1KXP
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1KW2
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1J78
| Crystallographic analysis of the human vitamin D binding protein | 分子名称: | 3-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANOL, OLEIC ACID, vitamin D binding protein | 著者 | Verboven, C, Rabijns, A, De Maeyer, M, Van Baelen, H, Bouillon, R, De Ranter, C. | 登録日 | 2001-05-16 | 公開日 | 2002-02-06 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | A structural basis for the unique binding features of the human vitamin D-binding protein. Nat.Struct.Biol., 9, 2002
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5WTD
| Structure of human serum transferrin bound ruthenium at N-lobe | 分子名称: | FE (III) ION, MALONATE ION, RUTHENIUM ION, ... | 著者 | Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q. | 登録日 | 2016-12-11 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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6RQ7
| Gadolinium MRI contrast compound binding in human plasma glycoprotein afamin - resurrection of highly anisotropic data | 分子名称: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rupp, B, Bowler, M.W, Naschberger, A, Juyoux, P, vonVelsen, J. | 登録日 | 2019-05-15 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Controlled dehydration, structural flexibility and gadolinium MRI contrast compound binding in the human plasma glycoprotein afamin. Acta Crystallogr D Struct Biol, 75, 2019
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7FFM
| Human serum transferrin with five osmium binding sites | 分子名称: | MALONATE ION, NITRILOTRIACETIC ACID, OSMIUM ION, ... | 著者 | Wang, M, Sun, H. | 登録日 | 2021-07-23 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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7FFU
| Osmium-bound human serum transferrin | 分子名称: | FE (III) ION, MALONATE ION, OSMIUM ION, ... | 著者 | Wang, M, Sun, H. | 登録日 | 2021-07-23 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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2QTJ
| Solution structure of human dimeric immunoglobulin A | 分子名称: | Ig alpha-1 chain C region, Kappa light chain IgA1 | 著者 | Bonner, A, Furtado, P.B, Almogren, A, Kerr, M.A, Perkins, S.J. | 登録日 | 2007-08-02 | 公開日 | 2008-01-22 | 最終更新日 | 2024-02-21 | 実験手法 | SOLUTION SCATTERING | 主引用文献 | Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy J.Immunol., 180, 2008
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8COE
| complement C5 in complex with the LCP0195 nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, Complement C5 beta chain, ... | 著者 | Andersen, G.R, Pedersen, D.V. | 登録日 | 2023-02-28 | 公開日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration. Mol.Immunol., 165, 2023
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8COH
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6ZIE
| Crystal structure of MCL-1 in complex with a neutralizing Alphabody CMPX-383B | 分子名称: | CMPX-383B, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION | 著者 | Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I. | 登録日 | 2020-06-25 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting. Sci Adv, 7, 2021
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8AXX
| Expanded Coxsackievirus A9 after treatment with endosomal ionic buffer | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | 著者 | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | 登録日 | 2022-09-01 | 公開日 | 2022-10-19 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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8AW6
| Expanded Coxsackievirus A9 after 0.01% faf-BSA treatment | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | 著者 | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | 登録日 | 2022-08-29 | 公開日 | 2022-10-26 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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8AT5
| native Coxsackievirus A9 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | 著者 | Domanska, A, Plavec, Z, Ruokolainen, V, Marjomaki, V.S, Butcher, S.J. | 登録日 | 2022-08-22 | 公開日 | 2022-11-16 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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4ZGM
| Crystal structure of Semaglutide peptide backbone in complex with the GLP-1 receptor extracellular domain | 分子名称: | 3,6,9,12,15,18-hexaoxahexacosan-1-ol, Glucagon-like peptide 1 receptor, Semaglutide peptide backbone; 8Aib,34R-GLP-1(7-37)-OH | 著者 | Reedtz-Runge, S. | 登録日 | 2015-04-23 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide. J.Med.Chem., 58, 2015
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7WQL
| Bovin Beta-lactoglobulin binding with zinc ions | 分子名称: | Beta-lactoglobulin, ZINC ION | 著者 | Li, T, Ma, J, Zang, J, Zhao, G, Zhang, T. | 登録日 | 2022-01-25 | 公開日 | 2022-08-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Zinc binding strength of proteins dominants zinc uptake in Caco-2 cells. Rsc Adv, 12, 2022
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7WQG
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2ROY
| TRANSTHYRETIN (ALSO CALLED PREALBUMIN) COMPLEX WITH 3',5'-DINITRO-N-ACETYL-L-THYRONINE | 分子名称: | 3',5'-DINITRO-N-ACETYL-L-THYRONINE, TRANSTHYRETIN | 著者 | Wojtczak, A, Cody, V, Luft, J.R, Pangborn, W. | 登録日 | 1996-10-23 | 公開日 | 1997-04-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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1Z7J
| Human transthyretin (also called prealbumin) complex with 3, 3',5,5'-tetraiodothyroacetic acid (t4ac) | 分子名称: | 3,3',5,5'-TETRAIODOTHYROACETIC ACID, Transthyretin | 著者 | Neumann, P, Wojtczak, A, Cody, V. | 登録日 | 2005-03-25 | 公開日 | 2005-06-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution. Acta Crystallogr.,Sect.D, 61, 2005
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2ROX
| TRANSTHYRETIN (ALSO CALLED PREALBUMIN) COMPLEX WITH THYROXINE (T4) | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, SULFATE ION, TRANSTHYRETIN | 著者 | Wojtczak, A, Cody, V, Luft, J.R, Pangborn, W. | 登録日 | 1996-10-23 | 公開日 | 1997-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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5FUC
| Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-6, INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, ... | 著者 | Adams, R, Griffin, R, Doyle, C, Ettorre, A. | 登録日 | 2016-01-25 | 公開日 | 2017-01-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling. Sci Rep, 7, 2017
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1ICT
| MONOCLINIC FORM OF HUMAN TRANSTHYRETIN COMPLEXED WITH THYROXINE (T4) | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN | 著者 | Wojtczak, A, Neumann, P, Cody, V. | 登録日 | 2001-04-02 | 公開日 | 2002-04-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of a new polymorphic monoclinic form of human transthyretin at 3 A resolution reveals a mixed complex between unliganded and T4-bound tetramers of TTR. Acta Crystallogr.,Sect.D, 57, 2001
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5WHJ
| Crystal structure of Fab fragment of anti-FcRn antibody DX-2507 | 分子名称: | DX-2507 Fab heavy chain, DX-2507 Fab light chain | 著者 | Edwards, T.E, Fairman, J.W, Nixon, A.E, Kenniston, J.A. | 登録日 | 2017-07-17 | 公開日 | 2017-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody. J. Biol. Chem., 292, 2017
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5WHK
| Crystal structure of Fab fragment of antibody DX-2507 bound to FcRn-B2M | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, ... | 著者 | Edwards, T.E, Clifton, M.C, Nixon, A.E, Kenniston, J.A. | 登録日 | 2017-07-17 | 公開日 | 2017-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody. J. Biol. Chem., 292, 2017
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1MLX
| Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*SMTP*AP*CP*GP*C)-3' | 著者 | Prakash, T.P, Manoharan, M, Kawasaki, A.M, Fraser, A.S, Lesnik, E.A, Sioufi, N, Leeds, J.M, Teplova, M, Egli, M. | 登録日 | 2002-08-31 | 公開日 | 2002-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | 2'-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2'-O-[2-(Methoxy)-ethyl]-Modified
Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA Biochemistry, 41, 2002
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