PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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3RL6	Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine and Adenosine monophosphate 分子名称: ADENOSINE MONOPHOSPHATE, ASPARAGINE, Archaeal asparagine synthetase A, ... 著者 Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D. 登録日 2011-04-19 公開日 2011-08-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases. J.Mol.Biol., 412, 2011
3CU8	Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome 分子名称: 14-3-3 protein zeta/delta, MAGNESIUM ION, PROPANOIC ACID, ... 著者 Schumacher, B, Weyand, M, Kuhlmann, J, Ottmann, C. 登録日 2008-04-16 公開日 2009-05-05 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling. Mol. Cell. Biol., 30, 2010
3REU	Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid and Adenosine triphosphate 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein, ... 著者 Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D. 登録日 2011-04-05 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases. J.Mol.Biol., 412, 2011
3WN7	Crystal Structure of Keap1 in Complex with the N-terminal region of the Nrf2 transcription factor 分子名称: ACETATE ION, Kelch-like ECH-associated protein 1, Peptide from Nuclear factor erythroid 2-related factor 2 著者 Fukutomi, T, Takagi, K, Mizushima, T, Ohuchi, N, Yamamoto, M. 登録日 2013-12-05 公開日 2013-12-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1 Mol.Cell.Biol., 34, 2014
7WTU	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1) 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7L7S	Human mitochondrial chaperonin mHsp60 分子名称: 60 kDa heat shock protein, mitochondrial 著者 Chen, L, Wang, J.C.Y. 登録日 2020-12-30 公開日 2021-08-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60. Sci Rep, 11, 2021
6J6H	Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom 分子名称: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
1A82	DETHIOBIOTIN SYNTHETASE FROM ESCHERICHIA COLI, COMPLEX WITH SUBSTRATES ATP AND DIAMINOPELARGONIC ACID 分子名称: 7,8-DIAMINO-NONANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, DETHIOBIOTIN SYNTHETASE, ... 著者 Kaeck, H, Gibson, K.J, Lindqvist, Y, Schneider, G. 登録日 1998-03-31 公開日 1999-05-11 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Snapshot of a phosphorylated substrate intermediate by kinetic crystallography. Proc.Natl.Acad.Sci.USA, 95, 1998
4N7Y	Crystal structure of 14-3-3zeta in complex with a 8-carbon-linker cyclic peptide derived from ExoS 分子名称: 14-3-3 protein zeta/delta, Exoenzyme S 著者 Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C. 登録日 2013-10-16 公開日 2014-02-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53, 2014
7MFE	Autoinhibited BRAF:(14-3-3)2 complex with the BRAF RBD resolved 分子名称: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf, ZINC ION 著者 Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K. 登録日 2021-04-09 公開日 2022-01-26 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding. Nat Commun, 13, 2022
7MFF	Dimeric (BRAF)2:(14-3-3)2 complex bound to SB590885 Inhibitor 分子名称: (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf 著者 Martinez Fiesco, J.A, Ping, Z, Durrant, D.E, Morrison, D.K. 登録日 2021-04-09 公開日 2022-01-26 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (3.89 Å) 主引用文献 Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding. Nat Commun, 13, 2022
4PTC	Structure of a carboxamide compound (3) (2-{2-[(CYCLOPROPYLCARBONYL)AMINO]PYRIDIN-4-YL}-4-OXO-4H-1LAMBDA~4~,3-THIAZOLE-5-CARBOXAMIDE) to GSK3b 分子名称: 2-[2-(cyclopropylcarbonylamino)pyridin-4-yl]-4-methoxy-1,3-thiazole-5-carboxamide, Glycogen synthase kinase-3 beta 著者 Lewis, H.A, Sivaprakasam, P, Kish, K, Pokross, M, Dubowchik, G.M. 登録日 2014-03-10 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.711 Å) 主引用文献 Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg.Med.Chem.Lett., 25, 2015
4NM3	Crystal structure of GSK-3/Axin complex bound to phosphorylated N-terminal auto-inhibitory pS9 peptide 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADENOSINE-5'-DIPHOSPHATE, Axin-1, ... 著者 Chu, M.L.-H, Stamos, J.L, Enos, M.D, Shah, N, Weis, W.I. 登録日 2013-11-14 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. Elife, 3, 2014
4NM0	Crystal structure of peptide inhibitor-free GSK-3/Axin complex 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADENOSINE-5'-DIPHOSPHATE, Axin-1, ... 著者 Chu, M.L.-H, Stamos, J.L, Enos, M.D, Shah, N, Weis, W.I. 登録日 2013-11-14 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. Elife, 3, 2014
6J6N	Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6J6Q	Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
7WU0	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B3 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7WTV	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A2 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7WTW	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7WTT	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1) 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7WTZ	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B2 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
7WTX	Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1 分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2022-02-05 公開日 2022-10-19 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
4PTE	Structure of a carvoxamide compound (15) (N-[4-(ISOQUINOLIN-7-YL)PYRIDIN-2-YL]CYCLOPROPANECARBOXAMIDE) to GSK3b 分子名称: Glycogen synthase kinase-3 beta, N-[4-(isoquinolin-7-yl)pyridin-2-yl]cyclopropanecarboxamide 著者 Lewis, H.A, Sivaprakasam, P, Kish, K, Pokross, M, Dubowchik, G.M. 登録日 2014-03-10 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.033 Å) 主引用文献 Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg.Med.Chem.Lett., 25, 2015
4PTG	Structure of a carboxamine compound (26) (2-{2-[(CYCLOPROPYLCARBONYL)AMINO]PYRIDIN-4-YL}-4-METHOXYPYRIMIDINE-5-CARBOXAMIDE) to GSK3b 分子名称: 2-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}-4-methoxypyrimidine-5-carboxamide, Glycogen synthase kinase-3 beta 著者 Lewis, H.A, Sivaprakasam, P, Kish, K, Pokross, M, Dubowchik, G.M. 登録日 2014-03-10 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.361 Å) 主引用文献 Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg.Med.Chem.Lett., 25, 2015
4N7G	Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS 分子名称: 14-3-3 protein zeta/delta, Exoenzyme S, HEXAETHYLENE GLYCOL 著者 Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C. 登録日 2013-10-15 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53, 2014

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