1J7E

A Structural Basis for the Unique Binding Features of the Human Vitamin D-binding Protein

Summary for 1J7E

Related1J78
Descriptorvitamin D binding protein, 3-(2-{4-[2-(5-HYDROXY-2-METHYLENE-CYCLOHEXYLIDENE)-ETHYLIDENE]-7A-METHYL-OCTAHYDRO-INDEN-1-YL}-PROPYL)-PHENOL, OLEIC ACID, ... (4 entities in total)
Functional Keywordsvitamin d binding, vitamin d3 analogue, group-specific component, gc-globulin, transport, ligand binding protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted  P02774
Total number of polymer chains2
Total molecular weight104215.16
Authors
Verboven, C.,Rabijns, A.,De Maeyer, M.,Van Baelen, H.,Bouillon, R.,De Ranter, C. (deposition date: 2001-05-16, release date: 2002-02-06, Last modification date: 2018-01-31)
Primary citation
Verboven, C.,Rabijns, A.,De Maeyer, M.,Van Baelen, H.,Bouillon, R.,De Ranter, C.
A structural basis for the unique binding features of the human vitamin D-binding protein.
Nat.Struct.Biol., 9:131-136, 2002
PubMed: 11799400 (PDB entries with the same primary citation)
DOI: 10.1038/nsb754
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.55 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.264171.3%1.9%5.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload