1J7E
A Structural Basis for the Unique Binding Features of the Human Vitamin D-binding Protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0005499 | molecular_function | vitamin D binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0031667 | biological_process | response to nutrient levels |
| A | 0035461 | biological_process | vitamin transmembrane transport |
| A | 0042359 | biological_process | vitamin D metabolic process |
| A | 0043202 | cellular_component | lysosomal lumen |
| A | 0051180 | biological_process | vitamin transport |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0072562 | cellular_component | blood microparticle |
| A | 0090482 | molecular_function | vitamin transmembrane transporter activity |
| A | 0140104 | molecular_function | molecular carrier activity |
| A | 1902118 | molecular_function | calcidiol binding |
| B | 0003779 | molecular_function | actin binding |
| B | 0005499 | molecular_function | vitamin D binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0031667 | biological_process | response to nutrient levels |
| B | 0035461 | biological_process | vitamin transmembrane transport |
| B | 0042359 | biological_process | vitamin D metabolic process |
| B | 0043202 | cellular_component | lysosomal lumen |
| B | 0051180 | biological_process | vitamin transport |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0072562 | cellular_component | blood microparticle |
| B | 0090482 | molecular_function | vitamin transmembrane transporter activity |
| B | 0140104 | molecular_function | molecular carrier activity |
| B | 1902118 | molecular_function | calcidiol binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE JY A 501 |
| Chain | Residue |
| A | GLU8 |
| A | SER79 |
| A | MET107 |
| A | HOH521 |
| B | ASP364 |
| B | THR367 |
| A | VAL12 |
| A | GLU15 |
| A | SER28 |
| A | LEU31 |
| A | TYR32 |
| A | LYS35 |
| A | LEU75 |
| A | SER76 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE JY B 502 |
| Chain | Residue |
| B | GLU8 |
| B | GLU15 |
| B | LEU27 |
| B | SER28 |
| B | TYR32 |
| B | PHE36 |
| B | LEU47 |
| B | TYR68 |
| B | SER76 |
| B | SER79 |
| B | MET107 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OLA A 502 |
| Chain | Residue |
| A | VAL348 |
| A | GLU350 |
| A | PRO351 |
| A | LYS354 |
| A | GLU379 |
| A | PHE383 |
| A | ASP451 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE OLA B 503 |
| Chain | Residue |
| B | GLU379 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE OLA B 504 |
| Chain | Residue |
| A | ASP361 |
| B | ALA208 |
| B | ALA209 |
| B | TYR210 |
| B | LYS214 |
| B | LEU444 |
Functional Information from PROSITE/UniProt
| site_id | PS00212 |
| Number of Residues | 25 |
| Details | ALBUMIN_1 Albumin domain signature. YlsmvgsCCtsAsptvCFlkerlqL |
| Chain | Residue | Details |
| A | TYR166-LEU190 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 370 |
| Details | Domain: {"description":"Albumin 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
