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4QNQ
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BU of 4qnq by Molmil
Crystal Structure Analysis of full-length Bcl-XL in complex with the inhibitor ABT-263
分子名称: 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide, Bcl-2-like protein 1
著者Korste, A, Vetter, I.R, Stoll, R.
登録日2014-06-18
公開日2015-10-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure Analysis of full-length Bcl-XL in complex with the inhibitor ABT-263
TO BE PUBLISHED
5WTD
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BU of 5wtd by Molmil
Structure of human serum transferrin bound ruthenium at N-lobe
分子名称: FE (III) ION, MALONATE ION, RUTHENIUM ION, ...
著者Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q.
登録日2016-12-11
公開日2017-12-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
4BX8
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BU of 4bx8 by Molmil
Human Vps33A
分子名称: CHLORIDE ION, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A
著者Graham, S.C, Wartosch, L, Gray, S.R, Scourfield, E.J, Deane, J.E, Luzio, J.P, Owen, D.J.
登録日2013-07-09
公開日2013-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Vps33A Recruitment to the Human Hops Complex by Vps16.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BX9
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BU of 4bx9 by Molmil
Human Vps33A in complex with a fragment of human Vps16
分子名称: (2S)-2-hydroxybutanedioic acid, FORMIC ACID, MALONIC ACID, ...
著者Graham, S.C, Wartosch, L, Gray, S.R, Scourfield, E.J, Deane, J.E, Luzio, J.P, Owen, D.J.
登録日2013-07-09
公開日2013-07-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
2BZW
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BU of 2bzw by Molmil
The crystal structure of BCL-XL in complex with full-length BAD
分子名称: APOPTOSIS REGULATOR BCL-X, BCL2-ANTAGONIST OF CELL DEATH
著者Lee, K.-H, Han, W.-D, Kim, K.-J, Oh, B.-H.
登録日2005-08-24
公開日2007-02-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral Bcl-2 of Murine Gamma-Herpesvirus 68.
Plos Pathog., 4, 2008
6XSW
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BU of 6xsw by Molmil
Structure of the Notch3 NRR in complex with an antibody Fab Fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-N3 Fab Heavy Chain, ...
著者Bard, J.
登録日2020-07-16
公開日2021-07-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells.
Cell Rep Med, 2, 2021
6SOY
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BU of 6soy by Molmil
Trypanosoma brucei transferrin receptor in complex with human transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, subunit of heterodimeric transferrin receptor, ...
著者Trevor, C, Carrington, M, Higgins, M.K.
登録日2019-08-30
公開日2019-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
4X1D
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BU of 4x1d by Molmil
Ytterbium-bound human serum transferrin
分子名称: GLYCEROL, MALONATE ION, Serotransferrin, ...
著者Wang, M, Zhang, H, Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
6SOZ
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BU of 6soz by Molmil
Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ...
著者Trevor, C, Carrington, M, Higgins, M.K.
登録日2019-08-30
公開日2019-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
4H0W
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BU of 4h0w by Molmil
Bismuth bound human serum transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bismuth(III) ION, CARBONATE ION, ...
著者Yang, N, Zhang, H, Wang, M, Hao, Q, Sun, H.
登録日2012-09-10
公開日2012-12-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe.
Sci Rep, 2, 2012
4ATM
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BU of 4atm by Molmil
Crystal structure of the BAR domain of human Amphiphysin, isoform 1 at 1.8 Angstrom resolution featuring increased order at the N- terminus.
分子名称: 1,2-ETHANEDIOL, AMPHIPHYSIN, GLYCEROL
著者Allerston, C.K, Krojer, T, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O.
登録日2012-05-08
公開日2012-05-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.783 Å)
主引用文献Crystal Structure of the Bar Domain of Human Amphiphysin, Isoform 1
To be Published
4X1B
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BU of 4x1b by Molmil
Human serum transferrin with ferric ion bound at the C-lobe only
分子名称: FE (III) ION, GLYCEROL, MALONATE ION, ...
著者Wang, M, Zhang, H, Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
7AX3
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BU of 7ax3 by Molmil
CryoEM structure of the super-constricted two-start dynamin 1 filament
分子名称: Dynamin-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Liu, J.W, Zhang, P.J.
登録日2020-11-09
公開日2021-11-10
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献CryoEM structure of the super-constricted two-start dynamin 1 filament.
Nat Commun, 12, 2021
2EFL
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BU of 2efl by Molmil
Crystal structure of the EFC domain of formin-binding protein 17
分子名称: Formin-binding protein 1
著者Shimada, A, Niwa, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-23
公開日2007-05-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
Cell(Cambridge,Mass.), 129, 2007
2EFK
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BU of 2efk by Molmil
Crystal structure of the EFC domain of Cdc42-interacting protein 4
分子名称: Cdc42-interacting protein 4
著者Shimada, A, Niwa, H, Chen, L, Liu, Z.-J, Wang, B.-C, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-23
公開日2007-05-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
Cell(Cambridge,Mass.), 129, 2007
6JAS
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BU of 6jas by Molmil
Human serum transferrin with iron citrate bound
分子名称: CITRIC ACID, FE (III) ION, MALONATE ION, ...
著者Wang, M, Wang, H, Sun, H.
登録日2019-01-25
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Binding of ruthenium and osmium at non-iron sites of transferrin explains their iron-independent cellular uptake
To Be Published
7ZQS
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BU of 7zqs by Molmil
Cryo-EM Structure of Human Transferrin Receptor 1 bound to DNA Aptamer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (30-MER), ...
著者Bansia, H, Wang, T, Gutierrez, D, des Georges, A.
登録日2022-05-02
公開日2022-08-17
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T-Cell Therapy Manufacturing.
J.Am.Chem.Soc., 144, 2022
3QYT
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BU of 3qyt by Molmil
Diferric bound human serum transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Yang, N, Zhang, H, Wang, M, Hao, Q, Sun, H.
登録日2011-03-03
公開日2012-03-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
Sci Rep, 2, 2012
3S9N
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BU of 3s9n by Molmil
Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ...
著者Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J.
登録日2011-06-01
公開日2011-08-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
8BRC
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BU of 8brc by Molmil
Crystal structure of the adduct between human serum transferrin and cisplatin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIA, FE (III) ION, ...
著者Troisi, R, Galardo, F, Ferraro, G, Sica, F, Merlino, A.
登録日2022-11-22
公開日2023-01-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study.
Inorg.Chem., 62, 2023
3S9M
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BU of 3s9m by Molmil
Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ...
著者Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J.
登録日2011-06-01
公開日2011-08-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
3S9L
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BU of 3s9l by Molmil
Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ...
著者Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J.
登録日2011-06-01
公開日2011-08-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
3MV3
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Crystal Structure of a-COP in Complex with e-COP
分子名称: Coatomer subunit alpha, Coatomer subunit epsilon
著者Hoelz, A, Hsia, K.C.
登録日2010-05-03
公開日2010-06-16
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal structure of alpha-COP in complex with epsilon-COP provides insight into the architecture of the COPI vesicular coat.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MV2
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BU of 3mv2 by Molmil
Crystal Structure of a-COP in Complex with e-COP
分子名称: Coatomer subunit alpha, Coatomer subunit epsilon
著者Hoelz, A, Hsia, K.C.
登録日2010-05-03
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of alpha-COP in complex with epsilon-COP provides insight into the architecture of the COPI vesicular coat.
Proc.Natl.Acad.Sci.USA, 107, 2010
3VE1
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The 2.9 angstrom crystal structure of Transferrin binding protein B (TbpB) from serogroup B M982 Neisseria meningitidis in complex with human transferrin
分子名称: CARBONATE ION, FE (III) ION, GLYCEROL, ...
著者Calmettes, C, Moraes, T.F.
登録日2012-01-06
公開日2012-02-22
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (2.956 Å)
主引用文献The structural basis of transferrin sequestration by transferrin-binding protein B.
Nat.Struct.Mol.Biol., 19, 2012

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