8FJB
 
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5HYJ
 | | 1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA | | 分子名称: | ALA-GLN-TRP-GLY-PRO-ASP-PRO-ALA-ALA-ALA, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | | 登録日 | 2016-02-01 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | A "hotspot" for autoimmune T cells in type 1 diabetes.
J.Clin.Invest., 126, 2016
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7PHR
 | | Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Susac, L, Thomas, C, Tampe, R. | | 登録日 | 2021-08-18 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.
Cell, 185, 2022
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4MVB
 | | 42F3 pCPB7/H-2Ld Complex | | 分子名称: | 42F3 alpha VmCh, 42F3 beta VmCh, H-2 class I histocompatibility antigen, ... | | 著者 | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | | 登録日 | 2013-09-23 | | 公開日 | 2015-08-19 | | 最終更新日 | 2018-09-26 | | 実験手法 | X-RAY DIFFRACTION (3.088 Å) | | 主引用文献 | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
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7XXA
 | | Complex of Echo 18 and FcRn at pH7.4 | | 分子名称: | IgG receptor FcRn large subunit p51, VP1, VP2, ... | | 著者 | Liu, C.C, Qu, X. | | 登録日 | 2022-05-29 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18.
Mbio, 13, 2022
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8EUQ
 | | Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... | | 著者 | Kassardjian, A, Julien, J.-P. | | 登録日 | 2022-10-19 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses.
Cell Rep, 42, 2023
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6QZA
 | | HLA-DR1 with GMF Influenza PB1 Peptide | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | 著者 | Greenshields-Watson, A, Rizkallah, P.J. | | 登録日 | 2019-03-11 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
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3CUP
 | | Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, H-2 class II histocompatibility antigen, ... | | 著者 | Corper, A.L, Yoshida, K, Teyton, L, Wilson, I.A. | | 登録日 | 2008-04-16 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
To be Published
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4L29
 | | Structure of wtMHC class I with NY-ESO1 double mutant | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | | 著者 | Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. | | 登録日 | 2013-06-04 | | 公開日 | 2013-12-25 | | 最終更新日 | 2014-02-26 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
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3VWJ
 | | Ternary crystal structure of the human NKT TCR-CD1d-C20:2 complex | | 分子名称: | (11Z,14E)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | | 著者 | Wun, K.S, Rossjohn, J. | | 登録日 | 2012-08-24 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.093 Å) | | 主引用文献 | Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex
J.Biol.Chem., 287, 2012
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6DFS
 | | mouse TCR I.29 in complex with IAg7-p8E9E6ss | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A-D alpha chain, ... | | 著者 | Wang, Y, Dai, S. | | 登録日 | 2018-05-15 | | 公開日 | 2019-04-17 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
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1DDH
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3UBX
 | | Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex | | 分子名称: | (11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-10-25 | | 公開日 | 2011-11-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for the recognition of C20:2-alpha GalCer by the invariant natural killer T cell receptor-like antibody L363.
J.Biol.Chem., 287, 2012
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6DCQ
 | | Ectodomain of full length, wild type HIV-1 glycoprotein clone PC64M18C043 in complex with PGT151 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Rantalainen, K. | | 登録日 | 2018-05-08 | | 公開日 | 2018-06-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23, 2018
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5VME
 | | Crystal structure of human IgG1 Fc K248E, T437R mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, human IgG1 Fc K248E,T437R mutant | | 著者 | Armstrong, A.A, Gilliland, G.L. | | 登録日 | 2017-04-27 | | 公開日 | 2017-08-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Functional optimization of agonistic antibodies to OX40 receptor with novel Fc mutations to promote antibody multimerization.
MAbs, 9, 2017
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3EO1
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4UAO
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4WWK
 | | Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting molecule CD1d, and Beta-2-microglobulin | | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | | 著者 | Le Nours, J, Praveena, T, Pellicci, D.G, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, A, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | | 登録日 | 2014-11-11 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
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1F3J
 | | HISTOCOMPATIBILITY ANTIGEN I-AG7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, LYSOZYME C, ... | | 著者 | Latek, R.R, Unanue, E.R, Fremont, D.H. | | 登録日 | 2000-06-04 | | 公開日 | 2000-09-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice.
Immunity, 12, 2000
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6YJP
 | | Crystal structure of a complex between glycosylated NKp30 and its deglycosylated tumour ligand B7-H6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Natural cytotoxicity triggering receptor 3, Natural cytotoxicity triggering receptor 3 ligand 1 | | 著者 | Skalova, T, Dohnalek, J, Skorepa, O, Kalouskova, B, Pazicky, S, Blaha, J, Vanek, O. | | 登録日 | 2020-04-04 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N -Glycosylation.
Cancers (Basel), 12, 2020
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5W1W
 | | Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex | | 分子名称: | Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... | | 著者 | Gras, S, Walpole, N, Farenc, C, Rossjohn, J. | | 登録日 | 2017-06-05 | | 公開日 | 2017-10-04 | | 最終更新日 | 2018-01-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
J. Biol. Chem., 292, 2017
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6UTA
 | | Crystal structure of Z004 iGL Fab in complex with ZIKV EDIII | | 分子名称: | Env, Z004 iGL Fab heavy chain, Z004 iGL Fab light chain | | 著者 | Esswein, S.R, Gristick, H.B, Keeffe, J.R, Bjorkman, P.J. | | 登録日 | 2019-10-29 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 117, 2020
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3SDC
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3SJV
 | | Crystal structure of the RL42 TCR in complex with HLA-B8-FLR | | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ... | | 著者 | Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J. | | 登録日 | 2011-06-22 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.
J.Immunol., 188, 2012
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1KTL
 | | The human non-classical major histocompatibility complex molecule HLA-E | | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | | 著者 | Holmes, M.A, Strong, R.K. | | 登録日 | 2002-01-16 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities
J.Biol.Chem., 278, 2003
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