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1MWL
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Crystal structure of geneticin bound to the eubacterial 16S rRNA A site
分子名称: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', GENETICIN
著者Vicens, Q, Westhof, E.
登録日2002-09-30
公開日2003-02-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide
J.Mol.Biol., 326, 2003
2F43
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Rat liver F1-ATPase
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase alpha chain, ...
著者Chen, C, Saxena, A.K, Simcoke, W.N, Garboczi, D.N, Pedersen, P.L, Ko, Y.H.
登録日2005-11-22
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mitochondrial ATP synthase: Crystal structure of the catalytic F1 unit in a vanadate-induced transition-like state and implications for mechanism.
J.Biol.Chem., 281, 2006
3WNM
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D308A mutant of Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase complexed with isomaltoheptaose
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Cycloisomaltooligosaccharide glucanotransferase, ...
著者Suzuki, N, Fujimoto, Z, Kim, Y.M, Momma, M, Kishine, N, Suzuki, R, Suzuki, S, Kitamura, S, Kobayashi, M, Kimura, A, Funane, K.
登録日2013-12-10
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural elucidation of the cyclization mechanism of alpha-1,6-glucan by Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase.
J.Biol.Chem., 289, 2014
2PNM
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Crystal Structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P6122
分子名称: Protease VP4
著者Paetzel, M, Lee, J, Feldman, A.R, Delmas, B.
登録日2007-04-24
公開日2007-06-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
J.Biol.Chem., 282, 2007
1MWJ
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Crystal Structure of a MUG-DNA pseudo substrate complex
分子名称: 5'-D(*CP*GP*CP*GP*A*GP*(DU)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase
著者Barrett, T.E, Scharer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G.L, Pearl, L.H.
登録日2002-09-30
公開日2002-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structure of a thwarted mismatch glycosylase DNA repair complex
Embo J., 18, 1999
1TK8
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T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ...
著者Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T.
登録日2004-06-08
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
Embo J., 23, 2004
4BA6
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High Resolution structure of the C-terminal family 65 Carbohydrate Binding Module (CBM65B) of endoglucanase Cel5A from Eubacterium cellulosolvens
分子名称: Endoglucanase cel5A, GLYCEROL
著者Venditto, I, Luis, A.S, Basle, A, Temple, M, Ferreira, L.M.A, Fontes, C.M.G.A, Gilbert, H.J, Najmudin, S.
登録日2012-09-11
公開日2012-12-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Understanding how noncatalytic carbohydrate binding modules can display specificity for xyloglucan.
J. Biol. Chem., 288, 2013
2OZA
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Structure of p38alpha complex
分子名称: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14
著者White, A, Pargellis, C.A, Studts, J.M, Werneburg, B.G, Farmer II, B.T.
登録日2007-02-25
公開日2007-04-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of MAPK-activated protein kinase 2:p38 assembly
Proc.Natl.Acad.Sci.Usa, 104, 2007
4B8E
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PRY-SPRY domain of Trim25
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 UBIQUITIN/ISG15 LIGASE TRIM25
著者Kershaw, N.J, D'Cruz, A.A, Nicola, N.A, Nicholson, S.E, Babon, J.J.
登録日2012-08-27
公開日2013-09-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.779 Å)
主引用文献Crystal Structure of the Trim25 B30.2 (Pryspry) Domain: A Key Component of Antiviral Signaling.
Biochem.J., 456, 2013
3S20
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Crystal structure of cerulenin bound Xanthomonas campestri OleA (soak)
分子名称: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ...
著者Goblirsch, B.R, Wilmot, C.M.
登録日2011-05-16
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8796 Å)
主引用文献Crystal Structures of Xanthomonas campestris OleA Reveal Features That Promote Head-to-Head Condensation of Two Long-Chain Fatty Acids.
Biochemistry, 51, 2012
1M46
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CRYSTAL STRUCTURE OF MLC1P BOUND TO IQ4 OF MYO2P, A CLASS V MYOSIN
分子名称: IQ4 Motif from MYO2P, A Class V Myosin, Myosin light chain
著者Terrak, M, Dominguez, R.
登録日2002-07-02
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications
Embo J., 22, 2003
1M4I
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Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-Complex with Coenzyme A and Kanamycin A
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 2'-N-acetyltransferase, COENZYME A, ...
著者Vetting, M.W, Hegde, S.S, Javid-Majd, F, Blanchard, J.S, Roderick, S.L.
登録日2002-07-02
公開日2002-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates.
