3SA8

Crystal structure of wild-type HIV-1 protease in complex with KB83

Summary for 3SA8

• Entry DOI: 10.2210/pdb3sa8/pdb
• Related: 3SA3 3SA4 3SA5 3SA6 3SA7 3SA9 3SAA 3SAB 3SAC
• Related PRD ID: PRD_000951
• Descriptor: Protease, PHOSPHATE ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: hiv-1 protease, drug resistance, drug design, protease inhibitors, aids, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 2
• Total formula weight: 22656.20

Authors

Schiffer, C.A.,Nalam, M.N.L. (deposition date: 2011-06-02, release date: 2012-06-06, Last modification date: 2023-09-13)

• Primary citation: Altman, M.D.,Nalam, M.N.L.,Ali, A.,Cao, H.,Rana, T.M.,Schiffer, C.A.,Tidor, B.; Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)