PDB: 238582 件ウェブページステータス検索Chemie searchBIRD

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3SMP	Monoclinic crystal structure of human pantothenate kinase 1 alpha 分子名称: ACETYL COENZYME *A, ARSENIC, CHLORIDE ION, ... 著者 Guan, X, Tempel, W, Hong, B, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2011-06-28 公開日 2011-07-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Monoclinic crystal structure of human pantothenate kinase 1 alpha to be published
3SNH	Crystal structure of nucleotide-free human dynamin1 分子名称: Dynamin-1 著者 Faelber, K, Daumke, O. 登録日 2011-06-29 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Crystal structure of nucleotide-free dynamin. Nature, 477, 2011
3S3B	Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization 分子名称: COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... 著者 Luna, V.M, Fee, J.A, Deniz, A.A, Stout, C.D. 登録日 2011-05-18 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Mobility of Xe atoms within the oxygen diffusion channel of cytochrome ba(3) oxidase. Biochemistry, 51, 2012
3S4K	Structure of a putative esterase Rv1847/MT1895 from Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Putative esterase Rv1847/MT1895, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-05-19 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of a putative esterase Rv1847/MT1895 from Mycobacterium tuberculosis To be Published
3S4S	Crystal structure of CD4 mutant bound to HLA-DR1 分子名称: GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Li, Y. 登録日 2011-05-20 公開日 2011-09-21 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
3S73	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase 分子名称: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Heroux, A, Whitesides, G.W. 登録日 2011-05-26 公開日 2011-12-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S6B	Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150 分子名称: FE (III) ION, GLYCEROL, Methionine aminopeptidase 著者 Wernimont, A.K, Artz, J.D, Crombet, L, Lew, J, Weadge, J, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Hui, R, Hills, T, Structural Genomics Consortium (SGC) 登録日 2011-05-25 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150 To be Published
3S86	Crystal Structure of TM0159 with bound IMP 分子名称: INOSINIC ACID, Nucleoside-triphosphatase, SULFATE ION 著者 Sommerhalter, M, Smith, C, Awwad, K, Desai, A. 登録日 2011-05-27 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and functional characterization of a noncanonical nucleoside triphosphate pyrophosphatase from Thermotoga maritima. Acta Crystallogr.,Sect.D, 69, 2013
3S71	The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase 分子名称: 1-benzofuran-2-sulfonamide, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Heroux, A, Whitesides, G.W. 登録日 2011-05-26 公開日 2011-10-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase. Proc.Natl.Acad.Sci.USA, 108, 2011
3S8X	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-05-31 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SA7	Crystal structure of wild-type HIV-1 protease in complex with AF55 分子名称: N~2~-acetyl-N-[(2S,3R)-4-{(1,3-benzothiazol-6-ylsulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-L-leucinamide, PHOSPHATE ION, Protease 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SAF	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site 分子名称: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION 著者 Januszyk, K, Liu, Q, Lima, C.D. 登録日 2011-06-02 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3SA8	Crystal structure of wild-type HIV-1 protease in complex with KB83 分子名称: 3-hydroxy-N-[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]benzamide, ACETATE ION, PHOSPHATE ION, ... 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SAG	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site 分子名称: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION 著者 Januszyk, K, Liu, Q, Lima, C.D. 登録日 2011-06-02 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3SBX	Crystal structure of a putative uncharacterized protein from Mycobacterium marinum bound to adenosine 5'-monophosphate AMP 分子名称: ADENOSINE MONOPHOSPHATE, Putative uncharacterized protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-06-06 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3SB8	Cu-mediated Dimer of T4 Lysozyme D61H/K65H by Synthetic Symmetrization 分子名称: COPPER (II) ION, Lysozyme 著者 Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. 登録日 2011-06-03 公開日 2011-09-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
3SC0	Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin 分子名称: CO-METHYLCOBALAMIN, Methylmalonic aciduria and homocystinuria type C protein 著者 Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. 登録日 2011-06-06 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis of multifunctionality in a vitamin B12-processing enzyme. J.Biol.Chem., 286, 2011
3SD0	Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice 分子名称: 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glycogen synthase kinase-3 beta 著者 Mesecar, A.M, Walters, R.L. 登録日 2011-06-08 公開日 2011-08-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice To be Published
3SDK	Structure of yeast 20S open-gate proteasome with Compound 34 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-[(2S)-3-(3-tert-butyl-1,2,4-oxadiazol-5-yl)-1-({(2S)-1-[(4-methylbenzyl)amino]-1-oxo-4-phenylbutan-2-yl}amino)-1-oxopropan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide, ... 著者 Sintchak, M.D. 登録日 2011-06-09 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010
3SD3	The structure of the tetrahydrofolate riboswitch containing a U25C mutation 分子名称: IRIDIUM HEXAMMINE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, Tetrahydrofolate riboswitch 著者 Reyes, F.E, Trausch, J.J, Ceres, P, Batey, R.T. 登録日 2011-06-08 公開日 2011-09-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer. Structure, 19, 2011
3SH2	Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J) 分子名称: 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Frey, K.M, Anderson, A.C. 登録日 2011-06-15 公開日 2012-03-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes. Plos One, 7, 2012
3SHY	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors 分子名称: 6-ethyl-5-fluoro-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... 著者 Chen, T.T, Chen, T, Xu, Y.C. 登録日 2011-06-17 公開日 2011-08-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.647 Å) 主引用文献 Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J.Med.Chem., 54, 2011
3SF0	Structure of Recombinant Haemophilus Influenzae e(P4) Acid Phosphatase mutant D64N complexed with 5'AMP 分子名称: ADENOSINE MONOPHOSPHATE, Lipoprotein E, MAGNESIUM ION 著者 Singh, H. 登録日 2011-06-12 公開日 2011-09-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural basis of the inhibition of class C acid phosphatases by adenosine 5'-phosphorothioate. Febs J., 278, 2011
3SIX	Crystal structure of NodZ alpha-1,6-fucosyltransferase soaked with GDP-fucose 分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Nodulation fucosyltransferase NodZ, ... 著者 Brzezinski, K, Dauter, Z, Jaskolski, M. 登録日 2011-06-20 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structures of NodZ alpha-1,6-fucosyltransferase in complex with GDP and GDP-fucose Acta Crystallogr.,Sect.D, 68, 2012
3SGN	Bromoderivative-8 of amyloid-related segment of alphaB-crystallin residues 90-100 分子名称: Alpha-crystallin B chain 著者 Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2011-06-15 公開日 2012-03-21 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 Atomic view of a toxic amyloid small oligomer. Science, 335, 2012

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