Nat.Struct.Biol., 9, 2002
3WV1
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Crystal structure of the catalytic domain of MMP-13 complexed with 4-(2-((6-fluoro-2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydroquinazolin-5-yl)oxy)ethyl)benzoic acid
分子名称: 4-[2-({6-fluoro-2-[(3-methoxybenzyl)carbamoyl]-4-oxo-3,4-dihydroquinazolin-5-yl}oxy)ethyl]benzoic acid, CALCIUM ION, Collagenase 3, ...
著者Oki, H, Tanaka, Y.
登録日2014-05-12
公開日2015-05-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Discovery of novel, highly potent, and selective quinazoline-2-carboxamide-based matrix metalloproteinase (MMP)-13 inhibitors without a zinc binding group using a structure-based design approach
J.Med.Chem., 57, 2014
1M4G
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Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-Complex with Coenzyme A and Ribostamycin
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 2'-N-acetyltransferase, COENZYME A, ...
著者Vetting, M.W, Hegde, S.S, Javid-Majd, F, Blanchard, J.S, Roderick, S.L.
登録日2002-07-02
公開日2002-08-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates.
Nat.Struct.Biol., 9, 2002
3UL1
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Mouse importin alpha: nucleoplasmin cNLS peptide complex
分子名称: Importin subunit alpha-2, Nucleoplasmin
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
1MUU
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2.0 A crystal structure of GDP-mannose dehydrogenase
分子名称: GDP-mannose 6-dehydrogenase, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER, ...
著者Snook, C.F, Tipton, P.A, Beamer, L.J.
登録日2002-09-24
公開日2003-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of GDP-mannose dehydrogenase: A key enzyme of alginate biosynthesis in P. aeruginosa
Biochemistry, 42, 2003
3WLB
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HLA-A24 in complex with HIV-1 Nef126-10(8T10F)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A, Han, C.
登録日2013-11-08
公開日2014-06-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Switching and emergence of CTL epitopes in HIV-1 infection
Retrovirology, 11, 2014
1MU9
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Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Vanadate Complex
分子名称: GLYCEROL, Tyrosyl-DNA Phosphodiesterase, VANADATE ION
著者Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
登録日2002-09-23
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2002
1N3J
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Structure and Substrate of a Histone H3 Lysine Methyltransferase from Paramecium Bursaria Chlorella Virus 1
分子名称: Histone H3 Lysine Methyltransferase
著者Manzur, K.L, Farooq, A, Zeng, L, Plotnikova, O, Sachchidanand, Koch, A.W, Zhou, M.-M.
登録日2002-10-28
公開日2003-01-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.
Nat.Struct.Biol., 10, 2003
4C29
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Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation
分子名称: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Blenner, M.A, Dong, X, Springer, T.A.
登録日2013-08-16
公開日2014-01-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
1IG9
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Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase
分子名称: 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ...
著者Franklin, M.C, Wang, J, Steitz, T.A.
登録日2001-04-17
公開日2001-06-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase
Cell(Cambridge,Mass.), 105, 2001
1J1U
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Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine
分子名称: MAGNESIUM ION, TYROSINE, Tyrosyl-tRNA synthetase, ...
著者Kobayashi, T, Nureki, O, Ishitani, R, Tukalo, M, Cusack, S, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-12-17
公開日2003-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion
NAT.STRUCT.BIOL., 10, 2003
4C2B
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Crystal Structure of High-Affinity von Willebrand Factor A1 domain with Disulfide Mutation in Complex with High Affinity GPIb alpha
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ...
著者Blenner, M.A, Dong, X, Springer, T.A.
登録日2013-08-16
公開日2014-01-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Towards the Structural Basis of Regulation of Von Willebrand Factor Binding to Glycoprotein Ib
J.Biol.Chem., 289, 2014
1IYU
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LIPOYL DOMAIN OF PYRUVATE DEHYDROGENASE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX
著者Berg, A, Vervoort, J, De Kok, A.
登録日1996-09-25
公開日1997-03-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure in solution of the N-terminal lipoyl domain of the pyruvate dehydrogenase complex from Azotobacter vinelandii.
Eur.J.Biochem., 244, 1997
4CBS
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X-ray structure of quintuple mutant of human alanine glyoxylate aminotransferase, AGXT_RHEAM
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE--PYRUVATE AMINOTRANSFERASE
著者Yunta, C, Albert, A.
登録日2013-10-16
公開日2014-07-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Consensus-Based Approach for Gene/Enzyme Replacement Therapies and Crystallization Strategies: The Case of Human Alanine:Glyoxylate Aminotransferase.
Biochem.J., 462, 2014

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