
8GXS	PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. 登録日 2022-09-21 公開日 2022-11-02 実験手法 ELECTRON MICROSCOPY (4.16 Å) 主引用文献 Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
8GXQ	PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. 登録日 2022-09-21 公開日 2022-11-02 実験手法 ELECTRON MICROSCOPY (5.04 Å) 主引用文献 Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
4WC4	tRNA-processing enzyme complex 2 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Poly A polymerase, RNA (74-MER) 著者 Yamashita, S, Tomita, K. 登録日 2014-09-04 公開日 2015-04-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.501 Å) 主引用文献 Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
5FLX	Mammalian 40S HCV-IRES complex 分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... 著者 Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. 登録日 2015-10-28 公開日 2015-12-23 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
4R66	Ternary complex crystal structure of E295K mutant of DNA polymerase Beta 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Beard, W.A, Wilson, S.H. 登録日 2014-08-22 公開日 2014-10-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Substrate-induced DNA Polymerase beta Activation. J.Biol.Chem., 289, 2014
2IHM	Polymerase mu in ternary complex with gapped 11mer DNA duplex and bound incoming nucleotide 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*T)-3', 5'-D(*CP*GP*GP*CP*AP*AP*TP*AP*CP*TP*G)-3', ... 著者 Moon, A.F, Pedersen, L.C, Kunkel, T.A. 登録日 2006-09-26 公開日 2006-12-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insight into the substrate specificity of DNA Polymerase mu. Nat.Struct.Mol.Biol., 14, 2007
4QW9	TERNARY CRYSTAL STRUCTURES of A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)FTC-PPNP 分子名称: CALCIUM ION, DNA (5'-D(P*CP*AP*GP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3'), ... 著者 Gaur, V, Suo, Z. 登録日 2014-07-16 公開日 2014-08-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase. Nucleic Acids Res., 42, 2014
4QWC	Ternary Crystal Structures of a Y-family DNA polymerase DPO4 from Sulfobus Solfataricus in Comples with DNA and L-DCDP 分子名称: 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy(phosphonooxy)phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, ACETATE ION, CALCIUM ION, ... 著者 Vyas, R, Suo, Z. 登録日 2014-07-16 公開日 2014-08-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase. Nucleic Acids Res., 42, 2014
4QWE	TERNARY CRYSTAL STRUCTURES of A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)FTC-DP 分子名称: CALCIUM ION, DNA (5'-D(P*CP*AP*GP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3'), ... 著者 Gaur, V, Suo, Z. 登録日 2014-07-16 公開日 2014-08-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase. Nucleic Acids Res., 42, 2014
4QWD	TERNARY CRYSTAL STRUCTURES of A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH DNA AND (-)3TC-PPNP 分子名称: CALCIUM ION, DNA (5'-D(P*CP*AP*GP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3'), ... 著者 Gaur, V, Suo, Z. 登録日 2014-07-16 公開日 2014-08-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase. Nucleic Acids Res., 42, 2014
4WC0	tRNA-processing enzyme with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Poly A polymerase 著者 Yamashita, S, Tomita, K. 登録日 2014-09-04 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
8VFH	Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dC 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(FAP))-3'), ... 著者 Oden, P.N, Ryan, B.J, Freudenthal, B.D. 登録日 2023-12-21 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
8VFA	Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Oden, P.N, Ryan, B.J, Freudenthal, B.D. 登録日 2023-12-21 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
8VFB	Ternary DNA Polymerase Beta bound to DNA containing primer terminal dA base-paired with FapydG 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Oden, P.N, Ryan, B.J, Freudenthal, B.D. 登録日 2023-12-21 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
8VFD	Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog 分子名称: 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Oden, P.N, Ryan, B.J, Freudenthal, B.D. 登録日 2023-12-21 公開日 2024-05-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
5M9D	Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide 分子名称: Regulator of Ty1 transposition protein 103, THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER 著者 Jasnovidova, O, Kubicek, K, Stefl, R. 登録日 2016-11-01 公開日 2017-10-11 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of the RNAPII CTDsome with Rtt103. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6XBU	polymerase domain of polymerase-theta 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*TP*CP*AP*TP*TP*G)-3'), DNA polymerase theta, ... 著者 Chen, X, Pomerantz, R, Zhao, J. 登録日 2020-06-07 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.29 Å) 主引用文献 Pol theta reverse transcribes RNA and promotes RNA-templated DNA repair. Sci Adv, 7, 2021
4WBY	tRNA-processing enzyme (apo form I) 分子名称: GLYCEROL, Poly A polymerase, SULFATE ION 著者 Yamashita, S, Tomita, K. 登録日 2014-09-04 公開日 2015-04-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
8VFI	Ternary DNA Polymerase Beta bound to DNA containing primer terminal FapydG base-paired with a dA 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Oden, P.N, Ryan, B.J, Freudenthal, B.D. 登録日 2023-12-21 公開日 2024-05-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta. Nucleic Acids Res., 52, 2024
7OMA	Thosea asigna virus RdRP domain elongation complex 分子名称: MAGNESIUM ION, PYROPHOSPHATE 2-, RNA (5'-R(P*AP*AP*AP*UP*UP*UP*U)-3'), ... 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
7OM2	Thosea asigna virus RdRP domain in complex with Mg+2 分子名称: GLYCEROL, MAGNESIUM ION, RNA-dependent RNA polymerase, ... 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021

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